Showing 3 results

The papers are very extensive though there are some lacunae, probably attributable to Chain's many changes of workplace. The early biographical period is sparsely documented, there are sporadic gaps in the correspondence files, and there is no original documentation of the penicillin research at Oxford (although there are many historical accounts and much correspondence about the history of penicillin). The surviving biographical material provides documentation of the arrangements for Chain to live and work in Britain, later honours and awards and his musical interests, and family correspondence, photographs and press-cuttings. There are very substantial records of his later career at the Istituto Superiore di Sanità and Imperial College, London, including his continuing contributions to biochemical problems such as carbohydrate metabolism, ergot alkaloids, edible proteins and aeration studies. The Imperial College material also contains records of the creation, administration, finance and architectural design of the Biochemistry Department, and developments in the Department after Chain's statutory retirement in 1973. Additional information about Chain's research is available in the documentation of his very extensive consultancy agreements and collaborative work with industrial firms such as Astra, Beechams and Rank Hovis McDougall, and records relating to government, grant-giving and charitable bodies such as the British Heart Foundation, Cancer Research Campaign and Medical Research Council which contributed to the funding of his research. There is much material on Chain's lectures, addresses and broadcasts, and on his extensive travel on visits and conferences, which includes a substantial number of unpublished talks.

An exceptional feature of the Chain papers is the documentation of the large number of Israel and Jewish organisations with which he was associated, especially the Weizmann Institute of Science, where he was a governor for many years and had at one time considered taking up an appointment.

MSS.3259-3285 comprise chiefly scientific material; they include student notebooks on zoology, botany and geology (MSS.3259-3280); scientific logs from the British Antarctic Expedition (MSS.3281-3283), specifically a biological log (MSS.3281-3282) and a log of whales sighted (MS.3283), both spanning 1910-1913; an address delivered in 1913 to the New Zealand branch of the British Medical Association on Mendel's principle of heredity (MS.3284); and some notes on fish and fishing (MS.3285). MSS.5252-5254 comprise more personal and more miscellaneous material. MS.5252 is a scrapbook kept by Lillie, containing news cuttings, photographs and miscellaneous papers, spanning the period c.1845-1910 and including cuttings (with portrait prints) on science and scientists, 1845-1901; caricatures by Lillie of lecturers and staff at Birmingham University, 1904-1905; geological photographs, 1907-1909; family photographs (including a group class portrait at United Services' College, Westward Ho!, c.1892); and ephemera from Cambridge, 1909-1910. MS.5253 comprises cuttings from newspapers and illustrated magazines, spanning 1910-1914 and mainly relating to Robert Falcon Scott's British Antarctic Expedition. Finally MS.5254 comprises correspondence and very miscellaneous papers from the period 1824-1938 (plus some undated material) among them letters to his grandfather John Lillie D.D. (1806-1866), and to his maternal relatives the Macaire family, and letters to Lillie from E.A.N. Arber, Caroline Oates and others.

Sharpey-Schafer's correspondence is extensive. In addition to his own correspondence it includes papers of William Sharpey, saved by Sharpey-Schafer after his death, 1836-70 and n.d. There are significant numbers of letters from William Sharpey himself, Sir Michael Foster, Sir John Burdon-Sanderson, Sir William Osler, George John Romanes, Sir Victor Horsley, Sir James Paget, Lord Lister, Sir Charles Sherrington, Sir William Gowers, Thomas Henry Huxley, John Newport Langley, Sir Edwin Ray Lankester, Ernest Henry Starling, Allen Thomson, Sanger Monroe Brown, Sutherland Simpson, Francis Gano Benedict, Harvey Cushing, Albrecht Kossel, Karl Hugo Kronecker, Carl Ludwig, Charles Robert Richet, and Masaharu Kohima.

Material relating to Sharpey-Schafer's career at UCL includes correspondence on his controversy in the Neurological Society with Sir David Ferrier, 1887-88, and papers relating to the rebuilding of University College Hospital in 1895.

Material relating to Sharpey-Schafer's career at Edinburgh University includes correspondence on the forced resignation of William Cramer from the department of Physiology on grounds of German nationality, 1914, and papers on the opening of the department of Animal Genetics in 1930.

Other papers reflect various aspects of Sharpey-Schafer's scientific interests, including the history of the Physiological Society (with several letters from Archibald Vivian Hill), artificial respiration and bird migration. There are also numerous letters in response to his controversial address to the British Association in Dundee in 1912, and correspondence on the position of scientists in post-Revolutionary Russia, 1918-21.

There is a substantial correspondence on the various textbooks Sharpey-Schafer wrote or to which he contributed, 1910-34.

Sharpey-Schafer's personal papers include correspondence with his wives and children, 1876-1935, scrapbooks of press cuttings, c. 1899-1930, and a large collection of photographs, mainly portraits.