The collection consists of approximately 100 items on alchemy and early chemistry, the most notable item being De Secretis Mulierum. The collection also includes manuscripts of lectures given by Sir Henry Roscoe; his notes on solar chemistry work; letters written to him by a number of his peers and his notebook from 1849. The many volumes of letters in the collection includes correspondence with contemporaries such as Robert Bunsen, Michael Faraday, Dmitri Mendeleeff and Louis Pasteur as well as with a number of Presidents of the Chemical Society and the Royal Institute of Chemistry.

Council Attendance Book of Royal Society.

Letters sent to the Royal Society, its President or Officers. Subject matter is both domestic and scientific. Domestic concerns include such matters as instructions from authors on the publication of papers. The letters on scientific topics appear to be those which were considered of small significance, e.g. giving notice of minor inventions, or appealing to the Society for recognition.

Copies of outgoing letters from the President, Officers and Assistant Secretaries. Each page may contain up to four copied documents. Volumes are numbered 1-73 with an additional volume for the period January 1901-November 1904.

Copies of the outgoing letters written by the Foreign Secretaries of the Royal Society.

The manuscript versions of papers published by the Royal Society in the 'Philosophical Transactions'. The series has many points of interest, which include authors' corrections to manuscripts, and the presence of original illustrations in various media (drawings, watercolours and photographs) bound in the volumes. Not all of the material printed in the 'Philosophical Transactions' relating to Society business survives, but manuscript examples of meteorological observations, lists of presents and annual indexing may be found in volumes 8, 9 and 12.
Papers are usually bound into vellum-covered volumes by year of publication, although a few (volumes 4, 5, 8, 9, 12, 17, 73-75) are loose, boxed items. Several gaps appear in the collection, notably for the period 1825-1839 (volumes 18-22) and any year may lack one or more papers; these omissions are noted at the beginning of each part. Despite this, the series constitutes a large, relatively complete run.

A small collection of photostats or photocopies of manuscripts held in other institutions, but of some relevance to the Royal Society and its own Archives. The series largely consists of groups of correspondence, notable letters to Julius Plucker (PH.1) letters of Hevelius, Newton and Flamsteed (PH.2) and of Edmond Halley (PH.3) There are some records of other institutions, including a minute book of the Physiological Society 1876-1892 (PH.9), and copies of Rutherford's correspondence at the Cavendish Laboratory.

A series of (generally) printed material relating to, and commenting on, the Society's activities. The press cuttings and scrap books contain cuttings from newspapers interspersed with other printed matter, and occasionally items of manuscripts. The remaining volumes are concerned with particular events or subjects, such as 'HMS Challenger 1872-1895' or 'National Antarctic Expedition 1899-1904'. There are three types of volumes; the first volume is for the years 1846-1876, but therafter two types of book were kept;

a) biographical - 12 volumes, 1872-1910

b) general, 10 volumes 1885-1910.

These were discontinued for a short period, then merged: 36 volumes, 1918-1976. Thereafter newscuttings were photocopied and kept in monthly bundles.

The Register Books contain copies of scientific papers submitted to the Society - the original documents may be found in the Classified Papers. The papers were transcribed in order to establish their precedence for a particular discovery or idea. Therefore not all communications to the Society were registered in this manner, but only those judged to contain some significant material. Dates as listed are those in which the paper was communicated to the Royal Society; dates of writing, where given, are included in the description of each paper. Many of the these papers were published in 'Philosophical Transactions'.

Letters to Sir Arthur Rucker, his wife and daughter, during the late 19th and early 20th century; many of them from scientists, including J J Thompson, William Huggins, Aston Webb, David Gill, N S Maskelyne, A Geikie. Together with assorted notes and ephemera.

Papers of William Sharpey including copy letters, correspondence including from Neil Arnott, George Gabriel Stokes and James Newton Heale and notes by Sharpey, some on Royal Society business.

The bulk of the collection consists of correspondence: the Singers were clearly vigorous letter writers and both Charles and Dorothea had an enormous number of family, friends and acquaintances. Unfortunately many of their letters were hand written and very few carbon copies survive. Very occasionally an attempt at methodical selection and arrangement is evident: on the whole correspondence had been kept in alphabetical order, and this has been retained in the arrangement of the collection. Dorothea and Charles' correspondence was fairly mixed (reflecting their working life together) with the exception of two distinct groups: correspondence about Dorothea's research on alchemical manuscripts, and later correspondence about her hearing aids.

The main part of the collection centres on the correspondence; this has been grouped together in a self-evident sequence: writings and biographical personal papers follow. Certain of Dorothea's papers remained clearly distinct and these have been kept together. Section E contains a variety of material relating to Jewish refugees, which had been placed on one side by Dorothea after the war for permanent preservation. It has not been listed in detail but sorted into three broad categories. The last section, comprising additional correspondence of the Singers with Sir Zachary Cope, Sir Arthur Salusbury MacNalty and Dr F N L Poynter, is not strictly part of the collection, but these groups of correspondence were given to the Institute to be placed alongside the Singer papers.

Sir Robert Southwell's Lecture on water at the Royal Society, 8 Apr 1675.

Paper for reading before the Royal Society entitled 'Theora Magnetis explicata e sola virium attractivarum universalium natura, elaborata per Franciscum Intze.....Claudiopoli Transylvaniae MDCCCXXV'.

Written in England. Contains the curious characters known as the Boetian contractions, and is a valuable document for the history of arithmetic. The treatise commences on the Roman abacal system, and afterwards proceeds to give an explanation of the Eastern Boetian system with altered characters, and with a complete adoption of the advantages of local position. In Folio 2, recto, line 5, the author says that he will expound 'quaedam de numerorum scientia. regulis uidelicet algorismi' and on Folio 3, verso, he refers to Pithagoras, Nicomachus, Apuleius and Boethius. The text ends on the first line of Folio 34, recto, and is followed by eight lines in a semi-current 13th century hand.

Folio 1, recto ' Prefatio sequentis operis. Vt ait salomon.. punge oculum. et profert lacrimam. punge cor' et profert sensum.....'

Folio 4, verso ' De impari numero..'

Folio 6, verso, line 6, ' Divisio algorismi '. The divisions are given as folows; ' digitus, mediato, multiplicatio, divisio '

Folio 8, recto, title in red in margin, ' Qualiter digitus multiplicat digitum '

Folio 9, recto, line 15 ' Qualiter articulus multiplicatur per articulum '

Folio 9, verso, line 13, heading in red, ' Qualiter digitus multiplicat articulum '

Folio 10, recto, line 10, heading in red, ' Qualiter compositus per compositum multiplicatur '

Folio 10, verso, heading in margin, ' Qualiter compositus multiplicat compositum non eundem habens articulum '

Folio 11, recto, bottom line, heading in red ' Regulo ab uno inequalibus '

Folio 12, recto, line 6, heading in red, ' Regula ab uno in equalibus binario adjecto '

Folio 12, verso, line 8, heading in red ' De duplicatione '

Folio 13, recto, line 5, heading in red, ' De pari adjecto '

Folio 13, verso, line 6, heading in red, ' De impari adjecto '

Folio 14, verso, heading in margin, ' De proposito secundum novenarium dispositum '

Folio 15, recto, line 7-8, heading in red, ' De significationibus et nominibus figarum et locorum '
Transcript extract from line 14 ' Prima itaque omnium est igin. 1. id est unitas. Secunda andras. 2. id est binarius. Tercia ormis. 3. id est ternarius. Quarta arbas. 4. id est quaternarius. Quinta quimas. 5. id est quinarius. Sexta caltis. 6. id est senarius. Septima zemis. 7. id est septenarius. octava celentis. 8. id est octonarius. Nona cemenias. 9. id est novenarius. Singule ataque figure in quocumque loco sint sui ipsius exprimunt significationem. Nunquam enim figura unitatis officium binarii sibi usurpabit, nec binarius ternarii, nec ternarius quaternarii, nec quelibet ceterarum quod alter significare poterit. Ad majorem itaque evidentiam significationes locorum ponamus. primo ita loco posita igin seipsam, id es unitatem, significat. Secundo denarium. Tercio centenarium. Quarto millenarium. Quinto decem milia. Sexto centum milia. Septimo mille milia. Decimo mille mille milia. Undecimo decies milies mille milia. Duodecimo centies milies mille milia. Terciodecimo milies milies mille milia, et sic usque in infinitam singulorum decuplationem locorum extenditur. Similiter autem et andras rimo loco seipsam, id est binarium, significat. Secundo xx. Tercio cc. Quarto duo milia. Quinto xx. Sexto cc. Septima mm. et sic per cetera loca eodem cemate et cetere figure secundum propriam differentiam decuplabutn singulos articulos per loca singula. Est adhucet decima figura cujus nulla significatio est, sed tamen per loca disposita ceterarum significationes auget vel minuit. Dicitur autemzifera, et taliter depingitur 0. Sciendum autem quod omnes figure versus sinistram scribi debent, quia sic vim extendunt. Sed e converso literali ordine legi. '

Folio 17, verso, line 6, heading in red, ' De subtractione'

Folio 18, verso, line 8, heading in red, 'De dupli``catione'.

Letters from various scientists to Walter White, Assistant Secretary of the Royal Society. With occasional material addressed to Charles Richard Weld and others. Usually on Royal Society business.

The archive correspondence can be characterized as the routine treatment of important events. In 1863, for example, Richard Owen wrote to White with brief instructions for his paper describing the feathered dinosaur archaeopteryx. Occasionally the letters are more significant for the Society's history. In an extended note of 1865, ex Royal Society President the Earl of Rosse 'a plain well-grown man, farmer like in appearance' discussed the merits of signing an election certificate for Alfred Lord Tennyson (1809-1892). 'My opinion...was that it would be better to take the broad view and to elect men of great abillity...so as to strengthen the Society in carrying out, in the largest sense, its great object, that of improving natural science'. Tennyson was duly elected, an event which must have pleased White. The assistant secretary had become friendly with the Poet Laureate in the 1850s and White's published diary left a vivid picture of Tennyson reading aloud his Arthurian romances in the offices of the Royal Society.

Papers of Maurice Hugh Frederick Wilkins, 1854-2004, including: laboratory notebooks, graphs, data sets, notes, x-ray diffraction photographs and published articles relating to his scientific research, 1948-1976, chiefly his work on the structure of DNA, 1947-1966; correspondence, 1948-2004, with and about scientific colleagues, including Struther Arnott, Allen Blaurock, Francis Crick, Boris Ephrussi, Harriet Ephrussi-Taylor, Bruce Fraser, Meyer Friedman, Raymond Gosling, Leonard Hamilton, John Kendrew, Robert Langridge, Don Marvin, Linus Pauling, Max Perutz, John Randall, Alec Stokes, James Watson and Herbert Wilson. Correspondence, notes and articles, 1950-2003, relating to research on the history of the discovery of the structure of DNA, including: copies of Rosalind Franklin's laboratory notebooks and articles, 1951-1953, relating to her DNA research; correspondence, 1967-2003, with writers on DNA history, including Aaron Klug, Robert Olby, Meyer Friedman, Horace Judson and Watson Fuller; unpublished articles and talks on DNA history by Wilkins, 1975-1987. Drafts, notes, correspondence and collected background research relating to Wilkins' autobiography, The third man of the double helix (Oxford University Press, 2003). Papers relating to Wilkins' education and early career, 1928-1942, including: teenage essays and fiction on the role of science, 1928-1934; notes, articles and photographs, 1937-1938, relating to his student activities, including physics experiments, and photographs relating to his incendiary bomb testing for Cambridge Scientists Anti-War Group, 1938. Correspondence, memoranda, minutes, reports and notes, 1962-1982, relating to the administration of the Medical Research Council (MRC) Biophysics Unit, King's College London (from 1964, the Department of Biophysics), on topics including funding, staffing, equipment provision and teaching. Correspondence, course handouts, student essays (CLOSED) and background material, 1971-1996, relating to the undergraduate course, 'The social impact of the biosciences', created and run by Wilkins, 1972-1982. Correspondence, newsletters and conference papers relating to Wilkins' involvement in political pressure groups, 1968-2003, notably the British Society for Social Responsibility in Science (of which Wilkins was founding President, 1969-1991), Food and Disarmament International (Wilkins' was founding President, 1984-2004), the Campaign for Nuclear Disarmament (CND), and the Pugwash Conferences on World Affairs. Audio recordings, 1972-1996, including lectures by Wilkins on: social responsibility in science; his Eddington Memorial Lectures,Cambridge, 1977-1978, on the history and philosophy of science; nuclear disarmament, 1981; his retirement speech, 1982; the history of DNA.

Although the collection is by no means comprehensive, there are interesting records of many aspects of Wilson's career.

Section A. Biographical: Brings together material relating to obituaries, tributes, honours and awards. Includes Wilson's account of his First World War experiences and his assessment of his scientific publications. Section B. Research: Although not extensive, provides documentation of a number of Wilson's principal interests including the Salmonella group of bacteria and milk hygiene. There are three laboratory notebooks with experimental data covering the period 1919-45. Section C. Public Health Laboratory Service (PHLS): Relates chiefly to the unpublished history written by Wilson after his retirement as Director of the PHLS. There is also a little material relating to laboratory design and equipment and PHLS personnel. Section D. Lectures and publications: The most substantial in the collection. There are records of Wilson's lectures for a period of forty years from 1944, extensive documentation of the later editions of Principles of bacteriology and immunity, and editorial correspondence and papers for the British Journal of Experimental Pathology and the Journal of Hygiene. Section E. Societies and organisations: Documentation of Wilson's association with ten British organisations including the Medical Research Club, Medical Research Council and Veterinary Club. The Medical Research Council material relates to the Working Party on Tristan da Cunha which was set up to supervise medical investigations when the inhabitants were evacuated to Britain after the island's volcano erupted in 1961. There is also material relating to the Research Foundation, Chicago, which specialised in tuberculosis research, on whose medical advisory committee Wilson served. Section F. Visits and conferences: Records of a number of overseas trips in an advisory capacity for the World Health Organisation, including to Ethiopia 1964, Iraq 1965, Iran, Sudan and Egypt 1971 and the Philippines 1972, and records of international microbiology congresses. Section G. Correspondence: Although not extensive, includes a chronological sequence of scientific correspondence, 1930-1987, Wilson's collection of autograph letters addressed to Topley and himself, and references and recommendations. Section H. Photographs: Photographic records of Wilson, colleagues, conferences and PHLS laboratories. Section J. 'Biographical History of Bacteriology': Manuscript of Wilson's history, with correspondence about publication.

Notes on the history of science.