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The papers are very extensive though there are some lacunae, probably attributable to Chain's many changes of workplace. The early biographical period is sparsely documented, there are sporadic gaps in the correspondence files, and there is no original documentation of the penicillin research at Oxford (although there are many historical accounts and much correspondence about the history of penicillin). The surviving biographical material provides documentation of the arrangements for Chain to live and work in Britain, later honours and awards and his musical interests, and family correspondence, photographs and press-cuttings. There are very substantial records of his later career at the Istituto Superiore di Sanità and Imperial College, London, including his continuing contributions to biochemical problems such as carbohydrate metabolism, ergot alkaloids, edible proteins and aeration studies. The Imperial College material also contains records of the creation, administration, finance and architectural design of the Biochemistry Department, and developments in the Department after Chain's statutory retirement in 1973. Additional information about Chain's research is available in the documentation of his very extensive consultancy agreements and collaborative work with industrial firms such as Astra, Beechams and Rank Hovis McDougall, and records relating to government, grant-giving and charitable bodies such as the British Heart Foundation, Cancer Research Campaign and Medical Research Council which contributed to the funding of his research. There is much material on Chain's lectures, addresses and broadcasts, and on his extensive travel on visits and conferences, which includes a substantial number of unpublished talks.

An exceptional feature of the Chain papers is the documentation of the large number of Israel and Jewish organisations with which he was associated, especially the Weizmann Institute of Science, where he was a governor for many years and had at one time considered taking up an appointment.

The collection provides good documentation of many aspects of McIlwain's career and his contribution to the development of neurochemistry in the UK and internationally.

Section A, Biographical, brings together obituaries, curricula vitae and bibliographies, and material relating to the various stages of McIlwain's scientific career, especially in the 1930s and 1940s, his appointment to the Biochemistry Chair at the Institute of Psychiatry in 1954 and the symposium held in his honour on his retirement in 1980. The section also presents a significant body of material relating to McIlwain's undergraduate studies at King's College, University of Durham, including essays and notebooks.

Section B, Institute of Psychiatry, is principally papers relating to the activities of McIlwain's own Department of Biochemistry and especially its teaching programme in neurochemistry. There is also material relating to various government and University of London enquiries into medical education.

Section C, Research, includes copies of McIlwain's M.Sc. and Ph.D. theses, notes, drafts and reports for early work in the 1930s and correspondence 'from the Lab' for the 1930s and 1940s.

Section D, Publications, lectures and broadcast, is the largest in the collection. It presents significant documentation, especially correspondence, relating to his textbook Biochemistry and the central nervous system which went through five editions, 1955-1985, and important editorial correspondence for the Biochemical Journal (member of the Editorial Board, 1946-1950), Biochemical Pharmacology and Journal of Neurochemistry. There are also drafts for lectures and seminars for scientific audiences in the UK and abroad, principally from the 1960s onwards.

Section E, Societies and organisations, documents McIlwain's involvement with a number of UK and international bodies including the Biochemical Society, the International Brain Research Organisation and the International Society for Neurochemistry (ISN) of which he was a founder member and from 1984 'Historian' of the Society with responsibility for its archives.

Section F, Visits and conferences, covers the period 1947-1993 and is of particular interest for its documentation of the historical sessions which McIlwain organised at ISN meetings.

Section G, Correspondence, presents an alphabetical sequence of McIlwain's correspondence including significant exchanges with a number of distinguished mentors and contemporaries such as G.R. Clemo, F. Dickens, K.A.C. Elliott, P.G. Fildes, S.S. Kety, H.A. Krebs, Derek Richter and F.L. Rose, and a chronological sequence of shorter scientific correspondence covering the period 1938-1992.

There is also an index of correspondents.

Papers of the Medical Research Club, 1891-1974, comprising minute books, 1891-1974; proposal books, 1891-1924; attendance books, 1891-1984; and centenary history, 1992.

Papers of the National Birthday Trust Fund (NBTF), 1928-1993, comprising minutes; committee papers; records of annual general meetings; accounts; administration including maintenance of the building; correspondence relating to members, other organisations and individuals; fundraising and publicity; records relating to analgesia; records of research projects funded by the NBTF; reports to outside bodies; surveys; records relating to the Perinatal Mortality Survey, 1958; records relating to the British Births Survey, 1970; press cuttings; miscellaneous papers; administrative records of the Joint Council On Midwifery; records relating to the Abortion Survey conducted by the Joint Council On Midwifery; records relating to the Nutrition Survey conducted by the Joint Council On Midwifery; personal papers of Juliet, Lady Rhys-Williams DBE (1898-1964), founder member and Chairman for a period until her death; and records relating to non-NBTF organisations.

Papers of the Strangeways Research Laboratory, c 1901-1988, comprising papers of T S P Strangeways; annual reports including 1929-1950; minutes and correspondence of the Trustees, 1929-1971; account books and ledgers, 1929-1970; papers relating to funding from various bodies, 1929-1975; papers relating to Medical Research Council funding, c.1962-1969; papers relating to grants, c.1963-1970 and c.1967-1980; administrative records, 1931-1971; general correspondence, 1942-1947, 1954-1956, and 1965-1970; assorted files, 1930s-1960s; miscellaneous historical material including research by George Eric Howard Foxon; minutes of the Radium Commission, 1932-1943; and papers relating to C F Robinow, E M Brieger and Michael Abercrombie.

Papers of the Wellcome Chemical Research Laboratories, 1899-[1946], comprising correspondence files, a rule book, microfilms of files, and publications.

Papers of the Neonatal Society, 1959-2005, comprising correspondence and material relating to society meetings, membership and constitution.

Papers of the Society for Social Medicine, 1956-2005, comprising administrative records, 1956-2003; minutes of annual general meetings, the executive committee, and scientific meetings, 1957-2005; external relations materials, 1956-2003; mailings to members, 1987-2003; evidence and opinions submitted by the Society; and papers relating to the Society's links with associated organisations.

Papers of the Wellcome Physiological Research Laboratories (WPRL), 1903-1927, comprising publications including handbooks of early information and volumes of staff reprints, and a microfilm copy of a file relating to the history of the Laboratories.

The collection comprises drawings and photographs concerning mosquitos and malaria, plus correspondence with Sir Rickard Christophers.

Minute books of the Council and Executive Committee of the Association for the Advancement of Medicine by Research, with inserted loose papers, from its formation in 1882 until 1892; minutes of the sub-committee on the Promotion of Research, 1882-1883, and letters to Stephen Paget, 1891-1892.

Papers of Egon Kodicek, 1934-1984; comprising biographical and bibliographical items; laboratory notebooks of work at the Dunn Nutritional Laboratory, Cambridge, 1950s-1960s, and writings on nutrition research; some correspondence and photographs.

The collection centres on Wallich's work on biology, particularly marine biology, and his belief that other figures in the field were ignoring or plagiarising his discoveries. As well as his notes, it includes a collection of offprints by Wallich (MS.4969) and a collection of offprints by other scientists, with Wallich's comments (MS.4970).

Although the collection is by no means comprehensive, there are interesting records of many aspects of Wilson's career.

Section A. Biographical: Brings together material relating to obituaries, tributes, honours and awards. Includes Wilson's account of his First World War experiences and his assessment of his scientific publications. Section B. Research: Although not extensive, provides documentation of a number of Wilson's principal interests including the Salmonella group of bacteria and milk hygiene. There are three laboratory notebooks with experimental data covering the period 1919-45. Section C. Public Health Laboratory Service (PHLS): Relates chiefly to the unpublished history written by Wilson after his retirement as Director of the PHLS. There is also a little material relating to laboratory design and equipment and PHLS personnel. Section D. Lectures and publications: The most substantial in the collection. There are records of Wilson's lectures for a period of forty years from 1944, extensive documentation of the later editions of Principles of bacteriology and immunity, and editorial correspondence and papers for the British Journal of Experimental Pathology and the Journal of Hygiene. Section E. Societies and organisations: Documentation of Wilson's association with ten British organisations including the Medical Research Club, Medical Research Council and Veterinary Club. The Medical Research Council material relates to the Working Party on Tristan da Cunha which was set up to supervise medical investigations when the inhabitants were evacuated to Britain after the island's volcano erupted in 1961. There is also material relating to the Research Foundation, Chicago, which specialised in tuberculosis research, on whose medical advisory committee Wilson served. Section F. Visits and conferences: Records of a number of overseas trips in an advisory capacity for the World Health Organisation, including to Ethiopia 1964, Iraq 1965, Iran, Sudan and Egypt 1971 and the Philippines 1972, and records of international microbiology congresses. Section G. Correspondence: Although not extensive, includes a chronological sequence of scientific correspondence, 1930-1987, Wilson's collection of autograph letters addressed to Topley and himself, and references and recommendations. Section H. Photographs: Photographic records of Wilson, colleagues, conferences and PHLS laboratories. Section J. 'Biographical History of Bacteriology': Manuscript of Wilson's history, with correspondence about publication.

Papers of the Lister Institute of Preventive Medicine (LIPM), 1886-1986, comprising minutes, 1886-1982; annual reports, 1895-1986; records relating to the origins and establishment of LIPM, 1889-1898; records of LIPMs links and amalgamations with other bodies, 1886-1898; records relating to vivisection, 1889-1899; Lord Lister's correspondence, 1893-1912; J L Pattison's correspondence, 1898-1903 and 1914; records relating to LIPMs organisation and administration, 1896-1949; production and distribution records for serum and vaccine lymph, 1894-1950; records relating to research projects, 1891-c1940s; records relating to LIPMs relations with outside bodies and individuals, 1889-1975; records relating to properties of LIPM; historical material; biographical material; miscellaneous papers; pamphlets relating to LIPM and associated bodies; pamphlets relating to other institutions; photographs; photocopies of letters from Lord Lister to Dr G Dean; and an index of correspondents.

Papers of the Research Defence Society, 1811-1992, comprising papers; administrative records; correspondence; minutes; records of membership, meetings and rules; annual reports; treasurers reports; accounts; RDS publications including Conquest magazine (which was called The Fight Against Disease until 1950); copies of Acts of Parliament, Bills and Royal Commissions, 1786-1915; correspondence and papers relating to animal rights Bills, 1927-1937 and 1965-1980; literature and publications used by the RDS; anti-vivisection literature; newspaper cuttings; tape recordings and films; and photographs and slides.

Papers of the Wellcome Tropical Research Laboratories, 1899-1943, including the Laboratories' annual reports and reports of the Entomological and Chemical Sections.

Papers of the Wellcome Bureau of Scientific Research (WBSR), 1913-1939, comprising reports, administrative records, correspondence and publications. Including papers relating to the Wellcome Chemical Research Laboratories (WCRL), Wellcome Physiological Research Laboratories (WPRL), Wellcome Museum of Tropical Medicine and Hygiene, Wellcome Entomological Field Laboratories (WEFL), and Burrough's Wellcome and Co. Also containing papers of Andrew Balfour and papers of Charles Morley Wenyon.