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Papers of Sir Edward Mellanby, 1896-1974, notably relating to his research interests in vitamins, nutrition and deficiency and material on his activities subsequent to his retirement as an advisor on questions of research and medical administration. May Tweedy married Edward Mellanby in 1914 and collaborated in his research throughout the rest of their lives together, as well as working independently. It can thus be seen that it is not altogether easy to differentiate between the papers of this couple; for example in Section C of Sir Edward's papers are included a number of files and volumes relating to his wife's work as his associate, while her diaries in Section E contain details of her husband's activities as well as her own. Although Lady Mellanby was Sir Edward's collaborator throughout the course of his career, her papers are on the whole distinct from his and concentrate on her work in research into dentition and dental problems. They are therefore listed separately, and the list annotated at relevant points where there is an overlap. It is clear that these papers are not a complete record of the Mellanbys' careers. It is likely that following Sir Edward Mellanby's death, when the material underwent various moves, some items were lost. However, as for 16 years he was Secretary of the Medical Research Council, the record of those years is to be found among the files of the MRC, although details of the relevant files at the MRC are not yet available.