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The collection is divided into four main groups: The first group contains papers relating to William Clift's work as conservator of the Hunterian Museum. This is the largest of the four groups and contains a number of sub divisions such as explanation and display of specimens, expanding the collections, administration of the museum, and correspondence. This group also contains the transcripts made by Clift and others of the Hunterian manuscripts. The second group contains work carried out by William Clift as an illustrator for publications. The third group contains a small amount of personal material that is in the collection. The fourth group contains transcripts and copies of manuscript material by William Clift that is held in other repositories such as the Natural History Museum.

Papers of Sir George Cockburn, relating largely to Napoleon's transportation and imprisonment in St. Helena and there is also a very detailed personal diary, 1797 to 1818. There are no papers for his later career.

Papers, c1914-1989, of Dame Kathleen Lonsdale.

Biographical material includes correspondence and papers relating to imprisonment in Holloway Prison, with Lonsdale's own accounts of her time there; diaries and personal notebooks, 1946-1969; letters of congratulation on election as Fellow of the Royal Society (1945); various photographs dating from school to her later years.

Papers relating to Lonsdale's teaching and administrative work at University College London include papers on teaching undergraduate and postgraduate courses; significant documentation relating to laboratory personnel, research funding and general university administration; papers relating to the 'Round Table on Peace Studies', which proposed the establishment of a centre for research into international conflict at the University.

Research material, 1924-1970, consists of Royal Institution papers comprising notebooks, one dating from Lonsdale's first period there (1923-1927), correspondence with colleagues such as W H Bragg and J M Robertson, and Lonsdale's notes and drafts for various research topics; correspondence and papers from her University College years covering many different areas of research, including diffuse scattering of X-rays, thermal vibrations in crystals, methonium compounds and urinary calculi (the latter topic particularly well documented and including several case studies), and including a large group of photographs, mostly of X-ray diffraction patterns.

Papers on the preparation of volumes of the International Tables for crystal structure determination from Lonsdale's chairmanship of the Commission on Tables (1948) comprise drafts, notes and correspondence with colleagues and publishers.

Extensive papers relating to publications, lectures and broadcasts include drafts of articles, on subjects including peace and religious issues, also including obituaries and biographical articles on various individuals, books, book reviews, obituaries, and letters to newspapers and magazines, the latter principally on the issue of atomic weapons; general correspondence concerning publications; drafts of lectures, 1945-1970, including ethics and the role of science in society; a large series of lecture notes, 1933-1970; scripts for broadcasts, on topics ranging from crystallography to religion, 1945-1967.

Papers on foreign and domestic travel, 1943-1971, relating to conferences and lectures, on crystallography, science ethics, and work for the Society of Friends, including her visit to China (1955) and her world tour (1965).

Papers relating to organisations, notably the British Association for the Advancement of Science (BAAS) and the International Union of Crystallography (IUCr), including material relating to a number of International Congresses of Crystallography, also papers relating to participation in Pugwash Conferences on World Affairs, 1958-1970, and papers concerning prison reform and the running of Bullwood Hall Borstal, Essex.

Correspondence, 1927-1974, comprises two main sequences, one arranged alphabetically, the other chronologically; 'day files', principally carbons of outgoing correspondence, 1966-1969; a sequence of references and recommendations; also including correspondence relating to Lonsdale's period of imprisonment (1943). Correspondents include scientists such as Max Born, W H Bragg, W L Bragg, E G Cox, Dorothy Hodgkin, Judith Milledge, L C Pauling and A J C Wilson.