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Sir Jonathan Hutchinson was born at Selby, Yorkshire, on 23 July 1828, the son of Jonathan Hutchinson, a middleman in the flax trade and a member of the Society of Friends. Brought up as a Quaker, Hutchinson remained influenced by the doctrine of the Quakers throughout his life. He was educated at Selby and then apprenticed to the surgeon Caleb Williams of York in 1845. Between 1846 and 1850 Hutchinson attended both the York School of Medicine, where Williams lectured on materia medica and therapeutics, and the York County Hospital. Hutchinson went to London in 1849 to complete his medical training at St Bartholomew's Hospital. In 1850 he became a member of the Royal College of Surgeons, and a licentiate of the Society of Apothecaries.

Disliking the thought of private practice, he began his medical career writing for the medical journals, and coaching pupils for examinations. From 1853 he wrote weekly hospital reports for the Medical Times and Gazette. He remained a prolific writer throughout his career. In the early 1850s he was also appointed as clinical assistant to the Liverpool Street Chest Hospital, assistant surgeon to the Metropolitan Free Hospital, and soon afterwards joined the staff of the Royal London Ophthalmic Hospital and the Blackfriars Hospital for Skin Diseases. After marrying Jane Pynsent West in 1856, he began private practice in London. In 1859 he was appointed assistant surgeon to the London Hospital.

Hutchinson helped found the New Sydenham Society in 1859, after the dissolution of the original Sydenham Society. He was its secretary throughout its existence, until 1907, and was responsible for editing the many publications of the Society. He was appointed assistant surgeon to the Royal Lock Hospital, and full surgeon to the Royal London Ophthalmic Hospital, in 1862, and in the same year became lecturer on surgery at the London Hospital. Also in 1862 Hutchinson became a fellow of the Royal College of Surgeons. In 1863 he became full surgeon at the London Hospital and began to lecture in medical ophthalmology, as well as surgery. Due to his new posts he stopped writing his weekly reports for the Medical Times and Gazette. 1863 also saw the publication of his book on inherited syphilis, A Clinical Memoir on Certain Diseases of the Eye and Ear, Consequent on Inherited Syphilis.

Hutchinson became a leading authority on the subjects of ophthalmology, dermatology, neurology, and in particular syphilis, and has been described as `the greatest general practitioner in Europe' (DNB, 1927, p.279). He promulgated the view that syphilis is a specific fever like smallpox or measles. His skill lay in observation, and the accumulation and collation of clinical facts. However his deductions from them were not always convincing, such as his conclusion that leprosy was caused by the consumption of decaying fish. Even after the discovery of the lepra bacillus Hutchinson did not change his opinion, despite being in direct opposition to the rest of the medical profession.

In 1868 he helped to establish the pathological museum held in connection with the annual meetings of the British Medical Association (BMA). From 1869-70 Hutchinson edited the British Medical Journal. In 1874 he moved to larger premises at 15 Cavendish Square, next door to his famous medical colleague Sir Andrew Clark. He was President of the Section of Surgery of the BMA in 1876. In 1878 the first volume of his Illustrations of Clinical Surgery (1878-84) appeared, consisting of drawings, photographs, and diagrams illustrating diseases, symptoms, and injuries with full explanations. From 1879-95 he served on the council of the Royal College of Surgeons, and between 1879-83 was their Hunterian Professor of Surgery and Pathology. He served on the Royal Commission on Smallpox and Fever Cases in London Hospitals, in 1881. In 1882 he was elected fellow of the Royal Society.

In 1883 he left the active service of the London Hospital, and became emeritus professor of surgery at the Hospital's medical school. The Hutchinson triennial prize essay was established to commemorate his services to the Hospital. Hutchinson became president of the Royal College of Surgeons in 1889, and began the publication of his series Archives of Surgery (1889-1900), which was issued quarterly, and proved of interest to general practitioners, surgeons, physicians, and specialists. From 1890-96 he served on the Royal Commission on Vaccination. In 1891 he delivered the Hunterian Oration of the Royal College of Surgeons. In 1895 he published A Smaller Atlas of Illustrations of Clinical Surgery.

Over the years Hutchinson acquired a vast collection of specimens and watercolour drawings. He donated his collections and a large number of books and periodicals to the Medical Graduates' College and Polyclinic at 22 Chenies Street, founded in 1899. Hutchinson played a major part instigating the foundation of the College, and, along with others, gave courses of lectures and demonstrations, as well as free consultations for impoverished patients. These public consultations were popular and largely attended by general practitioners. He also assumed the editorship of the College's journal, The Polyclinic.

Hutchinson established an educational museum and library at his own expense at his country house in Haslemere, Surrey, which included an aviary and vivarium, where he spent much of his time with his childhood friend the eminent neurologist John Hughlings Jackson. Hutchinson gave lectures and demonstrations to the local community on scientific, literary and religious subjects at the weekends. Edward VII knew of him as `the surgeon who had a hospital for animals on his farm' (Plarr, 1930, p.590). Hutchinson established a similar museum in his native Selby, but this proved less popular.

In 1907 he moved to Gower Street, to be closer to the Graduates' College in Chenies Street. He was knighted in 1908 for his distinguished services to medicine. It is said that he refused an earlier offering of a peerage and had to be persuaded by friends to accept this knighthood. He received honorary degrees from the universities of Glasgow, Cambridge, Edinburgh, Oxford, Dublin, and Leeds, and was a corresponding member of the Societe de Chirurgie de Paris. At various times he held the presidency of several London medical societies, including the Royal Medical and Chirurgical, Pathological, Hunterian, Ophthalmological, Medical, and Neurological Societies.

Hutchinson had a large family, with six sons, four of who survived him, and four daughters. His wife died in 1886. Hutchinson died at his house in Haslemere, Surrey, on 26 June 1913. He was buried in Haslemere, with a tombstone that was inscribed on his orders, `A Man of Hope and Forward-Looking Mind'.

Publications:
A Clinical Memoir on Certain Diseases of the Eye and Ear, Consequent on Inherited Syphilis (London, 1863)
A Descriptive Catalogue of the New Sydenham Society's Atlas of Portraits of Diseases of the Skin (London, 1869-75)
An Atlas of Illustrations of Pathology, Jonathan Hutchinson (ed.) (New Sydenham Society, London, 1877-1900)
Atlas of Skin Diseases, Jonathan Hutchinson (ed.) (New Sydenham Society, London, 1800s)
Illustrations of Clinical Surgery (2 Vols., London, 1878-88)
The Pedigree of Disease (1884)
Syphilis (London, 1887)
A Smaller Atlas of Illustrations of Clinical Surgery (1895)
Archives of Surgery (London, 1889-1900)
Atlas of Clinical Medicine, Surgery and Pathology, Jonathan Hutchinson (ed.) (New Sydenham Society, London, 1901-7)
Leprosy and Fish-Eating, A Statement of Facts and Explanations (1906)
A System of Syphilis; with an Introduction by Sir Jonathan Hutchinson, Sir D'Arcy Power, James Keogh Murphy & Sir Jonathan Hutchinson (London, 1908-10)
Retrospective Memoranda, by Sir Jonathan Hutchinson, and Subject Index and Index of Names compiled by Charles R. Hewitt (New Sydenham Society, London, 1911)
Neurological Fragments of J.H. Jackson; with Biographical Memoir by James Taylor, and including the Recollections of Sir Jonathan Hutchinson, and Charles Mercier, John Hughlings Jackson, James Taylor, Sir Jonathan Hutchinson, and Charles Arthur Mercier (London, 1925)

Publications by others about Hutchinson
The Life and Letters of Jonathan Hutchinson, Herbert Hutchinson (London, 1946)

Edward Jenner was born in Berkeley, Gloucestershire, on 17 May 1749, the youngest son of Stephen Jenner, vicar at Berkeley. His father died when Jenner was five years old, and his eldest brother Stephen directed his education. From the age of eight he was sent to school at nearby Wotton-under-Edge, and then to Cirencester Grammar School. During his time at Cirencester Jenner developed an interest in natural history, collecting the fossils that were abundant in the area. In 1761 he was apprenticed to a surgeon, Daniel Ludlow of Sodbury, before, at the age of 21, enrolling as a resident house pupil of the great surgeon John Hunter, in London. Over the next two years he received his most important education, and began a lifelong friendship with Hunter. On Hunter's recommendation Jenner was employed to prepare some of the specimens brought back from James Cook's circumnavigation of the world in 1771. He went on to pursue his studies at St George's Hospital, London.

In 1773 he returned to Berkeley to set up practice, and soon became successful. In his spare time he made botanical and ornithological observations, continued to collect fossils, played the flute and violin, and wrote poetry. He made observations on the temperature of animals. Hunter encouraged him in this task, and upon his request Jenner sent him specimens of salmon-spawn, porpoises, cuckoos, and fossils.

Jenner helped establish a medical society in Rodborough, Gloucestershire, whose members met to read papers on medical subjects before dining together. Jenner contributed papers on angina pectoris, ophthalmia and valvular disease of the heart and commented on cowpox, which had already begun to concern him. He also belonged to a similar society which met in Alveston, near Bristol. In 1787 Jenner wrote a paper on the `Natural History of the Cuckoo', which was published in the Philosophical Transactions the following year. Some discrepancies exist in the text; due it is thought to the fact that Jenner had instructed his nephew to make the observations. The latter, upon being directed by Jenner to perform this task, gave his uncle an imaginary report. In 1788 he was elected Fellow of the Royal Society. It was in March of that year that Jenner married Catharine Kingscote.

Jenner's burgeoning practice forced him to give up surgery and midwifery. In 1792 he obtained his MD from the University of St Andrews. In 1793 he published `A Process for Preparing Pure Emetic Tartar by Recrystallisation' in the Transactions of the Society for the Improvement of Medical and Chirurgical Knowledge.

In 1794 Jenner suffered severely from typhus fever. Upon his recovery he continued his investigations into the protective power of cowpox against smallpox, the commonest of diseases affecting all levels of society. He was at this time well aware of the widely held belief that diary maids who had contracted cowpox did not get smallpox. In May 1796 he vaccinated a young boy with lymph taken from vesicles of cowpox, which the boy accordingly developed. The boy was then inoculated with smallpox in July, which did not develop thus proving Jenner's argument. Jenner summarised his observations in a paper, `On the Cow-pox, the Original Paper', which was never printed. He stayed in London from April to July 1798 publicising his discovery in medical circles, however he failed to find any volunteers for vaccination. In June 1798 he published a fuller account, which became a medical classic, An Inquiry into the Cause and Effects of the Variolae Vaccinae, a Disease Discovered in Some of the Western Counties of England, Particularly Gloucestershire, and Known by the Name of the Cow-pox. Interest did arise after Jenner's return to Berkeley, from a surgeon at St Thomas's Hospital, London, who was vaccinating patients with lymph given to him by Jenner, but Jenner was not keen to return to the capital.

Opposition to Jenner's discovery inevitably arose and, in reply to his critics, Jenner published Further Observations on the Variolae Vaccinae or Cow-pox (1799). He continued his work on vaccination in Berkeley and in Cheltenham, before returning to London in March 1799. From 1800 he lived in the capital for part of each year. The practice of vaccination slowly began to gain ground, though errors due to carelessness and ignorance did occur. Developments included discussion on the establishment of a vaccine institution, sending lymph throughout England and abroad, being presented to the King and then the Queen, and vaccinating the 85th regiment and then the British fleet. In 1800 he published A Continuation of Facts and Observations Relative to the Variolae Vaccinae or Cow-pox, and A Complete Statement of Facts and Observations Relative to the Cow-pock. During 1801 he received a number of congratulatory addresses and medals, including a medal from the medical officers of the British fleet, a ring from the Empress of Russia, and a service of plate from the gentry of Gloucestershire.

In 1802, on the advice of his friends, he petitioned Parliament for remuneration due to the time spent on his discovery preventing him acquiring his professional income. With the King's recommendation the petition went to a committee, which investigated the usefulness of the discovery and Jenner's right to claim to be the discoverer. It was proposed that he be granted £10,000. It has been said that whilst he sought just public reward for his services he showed `complete freedom from any wish to enrich himself unworthily when riches were in his power' (DNB, 1892, p.324). Jenner returned to Berkeley until February 1803, when he again visited London. He became involved with the Jennerian Institution, a society concerned with promoting vaccination to eradicate smallpox. In 1808, with government aid, this society became the National Vaccine Establishment.

Jenner took a house in Mayfair and set up practice as a physician, but success was not forthcoming and he returned to Berkeley. He became a member of the Medical and Chirurgical Society on its foundation in 1805, and subsequently presented to them a number of papers. With his professional practice so impeded by his work promoting vaccination he again applied to Parliament for aid in 1806. An inquiry set up by the Royal College of Physicians reported favourably on the advantages of vaccination and the merits of Jenner. The House of Commons consequently awarded him £20,000.

In 1811 he was seriously ill. Upon his recovery he returned to London, and noticed that a significant number of cases of smallpox after vaccination were occurring. He found that in these cases the severity of the illness was notably diminished by the previous vaccination. In 1813 the University of Oxford awarded him the degree of MD.

In April 1814 he visited London for the last time, and stayed three months. He met the Czar, his sister the Duchess of Oldenburg, and the King of Prussia. He then returned first to Cheltenham, where his wife died in 1815, and then to live in Berkeley. In 1820 Jenner had an apoplexy attack from which he completely recovered. In 1821 he was appointed Physician Extraordinary to King George IV and was made Mayor of Berkeley and Justice of the Peace. In 1822 he published A Letter to C.H. Parry, MD, on the Influence of Artificial Eruptions in Certain Diseases Incidental to the Human Body, and wrote Observations on the Migration of Birds (1823), which he read to the Royal Society on 23 November 1822.

On 26 January 1823 he had another attack of apoplexy and died, one son and one daughter survived him, the eldest son having died of tuberculosis at the age of 21. Jenner was buried on 3 February 1823 in the chancel of the parish church of Berkeley. A marble statue of Jenner was erected in the nave of Gloucester Cathedral, whilst a bronze statue was erected in Trafalgar Square in 1858, which was moved to Kensington Gardens in 1862. Jenner made an invaluable contribution to medicine, with innumerable lives being saved throughout the world by his discovery. Vaccination became compulsory in the United Kingdom in 1853, and spread throughout Europe during the nineteenth century. In 1967 the World Health Organisation (WHO) launched a worldwide vaccination programme; by 1979 the disease was eradicated.

Publications:
An Inquiry into the Cause and Effects of the Variolae Vaccinae, a Disease Discovered in Some of the Western Counties of England, Particularly Gloucestershire, and Known by the Name of the Cow-pox (London, 1798)
Further Observations on the Variolae Vaccinae or Cow-pox (London, 1799)
A Continuation of Facts and Observations Relative to the Variolae Vaccinae or Cow-pox (1800)
A Complete Statement of Facts and Observations Relative to the Cow-pock, Thomas Paytherus, Edward Jenner, & William Woodville (London, 1800)
On the Origin of Vaccine Innoculation (London, 1801)
On the Varieties and Modifications of the Vaccine Pustule, Occasioned by an Herpetic State of the Skin (Cheltenham, 1806)
A Letter to C.H. Parry, MD, on the Influence of Artificial Eruptions in Certain Diseases Incidental to the Human Body (London, 1822)
Observations on the Migration of Birds (1823)

Publications by Others about Jenner:
The Life of Edward Jenner, John Baron (London, 1838)
Monument a Edward Jenner; Ou, Histoire Generale de la Vaccine a l'Occasion du Premier Centenaire de son Invention, Adolphe Pierre Burggraeve (Brussels, 1875)
Edward Jenner and the Discovery of Smallpox Vaccination, Louis Harry Roddis (Menasha, Wisconsin, 1930)
The Note-book of Edward Jenner in the Possession of the Royal College of Physicians of London, with an Introduction on Jenner's Work as a Naturalist by F. Dawtrey Drewitt, Frederick Dawtrey Drewitt (London, 1931)
Edward Jenner, Conqueror of Small Pox, Boswell Taylor (London, 1950)
A Bio-Bibliography of Edward Jenner, 1749-1823, William Richard LeFanu (London, 1951)
Dr Jenner of Berkeley, Dorothy Fisk (London, 1959)
Jenner and the Miracle of Vaccine, Edward F. Dolan, Jr. (New York, 1960)
Edward Jenner and Vaccination, Anthony John Harding Rains (London, 1974)
Edward Jenner's Cowpox Vaccine: The History of a Medical Myth, Peter Razzell (Firle, Sussex, 1980)
Letters of Edward Jenner and Other Documents Concerning the Early History of Vaccination, from the Henry Barton Jacobs Collection in the William H. Welch Medical Library, Genevieve Miller (ed.) (Baltimore, 1983)
Edward Jenner, Charles Bruce Perry ([Bristol] [1984?])
Edward Jenner, 1749-1823, Richard B. Fisher (London, 1991)
The Eradication of Smallpox: Edward Jenner and the First and Only Eradication of a Human Infectious Disease, Herve Bazin (San Diego, 2000)

Robert Lee was born in Melrose, Roxburghshire, in 1793, the second son of John Lee. He was educated in the Scottish Border town of Galashiels, under the Rev. Robert Balmer, the profound theologian. Lee entered Edinburgh University in 1806. Initially intended for the church he changed his mind and chose to pursue a career in medicine. He graduated MD in 1814, and became a member of the Edinburgh College of Surgeons. He was appointed physician's clerk at the Royal Infirmary to Dr James Hamilton, physician and professor of midwifery.

In 1817 Lee moved to London and took charge of an epileptic patient, the son of the Honorable William Lamb (afterwards Lord Melbourne). On relinquishing this appointment he spent the winter of 1821-22 in Paris, furthering his medical education through the study of anatomy. He remained abroad for the following year, employed as domestic physician to a family of high rank. He traveled with them through the South of France and Northern Italy. On his return to England he became a licentiate of the Royal College of Physicians of London, in March 1823, and began to practice as an obstetric physician.

He suffered a severe illness at this time. When he recovered he obtained a medical appointment with the East India Company. However, before leaving for Calcutta, he received the offer of appointment as domestic physician to Prince Woronzow, then governor-general of the Crimea and the Russian provinces around the Black Sea. He left for Odessa in October 1824. In 1825 he traveled with the Prince and his family to the Crimea, where he was presented to Czar Alexander a few days before the Czar's sudden death from epidemic fever. Lee later published an account of the Czar's final days, Last Days of Alexander and the First Days of Nicholas (1854), in order to counteract rumours that the Czar had died a suspicious death.

Lee returned to England with Prince Woronzow in 1826, and again began to practice as an obstetrician in London. In 1827 he was elected physician to the British Lying-in Hospital, and began to lecture on midwifery. In 1829 he also became lecturer on midwifery in the Webb Street School of Anatomy and Medicine. He had taught himself shorthand and this enabled him to make full notes of every lecture he attended and the cases he treated, making it possible for him to preserve written histories of the important cases of puerperal and uterine disease he came across after these appointments.

From his settling in London in 1827, Lee devoted much time and effort to investigations into the pathology of the diseases of women, puerperal fever, and in prolonged dissections of the ganglia and nerves of the uterus. He contributed to the Cyclopaedia of Practical Medicine (1833-35), writing entries on 'Abortion', 'Diseases of the Ovaries', 'Puerperal Fevers', 'Pathology of the Uterus and its Appendages', and 'Diseases of the Veins'. He also wrote numerous papers. Many were published in the Transactions of the Royal Medical and Chirurgical Society, whilst others he read before the Royal Society. He was elected Fellow of the Royal Society in 1830. Despite Lee's proliferation of papers the Society never awarded him a medal and even suppressed some of his articles. This was due, it is said, to `differences of opinion as to the value of his discoveries' (DNB, 1892, p.373).

He became secretary to the Royal Medical and Chirurgical Society, 1830-35. In 1834 he obtained, through the interest of Lord Melbourne, the appointment of Regius Professor of Midwifery at the University of Glasgow. However he resigned after his introductory address and returned to London. In 1835 he was appointed lecturer on midwifery and the diseases of women at St George's Hospital, an appointment he held for thirty years. Lee was admitted a Fellow of the Royal College of Physicians in 1841.

In 1842 he published what some consider his most valuable contribution, Clinical Midwifery (2nd ed. 1848), which contained 545 cases of difficult labour. His subsequent work, Three Hundred Consultations in Midwifery (1864) was also deemed to be important (ibid). However, others consider that it was his remarkable' dissections of the nerves of the heart and uterus thatentitle him to a place in the foremost rank of anatomists and physiologists of his time and country' (Munk's Roll, 1878, p.268).

Lee's relationship with the Royal Society did not improve in the 1840s. It was owing in part to his dissension that the president, the Marquis of Northampton, and the secretary, Dr Peter Mark Roget, resigned in 1849. Lee's version of his treatment by the Royal Society can be found in his Memoirs on the Ganglia and Nerves of the Uterus (London, 1849). Although it was recognized that Lee could be somewhat dictatorial in manner and intolerant of those in slightest opposition to his views, his honesty of purpose in all he did was never doubted' (ibid). Furthermore, he was undoubtedlyan indomitable worker, and made numerous discoveries of permanent value' (DNB, p.373)

He delivered several of the eponymous lectures of the Royal College of Physicians, namely the Lumleian Lectures in 1856-57, the Croonian Lectures in 1862, and the Harveian Oration in 1864, the last time the lecture was delivered in Latin. He resigned his lecturership at St George's Hospital in 1866, but continued in practice.

Lee worked indefatigably until 1875 when he retired from practice at the age of 82. He moved from his home in Savile Row to Surbiton Hill, Surrey, and died there on 6 February 1877. He was buried at Kensal Green.

Publications:
On the Structure of the Human Placenta, and its Connection with the Uterus (London, 1832) Researches on the Pathology and Treatment of the Diseases of Women (London, 1833)
Pathological Observations on the Diseases of the Uterus, with Coloured Engravings from Original Drawings by Joseph Perry, Representing the Most Important Organic Diseases of the Uterus (London, 2 parts 1840; 1849)
The Anatomy of the Nerves of the Uterus (London, 1841)
Clinical Midwifery, with the Histories of the Four Hundred Cases of Difficult Labour (London, 1842; 2nd edition 1848)
On the Ganglia and Other Nervous Structures of the Uterus (London, 1842)
Lectures on the Theory and Practice of Midwifery, delivered in the Theatre of St George's Hospital (London, 1844)
Memoirs on the Ganglia and Nerves of the Uterus (London, 1849)
Memoir on the Ganglia and Nerves of the Heart (London, 1851)
Clinical Reports of Ovarian and Uterine Diseases, with Commentaries (London, 1853)
The Last Days of Alexander, and the First Days of Nicholas, Emperors of Russia (London, 1854)
Treatise on the Employment of the Speculum in the Diagnosis and Treatment of Uterine Diseases (London, 1858)
Engravings of the Ganglia and Nerves of the Uterus and Heart (London, 1858)
Three Hundred Consultations in Midwifery (London, 1864)
History of the Discoveries of the Circulation of the Blood, of the Ganglia and Nerves, and of the Action of the Heart (London, 1865)
A Treatise on Hysteria (London, 1871)
Entries in Cyclopaedia of Practical Medicine (London, 1833-35), ed. by Sir John Forbes, John Conolly, & Alexander Tweedie

Publications about Lee:
Extracts from the Diary of Dr Robert Lee, FRS, 1821-22 (London, 1897, privately printed - posthumously)

Thomas Marwood was physician to James I. Dr William Munk, who made an exhaustive study of the manuscript doubted the authorship of Dr Marwood, and rather favoured the suggestion that 'the volume is really neither more nor less than the daily entry book of a leading and fashionable Apothecary in London, containing the copies in extenso of the prescriptions he compounded for the physicians who patronised and the persons who employed him. He may even have been 'Apothecary to the Person.' As such he would have been in immediate attendance on the king, as glysters and cupping had to be employed. Or lastly, the report of the illness and of the post-mortem examination may have been merely copied by the writer of the volume from the notes of one of the many physicians who were present throughout. It is clear that the author of the report was a medical man, and one thoroughly conversant with the habits of the king and the king and the whole course of his illness'.

Gavin Milroy was born in 1805, in Edinburgh, the son of a silversmith. He was educated at the Royal High School, Edinburgh, before entering the city's university to study medicine. He qualified licentiate of the Royal College of Surgeons of Edinburgh in 1824, and graduated MD from the university in 1828. He was a founder member of the Hunterian Society of Edinburgh.

Rather than enter into practice, Milroy enlisted as a medical officer in the Government Packet Service to the West Indies and the Mediterranean. On his return he was attracted to medical journalism, and from 1844-47 was co-editor of the Medico-Chirurgical Review. Milroy's detailed commentary on a French report on `Plague and Quarantine' was published in the Review in October 1846. In the article he advocated the abolition of quarantine, and the dependence on sanitary measures alone for protection from foreign diseases. Milroy was consequently acknowledged as an expert on epidemiology and was employed on several Government commissions of inspection and enquiry. From 1849-50 he acted as a superintendent medical inspector of the General Board of Health. Milroy was a member of the Medical and Chirurgical Society, and played an active role in establishing the Epidemiological Society of London in 1850.

In 1852 he went to Jamaica for the Colonial Office, to investigate a cholera epidemic. He presented to the authorities a report which charted the origin and progress of the epidemic, gave details of the social conditions of the natives, and made recommendations for sanitary measures. In 1853 he was elected fellow of the Royal College of Physicians. For the next two years, 1853-55, he was again medical inspector for the General Board of Health. From 1855-56, during the Crimean War, he served on the Sanitary Commission inspecting the British troops in the field. The reports, written by Milroy and his colleague John Sutherland, from the Board of Health, did influence subsequent reforms, although at the time the Army Medical Department had insufficient authority to institute the necessary changes.

In 1858 Milroy was honorary secretary of a committee appointed by the National Association for the Promotion of Social Science to enquire into the question of quarantine worldwide. As secretary Milroy assimilated and digested the results, and communicated them to the Board of Trade. The committee's findings were incorporated into three parliamentary papers, 1860-61. The papers contained information not only on the laws and practice of quarantine, but also on the appearance and prevalence of the diseases for which quarantine was being imposed throughout the world. Milroy was secretary of the Epidemiological Society, 1862-64, and then its president, 1864-66.

Milroy was a member of the committee of the Royal College of Physicians, appointed at the request of the Colonial Office in 1862, to examine the spread of leprosy. The committee's report of 1867 included an appendix by Milroy giving suggestions, entitled Notes respecting the Leprosy of Scripture'. Other contributions to medical literature included the article onPlague' in Sir John Russell Reynold's System of Medicine (1866-79), many articles for The Lancet, and many other anonymous articles in various medical journals. It has been said of Milroy that he was `a modest, unassuming man, of sound judgment, and considerable intellectual powers' (DNB, 1894, p.23). In 1871 Milroy was awarded a civil list pension of £100 a year by the Government.

In later years he lived at Richmond, Surrey. His wife Sophia (nee Chapman) died about three years before her husband. Milroy died at Richmond on 11 January 1886, and was buried in Kensal Green Cemetery. He bequeathed to the College £2,000 to found the Milroy Lectureship on state medicine and public health, and accompanied the bequest with a memorandum of suggestions.

Publications:
Quarantine and the Plague, being a Summary of the Report on these Subjects recently addressed to the Royal Academy of Medicine in Paris, with Introductory Observations, Extracts from Parliamentary Correspondence, and Notes (London, 1846)
Abstract of Regulations in Force in Foreign Countries respecting Quarantine (Parliamentary Papers no.568, 25 August 1860); Abstracts of Information concerning the Laws of Quarantine (Parliamentary Papers no.568-1, 21 August 1860); Papers relating to Quarantine (Parliamentary Papers no.544, 6 August 1861)

Sir Alexander Morison was born on 1 May 1779 at Anchorfield, near Edinburgh. He was educated at the city's high school, and then proceeded to the University of Edinburgh where he spent five years. He studied medicine under the eminent surgeon Alexander Wood, who was at the time head of the surgical profession in Edinburgh. He graduated MD on 12 September 1799. His thesis was entitled `De Hydrocephalo Phrenitico', and he continued to take a special interest in cerebral and mental diseases throughout his life.

Morison became a licentiate of the Edinburgh College of Physicians in 1800, and a fellow in 1801. He practiced medicine in Edinburgh for a time before, in 1808, moving to London. In the same year he became a licentiate of the Royal College of Physicians of London. Morison devoted his attention particularly to insanity. He was appointed inspecting physician of lunatic asylums in the county of Surrey in 1810. For many years he gave an annual course of lectures on mental diseases and became recognised as an expert in this field.

In 1826 he published Outlines of Lectures on Mental Diseases, and two years later, Cases of Mental Disease, with Practical Observations on the Medical Treatment (1828). In 1835 he became physician to the Bethlehem Hospital. He was also physician to Princess Charlotte and to Prince Leopold. He was knighted in 1838.

In 1840 Morison published The Physiognomy of Mental Diseases. His publications were brief but were illustrated with a large series of portraits of lunatics. He was elected a fellow of the Royal College of Physicians in 1841.

Morison died in Edinburgh on 14 March 1866, aged 86, and was buried at Currie.

Publications:
Outlines of Lectures on Mental Diseases (London, 1826)
Cases of Mental Disease, with Practical Observations on the Medical Treatment (London and Edinburgh, 1828)
The Physiognomy of Mental Diseases (London, 1840)

Possibly Joseph Phelan, MD Glasgow 1785, LRCP 1786, naval surgeon.

Born, 1707; education: St Andrews; St Leonard's College, 1722; Edinburgh University, 1727; studied medicine in Leiden, graduating MD, 1730; completed his medical studies in Paris; medical practice in Edinburgh; joint Professor of Pneumatics (metaphysics) and Moral Philosophy in Edinburgh University; Physician to the Earl of Stair; Physician to the Army in Flanders, 1742; Physician-General to the Duke of Cumberland, 1744-1748; resigned his professorship in Edinburgh, 1744; settled in London and continued in medical practice, 1748; Physician-in-Ordinary to the Duke of Cumberland, 1749; Council member of the Royal Society, 1753; LRCP, 1758; FRCP, 1763; speciali gratia, Physician to the Queen, 1761; President of the Royal Society, 1772-1778; baronet, 1766; gazetted Physician-in-Ordinary to the king, 1774; died, 1782.

Publications:
Observations on the Nature and Cure of Hospital and Jayl Fevers (1750)

Observations on the Diseases of the Army (1752)

Born, 1862; educated at Maclaren's School at Summerfield, Oxford, and at Marlborough College; medical student at St Bartholomew's Hospital, London, 1881-1883; St John's College, Cambridge, 1883-; Demonstrator in Pathology at Cambridge, 1887; House Physician at St Bartholomew's; Demonstrator in Anatomy at St Bartholomew's; Curator of the museum at St George's Hospital, London, 1890; MD, 1891; Assistant Physician to St George's, 1893; Physician to St George's, 1898-[1918]; staff of the Victoria Hospital for Children, London; Fellow of the Royal College of Physicians, 1894; Consulting Physician to the Imperial Yeomanry Hospital at Pretoria, South Africa, 1901; served on advisory committees set up by the Royal Army Medical Corps and the Royal Naval Service to improve the conditions of its officers; examiner for the service's entrance and promotion examinations in medicine; consulting physician to the Royal Navy, with the temporary rank of surgeon rear-admiral, First World War; representative of the medical department of the Admiralty on the medical board of the flying corps, and he became Physician to the Central Flying Hospital at Mount Vernon, Hampstead, London, 1917-1919; Consulting Physician to St George's Hospital, 1918; Consulting Physician to the Ventnor Hospital for Consumption on the Isle of Wight, 1922; Consulting Physician to the King Edward VII Sanatorium at Midhurst, 1923; Physician-in-Ordinary to King George V, 1923; President of the Royal Society of Medicine, 1918-1920; President of the Royal College of Physicians, 1922-1926; President of the Association of Physicians of Great Britain and Ireland, 1925 and 1929; President of the Medical Society of London, 1926-1927; Regius Professor of Physic at Cambridge, 1925; retired, 1932; died, 1944.

Born, 1751; educated University of Edinburgh; surgeon's mate on one of the East India Company's ships, 1766; assistant surgeon on the Company's Madras establishment; General Hospital at Madras; practised botany in his spare time; full surgeon, 1780; stationed at Samulcotta, 1781; naturalist in the Madras Presidency, 1790; Superintendent, Royal Botanic Garden in Calcutta, 1793-1813; returned to England, 1813; died, 1815.

John Snow was born on 15 March 1813 in York, the eldest son of William Snow, farmer. He was educated locally at a private school, until the age of fourteen when he was apprenticed to William Hardcastle, a surgeon in Newcastle-upon-Tyne. In Newcastle he worked as one of three surgeon apothecaries at the Lying-In Hospital, where he was also secretary. He also held an appointment as mining doctor at the Killingworth Colliery. This work brought him into contact with George and Robert Stephenson, who in 1827 were listed as patients of his practice. Throughout the Cholera epidemic of 1831-32 he attended victims at the colliery. During his apprenticeship, 1827-1833, he became a vegetarian and teetotaler.

Between 1833 and 1836 he was an assistant in practice, first in Burnopfield, Durham, and then in Pateley Bridge, North Yorkshire. During this time he often returned to York and was much involved in the temperance movement. In 1836 Snow decided to further his medical education in London. He undertook the journey on foot, walking via Liverpool, Wales and Bath. In October 1836 he became a student at the Hunterian School of Medicine, Great Windmill Street, where his initial research in medicine began, the subject being the toxicity of arsenic. In October 1837 he began to attend the medical practice at the Westminster Hospital. He was admitted a member of the Royal College of Surgeons of England on 2 May 1838, and in October of that year he became a licentiate of the Society of Apothecaries.

Snow set up practice in his new home at 54 Frith Street from 1838. To further his medical knowledge Snow regularly attended the meetings of the Westminster Medical Society (later the Medical Society of London), having joined as a student member in 1837. He presented the results of his research on a number of diverse scientific problems at the Society's meetings, and subsequently published articles on them in the medical journals, throughout the late 1830s and early 1840s. The two dominant themes were toxicology and respiratory physiology. His first published paper, Arsenic as a Preservative of Dead Bodies', appeared in The Lancet in 1838. However, his most well known paper was published in 1842, On Asphyxia, and on the Resuscitation of Still-born Children. Other topics included the danger of candles incorporating arsenic, postscarlatinal anasarca, and haemorrhagic smallpox. By the end of this phase of his career,the name of John Snow was quite well known to anyone who read the English Medical Press' (Shephard, 1995, p.44).

He graduated MD from London University on 20 December 1844, having graduated MB in November 1843. At this time, after the immense pressure of hard work, he had a breakdown and it is thought suffered an attack of tuberculosis (Fraser, 1968, p.504). His health was further affected during the following year when he suffered from renal disease. It was in 1845 that he was appointed lecturer on forensic medicine at the Aldergate Street School of Medicine, a position he held until 1849 when the school closed.

In 1846 Snow became interested in the properties of ether, which had been newly adopted in America as an anaesthetizing agent. His work in anesthesia had begun during his earlier investigation into asphyxia of the newborn. Snow made great improvements in the method of administering the drug, and obtained permission to demonstrate his results in the dental out-patient room at St George's Hospital. This proved so successful that he won the confidence of Robert Liston, the eminent surgeon, and so the ether practice of London came entirely into his hands. Despite having practically introduced the scientific use of ether into English surgery, he had `so well balanced a mind that he appreciated the value of other anaesthetizing agents, more particularly chloroform' (DNB, 1898, p.208). It was this drug that he famously administered to Queen Victoria during the birth of Prince Leopold, 7 April 1853, and again, a few years later, during the birth of Princess Beatrice, 14 April 1857.

Snow is famous for his scientific insight which led to the theory that cholera is communicated by means of a contaminated water supply. His essay On the Mode of Communication of Cholera, was first published in 1849. The second edition, in 1855, included a more elaborate investigation into the effect of the water supply on certain districts of South London during the 1854 epidemic. Ultimately then Snow became

`widely recognised as one of the founding fathers of epidemiology as well as a leading figure in the initial development of anaesthetics in Britain' (Galbraith, 2002, p.1).

During the intervening years between the two editions of his publications on cholera, Snow was admitted as a licentiate of the Royal College of Physicians and was a founder member of council of the Epidemiological Society of London, in 1850. In 1852 the Medical Society of London selected him orator for the following year. It was also in 1853 that he moved home and practice to 18 Sackville Street. He was a member of the Royal Medical Chirurgical Society and the Pathological Society, and was President, in 1854 of the Physiological Society, the Medical Society of London in 1855, and in 1857 of the Epidemiological Society.

Snow died unmarried, at the age of 45, on 16 June 1858. The direct cause of death was a stroke, however the autopsy revealed his health for many years had been undermined by the earlier attacks of tuberculosis. He was engaged on his work, Chloroform and Other Anaesthetics, at the time of his death. This was edited and published posthumously by his friend and fellow physician Sir Benjamin Ward Richardson. Snow was buried at Brompton Cemetery, where his colleagues and friends erected a monument in his memory.

Publications:
`On Distortions of the Chest and Spine in Children from Enlargement of the Abdomen', London Medical Gazette, 1841, 28, pp.112-116
On the Inhalation of the Vapour of Ether in Surgical Operations (London, 1847)
A Letter to the Right Honorable Lord Campbell, Lord Chief Justice of the Court of Queen's Bench, on the Clause Respecting Chloroform in the Proposed Prevention of Offences Bill (London, 1851)
On the Mode of Communication of Cholera (London, 1849, 2nd ed. 1855) - translated into German, Quedlinburg, 1856
On Chloroform and Other Anaesthetics, John Snow, edited with a memoir, Benjamin Ward Richardson (London, 1858)
On Narcotism by the Inhalation of Vapours, John Snow, with an introductory essay by Richard H. Ellis (London, 1991)
Death from Amylene (date & place of publication unknown)

Publications by others about Snow:
Memoir by B.W. Richardson in On Chloroform and Other Anaesthetics, John Snow, edited by Benjamin Ward Richardson (London, 1858)
Dr John Snow (1813-1858): His Early Years: An Account of the Family of Dr John Snow and his Early Life, Dr Nicol Spence Galbraith (London, 2002)

Born, 1871; education: Market Harborough Grammar School; Wycliffe College, Stonehouse; Firth College, Sheffield; Guy's Hospital; University of Heidelberg. Physician St George's Hospital, 1904-1913; Dean of the Medical School; Physician to Victoria Hospital for Children; London Chest Hospital; Demonstrator of Physiology, Guy's Hospital, 1898-1904; Captain, Royal Army Medical Corps; left London for Scotland where he conducted Duff House, Banff clinic, 1913-1922; Honorary Medical Advisor to Ministry of Food, 1917-1918; Senior Physician, Ruthin Castle Clinic, 1922-1944; High Sheriff for County of Denbigh, 1945-1946; Consulting Physician; died, 1949.

Unknown

Born, 1850; degree of DSc, London, 1884; graduated in medicine at the Victoria University, Manchester; 1889; Diploma of Public Health of the University of Cambridge, 1892; MD, 1896; first Medical Officer of Health for the County of Essex; Consulting Medical Officer; Lecturer in Public Health at the London Hospital Medical College; Examiner in State Medicine for the University of London; one of the early pioneers who established the importance of hygiene in connection with the home; died, 1932.

John Warburton attended Caius College Cambridge and was a Member of the Royal Medical Society Edinburgh. He died, 1843.

Born, 1828; educated at Kensington grammar school and The Grange, Sunderland; earnt his living by teaching, first at Glasgow and than at the Royal Institution, Liverpool; attended St John's College, Cambridge, 1848-1852; second master of Bristol grammar school, 1852; headmaster, 1855; resigned his post at Bristol grammar school, 1860; opened a private school at Manilla Hall, Clifton, 1861-1881; devoted his leisure to microscopical research, in particular the study of the Rotifera; fellow of the Royal Microscopical Society, 1872; president of the Royal Microscopical Society, 1888-1890; Fellow of the Royal Society, 1889; died, 1903.

Originally set to the family trade of broadcloth weaving, Canton's learning and mechanical talent, as shown by his creation of an accurate sundial proudly displayed outside the house by his father, brought him to the attention of Dr Henry Miles (Fellow of the Royal Society, 1843). Miles persuaded Canton's father to allow John to reside with him in Tooting, Surrey, until 1738, when John articled himself to Samuel Watkins, master of a school in Spital Square, London, whom he succeeded as master and owner of the school until his death in 1772. Canton's first contributions to science were routine calculations of the times of lunar eclispes, published in the Ladies Diary for 1739 and 1740. Through Miles he met London's best 'experimental philosophers' such as the apothecary William Watson and clockmaker John Ellicott. He rapidly acquired the same reputation, largely for his invention of a new method of making strong artificial magnets. He kept the method secret, hoping to make some income from it, until the publication of John Mitchell's A Treatise of Artificial Magnets (1750). His procedure appeared very similar to Mitchell's, who immediately accused him of plagiarism. This did not prevent the Royal Society from awarding him the Copley Medal for 1751; Canton had a method before Mitchell's publication, and from what is known of his character testifies to his innocence. In 1752 Canton learned of the French experiments confirming Franklin's conjecture about lightning. He was the first in England to repeat the experiments successfully, and in the process discovered independently that clouds came electrified both positively (as theory suggested) and negatively. His work on determining the sign of a cloud's charge led Canton to design the well known experiments on electrostatic induction which have earned him a place in the history of electricity. He also made the notable discovery that glass does not always charge positively by friction; the sign of the electricity developed depends upon the nature of the substance rubbed over it and the condition of the surface of the glass. Other contributions to the subject were a portable pith-ball electroscope (1754), a method for electifying the air by communication (1754), a careful account of that bewildering stone the tourmaline (1759) and an improvement in the electrical machine, coating its cushion with an amalgam of mercury and tin (1762). As a gifted amateur physicist of his time, Canton displayed interest in other topics, such as identifying the cause of the luminosity of seawater (putrefying organic matter); invented a strongly phosphorescent compound 'Canton's phosphor' made of sulphur and calcined oyster shells (CaS); kept a meteorological journal; recorded the diurnal variations of the compass; and demonstrated the compressibility of water, a notable achievement, which depended on measurements so minute he was challenged on his revolutionary interpretation of them, although they stood the scrutiny of a special committee of the Royal Society and earned him a second Copley Medal in 1765. He was a frequenter of the Club of Honest Whigs in the company of Franklin and Dissenting Ministers like Joseph Priestley, whose History and Present State of Electricity owed much to his patient assistance. Canton was one of the most distinguished of the group of self-made, self-educated men who were the best representatives of English physics in the mid-eighteenth century.

Paulus Orosius was a Christian historian, theologian and disciple of St. Augustine who came from Gallaecia. He wrote Historiarum Adversum Paganos Libri VII ("Seven Books of History Against the Pagans"), which he wrote in response to the belief that the decline of the Roman Empire was the result of its adoption of Christianity.

William Scoffin was Captain of the Arctic Whaler Duncombe.

Robert Boyle was born on 25 January 1627 at Lismore, Munster, seventh son of the notorious Richard Boyle, first Earl of Cork, thereby having high status and considerable wealth. His education began at home, then continued at Eton and with foreign travel from 1639. He visited France, Geneva - where he suffered a conversion experience which was to have a profound effect on him - and Italy, where he discovered the writings of Galileo. He returned to England in 1644, taking up residence at the family manor of Stalbridge, Dorset, from 1645. He visited Ireland in 1652-1653, then by 1656 moved to Oxford where he joined the circle of natural philosophers there which formed the liveliest centre of English science at that time. After the Restoration in 1660, many of them moved to London, where the Royal Society was founded (with Boyle among its founding Fellows), although Boyle did not move there until 1668, sharing a house in Pall Mall with his sister Katherine, Lady Ranelagh, until they both died in 1691. In the 1640's he became preoccupied with themes which were to continue throughout his life - vindication of an approved understanding of nature, in its own right as well as its utilitarian advantages; insistence on the importance of experiment in pursuing this aim, and the advocacy of spirituality. To these ends he became involved with other like-minded individuals known as the 'Invisible College', and subsequently the circle of intellectuals surrounding the Prussian emigré, Samuel Hartlib. He devoted his life to extensive and systematic experimentation, and to writing. His major scientific work on pneumatics, 'New Experiments Physico-Mechanical, Touching the Air and its Effects', used the air pump as the key piece of equipment used to explore the physical properties of air, vindicated the possibility of a vacuum, illustrated the extent to which life depended on air, and proved that the volume of air varies inversely with its pressure (Boyle's Law). 1661 saw the publication of the 'Sceptical Chemist' and 'Certain Physiological Essays', the beginning of a series where he sought to vindicate a mechanistic theory of matter and to remodel chemistry along new lines, and where he crucially vindicated an experimental approach. In the 1670's his publications continued the previous themes, but also included theology. In the 1680's, his interest shifted to medical matters, such as 'Memoirs for the Natural History of Human Blood' (1684), or the collections of recipes in his 'Medicinal Experiments' (1688-1694). At the same time, he continued his work as a Christian apologist, his 'The Christian Virtuoso' appearing in 1690. His concern about the theological implications of the new philosophy can be seen in 'Discourse of Things above Reason' (1681) and 'Disquisition about the Final Causes of Things' (1688). On his death in 1691 he endowed a Lectureship to expound the Christian message. His significance to the development of natural philosphy was recognised in his lifetime, and his influence was particularly important for Isaac Newton, the leading figure in the following generation, whose work is seen as the culmination of the scientific achievement of seventeenth-century England.

Born, 1825; PhD; Professor of Chemistry, Owen's College, Manchester, -1857; Fellow of the Royal Society, 1853; Royal Medal, 1857; Copley Medal, 1894; Secretary of the Royal Society, 1895-1899; Vice President of the Royal Society, 1887-1888; died, 1899.

Botanical collection begun in Yorkshire c 1833; specialized in mosses and liverworts, an interest confirmed after a visit to Dr Thomas Glanville Taylor in Ireland in 1848. Came to the attention of Sir William Hooker in 1844 and sent to the Pyrenees on an expedition (1845-6) under the sponsorship of George Bentham. Hooker, Bentham and other botanists sent Spruce to South America in 1849. At the end of that year he travelled up the Amazon to Santarem where he met zoologist Alfred Russel Wallace and lepidopterist Henry Walter Bates. His exploration at this date included plants with medicinal properties, such as the datura and coca plants. He spent three years on the Orinoco and Negro rivers, then in 1854 ascended the Amazon by steamer to Nantua in Peru and then to the Andes, where he stayed two years and collected 250 species of ferns. In 1857 he came down the Amazon and went to Ecuador, later moving to Ambato which he made his headquarters and explored the Quintensian Andes. The India Office commissioned him to collect seeds and polants of the cinchona, the source of quinine, which were later sent to India. He published his report on this in 1861. In 1867 he finally returned to England and spent the remaining twenty seven years of life sorting his collections. These included notes on twenty one Amazonian languages, many hundreds of drawings, and notes and maps of three previously unexplored rivers.

Born, 1635; Education: Queen's College, Oxford; BA (1655), DCL (1677); Lincoln's Inn (admitted 1654); Career: Travelled abroad (1659-1661); Original Fellow of the Royal Society, 1663; Clerk to the Commission of Prizes (1664-1667); Clerk to the Privy Council (1664-1679); Deputy Vice-Admiral of the Provinces of Munster (1665), Vice-Admiral (1677); Envoy extraordinary to Portugal (1665-1669), Flanders (1671-1672) and to the Elector of Brandenburg (1680); Chief Commissioner of Excise (1671-1681); Commissioner for Assessment for Middlesex (1673-1680, Westminster (1677-1680), Gloucestershire (1679-1680, 1689-1690); MP for Penrhyn (1673-1679), Lostwithiel (1685-1687); Commissioner of Customs (1689-1697); Deputy-Lieutenant of Gloucestershire (1689-1694); Principal Secretary of State for Ireland (1690-1702); Privy Councillor, Ireland (1690-death); endowed an almshouse for eight helpless men and women on his estate at Dromderrick, Kinsale (1682); died, 1702.

Born, 1646; Education: Derby School; Jesus College, Cambridge; MA (Lit. Reg. 1674)
Career: Left school because of an attack of rheumatism (1662); travelled to Ireland in search of a cure; went to London (1670) where he met Henry Oldenburg (FRS date) and Sir Jonas Moore (FRS date), who became his patron; ordained (1675); first Astronomer Royal (1675-1719), he used his own instruments, which were removed by his widow after his death; Vicar of Burstow, Surrey (1684); a perfectionist, he was reluctant to publish his observations unless they were perfect, which led to conflict with Newton and Halley. On 12 December 1709 Queen Anne appointed a Board of Visitors of the Royal Observatory made up of the President and Council of the Royal Society, authorizing them to demand a copy of each year's observations, to direct what observations should be made, and to examine the observatory's instruments. Flamsteed's vigorous objections and refusal to co-operate further on the publication of his star catalogue and observations led to an incomplete version being published by Halley in 1712, which he condemned. After the accession of George I Flamsteed was able to buy up 300 of Halley's unsold copies, and after removing the sextant observations which he had previously approved and reserving some copies to display their errors, he burnt the rest. His observations were published to his very high standards posthumously in 1725 edited by his wife Margaret, and his 'Atlas Coelestis' in 1729, where the editor was again his wife with Crosthwait and Sharp responsible for the technical side; died, 1719.

David Gregory of Kinnairdie (1627-1720), inventor, apprenticed by his father to a mercantile house in Holland. Returned in 1655, and succeeded to the estate of Kinnairdie on the death of an older brother. Highly regarded in medicine, having a large gratuitous practice both among the poor, and people of standing. First man in Aberdeenshire to possess a barometer, and his weather forecasts exposed him to suspicions of witchcraft. Moved to Aberdeen and investigated artillery. With help of an Aberdeen watchmaker constructed an improved model of a cannon, forwarding it to his eldest son David , and to Newton, who held it was 'for the diabolical purpose of increasing carnage', and who urged him to break it up.

David Gregorie (1661-1708, FRS 1692), astronomer, son of David Gregory (1627-1720). Professor of Mathematics at Edinburgh University in 1683, first professor to lecture publicly on Newtonian philosophy, enthusiastic promoter of Newton's 'Principia'. In 1691 went to Oxford where introduced to Newton, who became an intimate friend and who with Flamsteed influenced his appointment as Savilian Professor of Astronomy in Oxford. His principal work 'Astronomiae Physicae et Geometricae Elementa' in 1702 was the first text book composed on gravitational principles and remodelling astronomy in conformity with physical theory. Approved by Newton, who had included in it his lunar theory, and for which he wrote a preface. Gregory was a skilful mathematician who left manuscript treatises on fluxions, trigonometry, mechanics and hydrostatics, and who was also known for his printing in 1703 of all the writings attributed, with any show of authority, to Euclid.

James Gregory (1638-1675, FRS 1668) mathematician and elder brother of David Gregory (1627-1708) His scientific talent was discovered and encouraged by his brother, and in 1673 at age 24 he published his 'Optica Promota' containing the first feasible description of a reflecting telescope, his invention of it dating from 1661, and inspiring Newton to make his own reflecting telescope. Studied mathematics in Padua 1664-1667, publishing 'Vera Circuli et Hyperbolae Quadratura' in 1667, showing how to find the areas of the circle, elipse, and hyoerbole by means of converging series, and applying the same new method to calculation of logarithms. Friendly debate with Newton 1672-1673 as to merits of their respective telescopes. From 1674 first exclusively mathematical professor at Edinburgh.

Charles Gregory was one of the 32 children of David Gregory (1627-1720) and brother of the second David Gregory (1661-1708).

Born, 1635; Education: Queen's College, Oxford; BA (1655), DCL (1677); Lincoln's Inn (admitted 1654); Career: Travelled abroad (1659-1661); Original Fellow of the Royal Society, 1663; Clerk to the Commission of Prizes (1664-1667); Clerk to the Privy Council (1664-1679); Deputy Vice-Admiral of the Provinces of Munster (1665), Vice-Admiral (1677); Envoy extraordinary to Portugal (1665-1669), Flanders (1671-1672) and to the Elector of Brandenburg (1680); Chief Commissioner of Excise (1671-1681); Commissioner for Assessment for Middlesex (1673-1680, Westminster (1677-1680), Gloucestershire (1679-1680, 1689-1690); MP for Penrhyn (1673-1679), Lostwithiel (1685-1687); Commissioner of Customs (1689-1697); Deputy-Lieutenant of Gloucestershire (1689-1694); Principal Secretary of State for Ireland (1690-1702); Privy Councillor, Ireland (1690-death); endowed an almshouse for eight helpless men and women on his estate at Dromderrick, Kinsale (1682); died, 1702.

Born in 1659 at Bushby, Leicestershire, educated at Merchant Taylors School, and elected in 1677 to St John's College Oxford where he developed an interest in botany. In 1683 he was elected a law Fellow of St John's College, and in 1694 received the degree of Doctor of Common Law. With the permission of the college, he began a series of foreign tours. He studied botany in Paris under Tournefort (1686-1688) and in 1688 spent time in Leiden with Paul Hermann. The plants he listed in the Swiss Alps, Geneva Roma and Naples were sent to Ray to publish in his 'Stirpium Europeaorum' of 1694, and those from Cornwall and Jersey in his 'Synopsis methodica Stirpium Britannicarum' of 1690. He wa a tutor to Sir Arthur Rawdon, living mainly at Moira, County Down, then tutor to Charles Viscount Townsend on his continental tour, and in 1695 to Wriothesley, eldest son of William Lord Russell in France and Italy. During this period he began his revision of Gaspard Bauhin's 'Pinax', a project which remained unfinished at his death. Until 1702 he was tutor to Henry, second Duke of Beaufort at Badminton. In 1702 he had a short appointment as Commissioner for the Sick and Wounded, and the Exchange of Prisoners, follwed in 1703 with his appointment by the Levant Company as Consul in Smyrna. Here he indulged his botanical and antiquarian interests, collecting plants, copying anitquarian artefacts and collected coins.In 1717 he returned to England a wealthy man. In 1718 he was elected a Fellow of the Royal Society, and served on the council for two years. He made three further trips to the continent, in 1721, 1723 and 1727, visiting Boerhaeve in Holland and bringing Dillenius back to asist him with the 'Pinax'. He had been hampered in this by a quarrel with Sir Hans Sloane, who refused him his herbarium, but a reconciliation took place in 1727. Sherard died in 1728, leaving his books, drawings and paintings, and his manuscript of 'Pinax' to the library of the 'Physic Garden' at Oxford, the rest to St John's College. In addition, he left £3000 to establish the Sherardian Chair of Botany, naming Dillenius the first Sherardian professor. Sherard occupied a high position among botanists of his time, although the only work he himself wrote was 'Schola Botanica' (1689).

Warren de la Rue was born, 1815; engineer who undertook research in chemistry and astronomy; FRS, 1850; Royal Medal, 1864; Vice President of the Royal Society, 1869-1870 and 1883-1885; died, 1889.

This Copy version was transcribed in the eighteenth century, possibly for reasons of security like the Journal Books and the Council Minutes. It is known that one volume of the Register was lost (Volume 2) and then recovered - but not before a replacement had been made, leaving three versions in total (Original, Duplicate and Copy). A further copy of the original Volumes 1and 2 was made (date unknown) and returned to the Society in 1814, being presented to Sir Joseph Banks (MSG/776). Volume 10 of the series does not exist - this was left as a deliberate gap in the sequence, to be filled if original papers became available for copying.

Amelia Fysh (nee Bullen) (born c 1922) was brought up in Grimsby. She won a scholarship to attend the local grammar school and during the war worked in the Royal Signal Corps as a cipher operator. At the end of the war she was working in the War Office in London. Before being demobilised she was recruited to teach young male recruits. After the end of the war she entered the teaching profession through completing the Emergency Training Scheme. Her first teaching role was a reception class of 50 children in a school in her home town. Appalled by the class sizes in primary schools she entered nursery education, running the nursery class at South Parade Primary School, also in Grimsby. During this time she completed the Child Development Diploma at the University of London, Institute of Education. In 1966 she gained a Certificate in Education of the Handicapped Child from the University of Leicester, School of Education.

In 1956 she became the Headteacher of Beech Green Nursery School in Aylesbury, Buckinghamshire, which had been opened in 1942 by the Save the Children Fund, initially for evacuees and the children of mothers working towards the war effort. When Amelia joined the nursery it was already inclusive in its nature but during her time there Fysh was a pioneer of learning through creating an environment that fostered creativity, outdoor play and inclusive education for children with learning and physical disabilities. During this time the nursery admitted fifty children with disabilities including Downs Syndrome, cerebal palsey, spina bifida, autism, epilepsy, and hearing and sight impairments. Many leaders from other playgroups visited Beech Green to talk to staff about their work and Amelia devised an eight week course regarding the work that had been completed at the nursery. She left the nursery school in 1972 to become a teacher trainer.

Amelia Fysh has been described as a champion of introducing educational inclusion, particularly for children with special needs, decades before the writing of the Warnock Report in 1978. She did not conform to one school of theory but drew on the work of a number of different academics including Jean Piaget, Susan Isaacs and Tina Bruce. Her main line of thought focused on the importance of the individuality of children. She stated a child's development could be stimulated through creative learning and important activities including water play, building materials, dressing up, role play, painting and cookery. Over a nine year period (1964-1973) she tracked the development of nursery years children through asking them to draw a man with felt-tip pen on a 6 inch by 9 inch piece of paper. No child was requested to complete a drawing and drawings were completed on regular (but not time specific) occasions. These works showed how a child's development was not linear. Amelia's work was published in 199[7] in 'Discovering Development with the 3-5s. A Longitudinal study 1964-1973'.

In more recent years Power Drawing, an education programme of the Campaign for Drawing, has encouraged teachers to follow the work of Amelia Fysh, and to retain a collection of the work created as evidence of their development. In 2003, aged 81 she worked for Buckinghamshire Local Education Authority (LEA), participating in their training provision on inclusion and special needs for nursery and child care providers.

Bernard Basil Bernstein (1924-2000) was educated at Christ's College, Finchley, London. After serving in the RAF during World War Two, he went on to study sociology at the London School of Economics, graduating in 1951. Meanwhile he also undertook social work, being a resident Settlement Worker at the Bernard Baron Settlement in Stepney, London, from 1947-1949, where he undertook family case work, youth club work, community organisation and participated in 'delinquent camps'. He went on to train as a teacher at Westminster Training College (1953-1954) and then taught a range of subjects at the City Day College, Golden Lane (1954-1960), becoming a Research Assistant at University College London (1960-1963) and obtaining a PhD from the University of London in 1963. From 1962 to 1967 Bernstein was a Reader in the Sociology of Education at the University of London Institute of Education, being Head of the Sociological Research Unit from 1962 and Professor in the Sociology of Education from 1967. From 1979 he was the Karl Mannheim Professor in the Sociology of Education at the Institute and from 1984 was Senior Pro-Director and Pro-Director Research. After his retirement in 1991 Bernsetin became an Emeritus Professor. He held honorary degrees from several different universities. Bernstein was influential in the field of socio-linguistics. His published works, in particular the five volumes of the series on Class, Codes and Control, have become classics in the field.

The British Families Education Service (BFES) was established by the Foreign Office in 1946 to provide schooling for the children of British families stationed in the British Zone of Germany after the Second World War, and amidst the post-War devastation. In the winter of 1951-1952 it was taken over by the Army and became Service Childrens' Education. The BFES Association was founded in 1967 to enable BFES teachers to keep in touch. In the 1980s it merged with the Service Childrens' Education Association (SCEA), which had changed its name to SCE, to become the BFES/SCE Association. It arranges annual reunions and publishes an annual magazine.

The National Association of Development Education Centres (NADEC) was formed as a network of local centres in the early 1980s, with a core staff of 2-3 people. In the 1980s, NADEC established a Joint Agencies Network (JAG) which was a youth work network. Later, at the end of the decade the Inter Agency Committee for Development Education, an informal network of development NGOs engaged in development education, was set up. This, in turn, established the National Curriculum Monitoring Project (NCMP), a lobbying network with a part-time worker for curriculum change. The Agency also discussed the setting up of a Global Education Network (GEN), a broader NGO network, but this never came to fruition. In 1993, NADEC became subsumed within the Development Education Association (DEA), taking JAG with it. Initial research for the DEA had been undertaken in 1991-1992 with funding from Rowntrees, and the Inter Agency Committee for Development Education became a joint founder. After the 1993 launch a Council (essentially a Board of Trustees) and various Sub Committees were set up. Plus, the DEA continued to control the network of about 50 Centres - a key part of Development Education history - independent local centres which had originally been accredited in terms of status by NADEC. The DEA held an AGM and a range of conferences from 1994 onwards and in 1997 a major expansion of organisation saw the establishment of DFID and development education funding from UK government. As a consequence, a significant youth work programme was established in the late 1990s around the theme of global youth work.

The Education in Human Rights Network was established in January 1987 to 'enable and encourage communication between people working in a variety of educational settings in promoting an awareness and understanding of human rights', as it was considered that human rights education was receiving little Government and DES support.

The Network acted as a channel for communication between organisations and those people working in education, especially teacher education. Its aims were:

1) To promote an understanding of human rights and responsibilities as fundamental values in a pluralist democracy and for the world community. To encourage knowledge of both the protection of human rights and abuses of human rights in the UK, in Europe and in other areas of the world. To affirm the importance of human rights as basic values in education, at work and in society.

2) To ensure that the spirit and the content of the Universal Declaration of Human Rights, the European Convention for the Protection of Human Rights and Fundamental Freedoms, and other major rights documents are known to teachers and to young people in schools.

3) To help implement in the UK the Recommendations of the Committee of Ministers of the Council of Europe 'On teaching and learning about human rights in schools'.

4) To work through education to combat racism and sexism and make an educational contribution to the ending of discrimination on any ground such as sex, race, colour, language, religion, political or other opinion, national or social origin, association with a national minority, property, birth, age, disability or sexual orientation.

5) To help develop good practice and strategies in education which will futher the aims above.

6) To establish and maintain links with projects and networks in Europe and in other countries and to publish a termly bulletin to facilitate this.

The first major project of the Network was to organise the Human Rights Education Forum and Fair to coincide with the 40th anniversary of the Universal Declaration of Human Rights in December 1988. Funding for this was secured from the Joseph Rowntree Charitable Trust, whilst the employment of a professional co-ordinator was supported by the European Human Rights Foundation.

Following this, the Network worked hard to influence the work of the National Curriculum Council during the development of the National Curriculum, and it sponsored a major curriculum development programme.

Aside from this work, the Network held an annual summer conference, produced some books on English, History and Foreign Languages in the curriculum. Summer schools followed in the late 1990s. Money secured from Europe also meant that the Network had to formalise and draw up a constitution.

The Network boasted members such as Hugh Starkey, Margherita Rendel and Audrey Osler. Eventually, after long periods of inactivity, the Network came to an end in 2005.

Sir David Eccles opened the Parent Teachers' Association Fête at Lyneham County Primary School, 15th July 1961.

The General Teaching Council (GTC) (England and Wales) was the culmination of a series of initiatives intended to push for the creation of an English General Teaching Council. There had been previous attempts by CATEC (Campaign for a General Teaching Council) in 1980-1981; the Joint Council of Heads in 1982; and a UCET (Universities Council for the the Education of Teachers) led the initiative from 1983-1990. This last was a grouping of educational and teaching organisations which led to the creation of a GTC working party chaired by John Sayer. The working party held meetings, wrote papers on the role and function of a GTC and put together an outline for a development action plan.

This work was taken forward by the creation of a registered company named GTC (England and Wales), incorporated in August 1988. Its first directors were Mary Russell and John Sayer, and the company lay dormant for a year until it could take over officially from the UCET initiative ( in February 1990). Its aims were to promote' the establishment of a statutory GTC for England and Wales' and '... to liaise with the teaching profession and its representative associations, with statutory and non-statutory educational bodies, and with others representing key public interests'.

The elected executive committee of GTC (England and Wales) comprised 8 Honorary Directors and 1 Honorary Secretary. The Directors were taken from various associations which had been meeting on an informal basis to further the idea of a general council, a grouping which was known as the Forum. John Sayer became the Honorary Secretary. For the next nine years, the Executive Committee met one month before and after each of the termly Forum meetings. Following an initial rotation of the Chair, John Tomlinson was approached to act as a permanent Chairman in 1990. In 1994, Malcom Lee became the Honorary Treasurer, John Sayer became Vice-Chair, and Roger Haslam took over as Secretary. Administration was undertaken on shoe-string budget provided by contributions from Forum associations, and the work was mostly voluntary. Tomlinson, Sayer, Haslam and Lee remained as the main administrators untill 2000. The GTC (England and Wales) was housed in a NATFHE building in Britannia Street, London.

Alongside the GTC (England and Wales), which acted as a political pressure group, the GTC (England and Wales) Trust was created as registered educational charity. This parallel organisation focused on the non-political aspect of the work and served as a vehicle for deliberations on professional matters. Its charitable status allowed it to accept money from funding bodies such us the Paul Hamlym Trust, the NATFHE Educational Trust and the Association of Education Committees Trust.

The GTC (England and Wales) and the associated Trust worked hard to promote legislation for a statutory GTC. It also produced written proposals and responses on teacher induction, initial teacher education and training, and continuing professional development. Links were formed with other teaching councils, especially Scotland, as well as organisations such as CATE (later the TTA), OFSTED, SCAA (now QCA), FEDA, and local authority associations such as WJEC, ACC and AMA.

A General Teaching Council for England was formally agreed in 1998 by the Teaching and Higher Education Act, which also made provision for the establishment of a General Teaching Council for Wales. The GTC for England was finally founded in September 2000 after several years of negotiotions. The GTC ( England and Wales) and GTC ( England and Wales) Trust were dissolved in 2001.

Before Adolf Hitler came to power in Germany, Hilde Jarecki moved to England and was later involved in bringing children safely to Britain via The Kindertransport. She spent around 20 years working as the Senior Professional Advisor for the London Playgroup Association. As part of her involvement, early on she carried play equipment to the new playgroups, gave advice to members, organised meetings and had a major role in the playgroup movement. Hilde was the first person to introduce the concept of mothers helping in the playgroup that their child attended. She is perhaps best known for her book Playgroups: a Practical Approach, which was published by Faber in 1975. The publicity information for this book states: 'Hilde Jarecki, a professional adviser who has spent eight years as an organizer and tutor for the Inner London Playgroups Association, has written an essentially practical handbook based on her extensive experience, which will be invaluable for those employed full time in pre-school playgroup work and for parents of young children.' In the foreword of the book, written by Edna Oakeshott, March 1974, she describes Hilde Jarecki as: 'a pioneer who has given of herself unsparingly to establish a smooth-running organization on a professional footing. No more living recommendation could be provided than her vivid pictures of children and their parents in the playgroup setting.' Hilde continued her pioneering work within the playgroup movement until she was unable to continue on the grounds of ill health.

Born, 1918; educated Christ's Hospital, Horsham; Oxford (chemistry); research chemist, Glaxo, [c1940]-1943; Naval Air arm, [1943-1945]; sub-lieutenant careers advisor, Lee-on-Solent, 1945; school teacher, Devon, [1945-1950]; worked in recruitment, British Nylon Spinners [1950]-1960; Secretary of the Manchester University Careers and Appointments Service, 1960-1984; died 1995.

When, in 1928, the Joint Board scheme for the association between universities and teacher training colleges was adopted, the University of London adopted a scheme under which it took responsibility for syllabuses and examinations in seventeen London training colleges. The scheme was administered by a Training Colleges Delegacy appointed annually by Senate. This was composed of representatives of the Colleges, the London County Council and the University. It was responsible for the approval of syllabuses, the admission of new Colleges to the scheme and the periodic visitation of member institutions. It appointed an Examinations Council and an Advisory Board to carry out specific tasks. The Colleges themselves were divided into groups, each associated with a 'parent' university college, and each with its own Committee. The Domestic Subjects Group was composed of the National Training School of Cookery, later re-named the National Training College of Domestic Subjects, the National Society's Training College of Domestic Subjects (also known as 'Berridge House') and Battersea Polytechnic Domestic Science Training College. The 'parent' college was King's College of Household and Social Science.

From its establishment in 1902 the London Day Training College was governed by a Local Committee appointed by the Technical Education Board (TEB) of the London County Council (LCC). This was originally composed of representatives from the TEB, the Senate of the University of London and the London School Board. From 1904, when the LCC took responsibility for all education in London, the LDTC Local Committee reported to the LCC's Higher Education Sub-Committee and was composed of the Chairman of the LCC, the Chairman and Vice-Chairman of the LCC Education Committee, the Chancellor and Vice-Chancellor of the University of London and six representatives each from the University and the LCC. In Nov 1909 when the LDTC became a School of the University, the composition of its governing body was altered to include the College's Principal and Vice-Principal. At the same date it changed its name from the LDTC Local Committee to the LDTC Council. The LCC retained financial control while the LDTC Council was responsible for all other management issues. In Jun 1930, with a view to the transfer of management of the College to the University of London, Senate appointed a Transfer Committee which reported in Jul 1931. A Provisional Delegacy, appointed by Senate, took over management in 1931 (see IE/ULD). In 1932 full control of the LDTC was transferred to the University of London, not as a School, but as a central activity of the University, and was re-named the Institute of Education. From this date it was governed by a Delegacy appointed by Senate and an Academic Board (see IE/ACB) composed of Institute staff.

When, in 1928, the Joint Board scheme for the association between universities and teacher training colleges was adopted, the University of London adopted a scheme under which it took responsibility for syllabuses and examinations in seventeen London training colleges. The scheme was administered by a Training Colleges Delegacy appointed annually by Senate. This was composed of representatives of the Colleges, the London County Council and the University. It was responsible for the approval of syllabuses, the admission of new Colleges to the scheme and the periodic visitation of member institutions. It appointed an Examinations Council and an Advisory Board to carry out specific tasks. The Colleges themselves were divided into groups, each associated with a 'parent' university college, and each with its own Committee.

The Archive of the Board of Education Inspectors' Association was named after Jack Kitching who was an HMI (Her Majesty's Inspector of Schools) from 1973-1982 and subsequently Honorary Archivist of the Association. Founded in 1919 as a direct consequence of the application of Whitleyism to the Civil Service, the Association was affiliated to the Association of First Division Civil Servants and its executive acted as the staff side of the Inspectorate Whitley Committee. Its main concerns were therefore salaries, pensions and conditions of service, although it also dealt with the function and activities of HMIs. In 1945 it changed its name to the Association of Her Majesty's Inspectors of Schools and in 1973 it amalgamated with the Association of First Division Civil Servants. It wound up its activities in 1992 on the creation of the Office for Standards in Education.

The London Parents Ballot Campaign (LPBC) was set up as a sub-committee of the Parents Central Consultative Committee of the Inner London Education Authority (ILEA), which represented the 3,000 or so elected Parent Governors of ILEA schools. It was run by Thomas Gretton (Chair), Corinne Julius (Secretary) and Diana Simpson (Treasurer), along with scores of volunteers. The Campaign was intended to ask the opinion of parents about the transfer of responsibility for education services from the ILEA to local authorities. The abolition of the ILEA was included in the 1988 Education Reform Bill, but had not been mentioned in any of the consultation documents. The LPBC was an attempt to canvass the views of parents before the Bill passed to the House of Lords. An initial press conference announcing the campaign was held on the 8 February 1988, and the Ballot took place in the last two weeks of March. The Campaign was funded through voluntary contributions from parents, businesses, unions and London boroughs; as well as fundraising events, culminating in a gala performance at the Albery Theatre. The ballot was supervised by the Electoral Reform Society, and provided one vote for each of the 280,000 children in London schools. It closed on the 31st of March, and revealed a 55 per cent return and a 94 per cent vote against the government's ILEA abolition proposals. The ILEA was abolished in March 1990.