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The Brain archive comprises his personal and professional papers together with sampled case notes from his private practice, 1865-1977. As well as medical papers, there is a significant amount of material relating to Brain's philosophical and literary interests, and some papers of Brain's family and of his wife Stella (nee Langdon-Down).

Miscellaneous papers of George Colebrook including lectures and treatises on diseases, 1678-1716.

Josiah Colebrook: Commonplace book of prescriptions for diseases, [1700].

Minute book of the Society of Collegiate Physicians, 1767-1798.

Case records, Chester General Infirmary, 1769.

Author's manuscript of 'Observationes medicamentorum' comprising short comments on various passages of Paulus Aegineta.

Letters and papers relating to the 'madness' of King George III, 1788-1886.

Medical and pharmacological notes probably in hand of Timothy Goodwin, [1690].

Correspondence and papers of William Alexander Greenhill, 1839-1894, mainly relating to medical biography including notes on Galen; notes on the classification of animals; printed drawings of surgical instruments; notes on Arabic medicine and transcripts of Arabic texts; five engravings of Halle and engraving of A H Francke's Monument; prescriptions; biographical notes on doctors and other eminent men and correspondence, chiefly on his work on Galen.

Notebooks of William Harrison containing notes on the practice of physic, pharmacy, midwifery, varia and botany, materia medica, toxicology and chemistry, [1852].

Recipe books of Philadelphia Lee, [1780].

Memoirs of Richard Pulteney by his friend William George Maton, MD, prefixed to a second edition of Dr Pulteney's Life and writings of Linnaens, (1805), illustrated by various original letters, drawings, prints etc. and interleaved with diplomas from various medical societies, and catalogue of the library of Dr Pulteney.

Samuel Merriman's annotated copy of A Synopsis of the various kinds of difficult parturition, 1814.

Personal papers of Alan Nabarro and his family, particularly those papers relating to Alan's experiences of living with diabetes and his diabetes-related work, as well as literature and ephemera collected by Alan and his family on the subject of diabetes.

English translation by N Peters in 1739 of Richard Lower's Tractatus de corde (1699), with finely drawn copies of the seven plates at the end.

Joseph Phelan: lists of names of medicines in Indian languages, late 18th century.

Copy of Thomas Sydenham's 'Processus integri', interleaved, with notes on medicine in the handwriting of Sir John Pringle.

Correspondence and papers of Sir Benjamin Ward Richardson, 1846-1897, including notes taken by Richardson as a medical student from the lectures of Dr J A Easton, Professor of Materia Medica, Andersonian University, Glasgow, Winter Session 1846-1847; papers relating to Richardson's life of Thomas Sopwith, the mining engineer, comprising Sopwith's original diaries, or a transcript of them, with Richardson's explanatory notes inserted; papers and drafts of Richardson's unfinished autobiography published posthumously under the title 'Vita Medica'; lecture notes on human physiology; Richardson's case book, 1852-1861 and unpublished works by Richardson.

Correspondence relating to the Royal College of Physicians Fellows' and members' business and partnership interests, 1911-1949.

Papers and notes of Alexander Patrick Stewert on typhus and typhoid, 1838-1844.

Papers of John Stephen Taylor including daybooks with notes of patients and prescriptions, 1940-1952; diaries, 1946-1965; Men in the wilderness, an unpublished novel on medical life; book of examinations and reports made for the Prudential Insurance Company, 1894-1947; Taylor's visiting books, 1940-1947; ledgers relating to Taylor's practice at Thorne, 1888-1952 and cash books, 1917-1957.

Papers of Shepherd Thomas Taylor including medical diary, general diaries, notebook with notes of lectures on internal cancers, accounts, 1859-1925.

Record of post-mortem examinations by James Wilson and James Arthur Wilson including the post mortem examinations of the bodies of Dr Samuel Johnson and Lt Gen Sir Charles Napier, 1784-1853.

Letters relating to illness and death of Charles James Fox and other members of the Fox Family, 1806-1819.

Widdows Golding collection comprising a commonplace book containing records of cases at the London Hospital about the year 1786, including notes on operations performed by Richard Grindall, Henry Thompson, George Neale, and other surgeons; notes on surgery, midwifery and anatomy. (The anatomical notes are illustrated by fine water-colour drawings). 'A concise account of an epidemic fever which was in the united parishes of Newnam, Mongwell, Nufhill and Gray's in the year 1788' and notes on medicine. At the end is a large collection of receipts.

Joannes Groenevelt's copy of his book, 'Dissertatio lithologica variis observationibus et Figuris illustrata', 1687, interleaved with manuscript notes.

Papers of Reginald Hale-White chiefly relating to the Fellowship for Freedom in Medicine, including correspondence; address at the Tunbridge Wells meeting of the Fellowship for Freedom in Medicine, Apr 1953; typescript drafts of reports; press-releases and printed Bulletins of the Fellowship for Freedom in Medicine, 1948-1972 (some were added to the collection by Hale-White's widow after his death). Also comprises material about his other medical interests including correspondence and other papers about the Government proposal to ban the manufacture and import of heroin in the United Kingdom, and about Hale-White's participation in opposing the ban, 1955-1956; copies of letters from Hale-White to the Daily Telegraph and the British Medical Journal, 1958-1967 and typescripts of speeches and lectures given by Hale-White, some annotated by him in manuscript.

Unpublished memorandum by Sir Frederick Norton Kay Menzies on the London County Council hospital service, 1941.

John Ayrton Paris' annotated copy of 'A memoir on the physiology of the egg', read before the Linnean Society of London, 21 Mar 1809' (London 1810), with two unpublished watercolour drawings by M C Noble interleaved.

Association of Physicians of Great Britain and Ireland records comprising: attendance records 1907-1960, cash book 1907-1967, correspondence 1925- 1970, minutes 1907-1970, and photographs 1907-1949, of the Association of Physicians of Great Britain and Ireland.

Papers of Frederic John Poynton, [1902]-1940, including scrapbook, with letters and newspaper cuttings relating to Poynton and addresses including on the occasion of the unveiling of a memorial to Dr William Oliver, on the history of early aeronautics and the history of the Hospital for Sick Children, Great Ormond Street.

Original manuscript of Manual of Morbid Anatomy by Humphry Davy Rolleston and Alfredo Antunes Kanthack, 1894.

Case notes compiled at Westminster Infirmary, containing the records of 169 patients at the Westminster Hospital. 94 patients were seen by Dr Wasey and 75 by Dr Stuart. There is an index of patients at the front, and an index of diseases at the back.

Original drawings of natural history and comparative anatomy for Edward Tyson's works on comparative anatomy.

A Greek and Latin etymology of medical terms, 1722-1724.

Minutes of general meetings of governors of the Westminster General Dispensary, instituted 6 June 1774.

Casebook of Isaac Burney Yeo, 1871-1880.

Three volumes, 1830, of translated 'Elements of practical medicine elucidated by cases' by Ignaz Rudolph Bischoff.

Volume of pharmacopocia by Thomas Crane entitled 'Pharmacopocia Dr. Caroli Scarborough Esq. Aurat. Med. Reg. primarii, a reverendo Authoris Filio Carolo Rectore de Upway Comunicata', [1739].

Case books 1877, and post-mortem reports, Deptford Hospital, 1890-1892.

Minutes and accounts of the Drury Lane Dispensary, 1782-1952.

'Some requirements for modern clinical teaching', 1913.

Recipe book, with account of monies recieved, [1720].

Minute book of the Gloucestershire Medical Society, including papers submitted by Edward Jenner and others, 1788-1793.

Case book, with account of last illness and post mortem of King James I, attributed to Thomas Marwood, c 1625.

Letters and papers of John William Ogle including correspondence with Florence Nightingale; other correspondence; articles and booklets by Ogle including on preventative medicine and medical reform; remarks read before a Sub-Committee, appointed to consider the question of Provident Dispensaries, 1857 and plan setting out Ogle's method of record keeping during Cholera epidemic in London, 1854.

Collection of papers by and about Baldwin Hamey (1600-1676); and a biographical memoir of Hamey, 1733.

'A book of Surgerie and Phisick of Mistress Honorie Henslow', by Andrewe Plowden, Servant to Mistress Honore Henslow, 1601.

Notes from the lectures of George Fordyce at his house in Essex Street, Strand, for a period extending over 30 years on subjects including clinical lectures, acute diseases, chemistry, chronic diseases, diseases of women and children, materia medica and the natural history of the human body. Transcribed, mainly from short-hand notes, by Henry Rumsey, one of his pupils, 1785-1787.

Epitome Praxis medicinae by Edward Strother, possibly lecture notes for Praelectiones Pharmaco-logicarum et Medico-practicarum of which he published a syllabus in 1724.