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The papers are very extensive though there are some lacunae, probably attributable to Chain's many changes of workplace. The early biographical period is sparsely documented, there are sporadic gaps in the correspondence files, and there is no original documentation of the penicillin research at Oxford (although there are many historical accounts and much correspondence about the history of penicillin). The surviving biographical material provides documentation of the arrangements for Chain to live and work in Britain, later honours and awards and his musical interests, and family correspondence, photographs and press-cuttings. There are very substantial records of his later career at the Istituto Superiore di Sanità and Imperial College, London, including his continuing contributions to biochemical problems such as carbohydrate metabolism, ergot alkaloids, edible proteins and aeration studies. The Imperial College material also contains records of the creation, administration, finance and architectural design of the Biochemistry Department, and developments in the Department after Chain's statutory retirement in 1973. Additional information about Chain's research is available in the documentation of his very extensive consultancy agreements and collaborative work with industrial firms such as Astra, Beechams and Rank Hovis McDougall, and records relating to government, grant-giving and charitable bodies such as the British Heart Foundation, Cancer Research Campaign and Medical Research Council which contributed to the funding of his research. There is much material on Chain's lectures, addresses and broadcasts, and on his extensive travel on visits and conferences, which includes a substantial number of unpublished talks.

An exceptional feature of the Chain papers is the documentation of the large number of Israel and Jewish organisations with which he was associated, especially the Weizmann Institute of Science, where he was a governor for many years and had at one time considered taking up an appointment.

The collection provides good documentation of many aspects of McIlwain's career and his contribution to the development of neurochemistry in the UK and internationally.

Section A, Biographical, brings together obituaries, curricula vitae and bibliographies, and material relating to the various stages of McIlwain's scientific career, especially in the 1930s and 1940s, his appointment to the Biochemistry Chair at the Institute of Psychiatry in 1954 and the symposium held in his honour on his retirement in 1980. The section also presents a significant body of material relating to McIlwain's undergraduate studies at King's College, University of Durham, including essays and notebooks.

Section B, Institute of Psychiatry, is principally papers relating to the activities of McIlwain's own Department of Biochemistry and especially its teaching programme in neurochemistry. There is also material relating to various government and University of London enquiries into medical education.

Section C, Research, includes copies of McIlwain's M.Sc. and Ph.D. theses, notes, drafts and reports for early work in the 1930s and correspondence 'from the Lab' for the 1930s and 1940s.

Section D, Publications, lectures and broadcast, is the largest in the collection. It presents significant documentation, especially correspondence, relating to his textbook Biochemistry and the central nervous system which went through five editions, 1955-1985, and important editorial correspondence for the Biochemical Journal (member of the Editorial Board, 1946-1950), Biochemical Pharmacology and Journal of Neurochemistry. There are also drafts for lectures and seminars for scientific audiences in the UK and abroad, principally from the 1960s onwards.

Section E, Societies and organisations, documents McIlwain's involvement with a number of UK and international bodies including the Biochemical Society, the International Brain Research Organisation and the International Society for Neurochemistry (ISN) of which he was a founder member and from 1984 'Historian' of the Society with responsibility for its archives.

Section F, Visits and conferences, covers the period 1947-1993 and is of particular interest for its documentation of the historical sessions which McIlwain organised at ISN meetings.

Section G, Correspondence, presents an alphabetical sequence of McIlwain's correspondence including significant exchanges with a number of distinguished mentors and contemporaries such as G.R. Clemo, F. Dickens, K.A.C. Elliott, P.G. Fildes, S.S. Kety, H.A. Krebs, Derek Richter and F.L. Rose, and a chronological sequence of shorter scientific correspondence covering the period 1938-1992.

There is also an index of correspondents.

Biographical material includes the draft of Mourant's autobiography, Blood and Stones published after his death in 1995, together with the correspondence and papers Mourant assembled while writing it. There is also documentation of Mourant's education at Victoria College Jersey and at Exeter College Oxford. The latter includes notes on lectures 1922 - ca 1926. Documentation of Mourant's career, honours and awards is patchy, although there is material relating to his search for employment in the early 1930s. There are pocket diaries spanning 1915-1982, with a fairly continuous sequence 1922-1961. Biographical material also includes extensive family and personal correspondence, much of which dates from or relates to the German occupation of Jersey or shortly thereafter. Mourant's other documented interests include his membership of the Methodist Church and his political affiliations, the League of Nations Union in particular.

There is a little material relating to Mourant's early career with the Geological Survey 1929-1931, miscellaneous material relating to Mourant's service with the MRC's Blood Group Reference Laboratory at the Lister Institute and the Nuffield (later Anthropological) Blood Group Centre at the Royal Anthropological Institute, London, and more extensive but uneven coverage of the Serological Population Genetics Laboratory. Although there is some documentation of the foundation of the Laboratory 1964-1965 and of its staff, the surviving material consists chiefly of correspondence and papers relating to Mourant's largely successful efforts to find continued funding for the Laboratory 1969-1977. Haematological research material, though not extensive, covers Mourant's work in a number of areas from research on blood serum in the mid-1940s to the mapping of blood groups in the 1960s and 1970s. There are early research notes, correspondence and papers relating to student and other expeditions undertaking blood group and physical anthropology research and some MRC material assembled by Mourant relating to projects in which he had an interest. The largest group of research papers, however, is maps and data produced during preparation of the second edition of The Distribution of the Human Blood Groups. There is a chronological sequence of drafts and correspondence relating to Mourant's publications, 1929-1991, with extensive material relating to editions of The Distribution of the Human Blood Groups and to The Genetics of the Jews (1978). There is also editorial correspondence relating to publishers and journals, chiefly invitations to review books or referee papers and an incomplete set of offprints. There is correspondence and papers relating to some of Mourant's lectures and broadcasts, most notably the lectures on blood groups given at the Collège de France, Toulouse, 1978-1979. Societies and organisations material is not extensive, and is confined to brief documentation of only a few of the societies and organisations with which Mourant was associated. It includes professional and geological bodies as well as haematological, biological and medical organisations. Visits and conferences material covers the period 1960-1987. It is not comprehensive, though there is also considerable documentation of Mourant's visits and conferences in the papers he assembled in the course of preparing his biography and with lectures material. Mourant's correspondence is extensive. Its complexity reflects Mourant's organisation of the material, the bulk of which was found in three main series: 'Foreign 1965-1977', 'Biological' and 'Geological', together with a fragment of a fourth series 'Home 1965-1977'. Principal correspondents include C.C. Blackwell, B. Bonné, O.J. Brendemoen, V.A. Clarke, L.L. Cavalli-Sforza, A. W. Eriksson, T.J. Greenwalt, J.K. Moor-Jankowski, T. Jenkins, W.S. Pollitzer, D.F. Roberts, J. Ruffié, D. Tills and J.S. Weiner.

Sargant was an outspoken supporter and practitioner of what he termed the 'practical rather than philosophical approaches' to the treatment of mental illness, pioneering and publicising various physical treatments and vociferously opposing the use of psychoanalytic techniques. The majority of the collection consists of his writings, both published and unpublished, supplemented by a small quantity of correspondence and other material. In addition, the collection contains clinical records for about 500 cases from Sutton Emergency Hospital in the 1940s. As well as covering clinical subjects (in Sections D, E, and F) and Sargant's views on the practice of psychiatry in general (Section B), the collection also contains material relating to his interest in the related issues of religious conversion and brainwashing (Section G).