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The papers consist of notes and notebooks of William Bayliss' experiments. There is also correspondence, press cuttings and photographs, a great part referring to the 'Brown Dog Affair' of 1903 and to other disputes between anti-vivisectionists and University College London.

Papers of Sir Ambrose Fleming, including extensive sets of laboratory notebooks which include accounts of experiments on carbon filaments carried out by Fleming when he was adviser to the Edison and Swan Electric Light Company, of tests on electrical and photometric standards carried out in the Pender Laboratory at University College London, and of experiments on valves and other aspects of wireless telegraphy; notes of lectures attended by Fleming and notes for lectures given by Fleming; patent specifications and papers on litigation over them; newspaper cuttings and other compilations by Fleming; papers on awards and distinctions; biographical notes; and correspondence. 500 of the 521 volumes are printed works associated with the collection.

Two lists of specimens, instruments, utensils, drawings, etc, illustrative of comparative anatomy and zoology. Both dated 12 January 1850.

Manuscript record of experiments labelled 'Laboratory Notes', kept while studying engineering at University College London.

Manuscript catalogue of the apparatus used in teaching the natural philosophy class in the Marischal College, Aberdeen.

Papers, 1840-1972, of and relating to Karl Pearson, comprising personal and family papers, 1844-1937 (Ref: 1-45); lectures and lecture notes, 1874-1972 (Ref: 46-84); papers relating to literary and scientific work [1870]-1936 (Ref: 85-229); papers relating to the history of the Department of Applied Statistics, University College London, 1895-1936 (Ref: 230-258); papers relating to the work of the Department of Statistics and of Pearson's colleagues, 1895-1962 (Ref: 267-346); papers relating to the journal Biometrika, 1900-1954 (Ref: 347-570); papers relating to Pearson's The life, letters and labours of Francis Galton, 1840-1931 (Ref: 571-598); papers relating to Pearson's wartime research (1914-1918), 1905-1923 (Ref: 599-612); acquired papers, 1842-1923 (Ref: 613-623); general correspondence [1843-1972] (Ref: 624-933). The collection also includes papers of Walter Frank Raphael Weldon (Jodrell Professor of Zoology and Comparative Anatomy at University College London), 1860-1935 (Ref: 259-266).

Papers, 1922-1980, of Joseph Henry Woodger, consisting of research and personal notebooks, research files, manuscript and typescript drafts of works, correspondence, photographs and printed material.