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The papers are very extensive though there are some lacunae, probably attributable to Chain's many changes of workplace. The early biographical period is sparsely documented, there are sporadic gaps in the correspondence files, and there is no original documentation of the penicillin research at Oxford (although there are many historical accounts and much correspondence about the history of penicillin). The surviving biographical material provides documentation of the arrangements for Chain to live and work in Britain, later honours and awards and his musical interests, and family correspondence, photographs and press-cuttings. There are very substantial records of his later career at the Istituto Superiore di Sanità and Imperial College, London, including his continuing contributions to biochemical problems such as carbohydrate metabolism, ergot alkaloids, edible proteins and aeration studies. The Imperial College material also contains records of the creation, administration, finance and architectural design of the Biochemistry Department, and developments in the Department after Chain's statutory retirement in 1973. Additional information about Chain's research is available in the documentation of his very extensive consultancy agreements and collaborative work with industrial firms such as Astra, Beechams and Rank Hovis McDougall, and records relating to government, grant-giving and charitable bodies such as the British Heart Foundation, Cancer Research Campaign and Medical Research Council which contributed to the funding of his research. There is much material on Chain's lectures, addresses and broadcasts, and on his extensive travel on visits and conferences, which includes a substantial number of unpublished talks.

An exceptional feature of the Chain papers is the documentation of the large number of Israel and Jewish organisations with which he was associated, especially the Weizmann Institute of Science, where he was a governor for many years and had at one time considered taking up an appointment.

Sharpey-Schafer's correspondence is extensive. In addition to his own correspondence it includes papers of William Sharpey, saved by Sharpey-Schafer after his death, 1836-70 and n.d. There are significant numbers of letters from William Sharpey himself, Sir Michael Foster, Sir John Burdon-Sanderson, Sir William Osler, George John Romanes, Sir Victor Horsley, Sir James Paget, Lord Lister, Sir Charles Sherrington, Sir William Gowers, Thomas Henry Huxley, John Newport Langley, Sir Edwin Ray Lankester, Ernest Henry Starling, Allen Thomson, Sanger Monroe Brown, Sutherland Simpson, Francis Gano Benedict, Harvey Cushing, Albrecht Kossel, Karl Hugo Kronecker, Carl Ludwig, Charles Robert Richet, and Masaharu Kohima.

Material relating to Sharpey-Schafer's career at UCL includes correspondence on his controversy in the Neurological Society with Sir David Ferrier, 1887-88, and papers relating to the rebuilding of University College Hospital in 1895.

Material relating to Sharpey-Schafer's career at Edinburgh University includes correspondence on the forced resignation of William Cramer from the department of Physiology on grounds of German nationality, 1914, and papers on the opening of the department of Animal Genetics in 1930.

Other papers reflect various aspects of Sharpey-Schafer's scientific interests, including the history of the Physiological Society (with several letters from Archibald Vivian Hill), artificial respiration and bird migration. There are also numerous letters in response to his controversial address to the British Association in Dundee in 1912, and correspondence on the position of scientists in post-Revolutionary Russia, 1918-21.

There is a substantial correspondence on the various textbooks Sharpey-Schafer wrote or to which he contributed, 1910-34.

Sharpey-Schafer's personal papers include correspondence with his wives and children, 1876-1935, scrapbooks of press cuttings, c. 1899-1930, and a large collection of photographs, mainly portraits.

The records cover the period 1976-1993, although the majority of the records date from 1985-1993. Many sections of the archive are complete - minutes of the Executive Committee, 1985-1993; annual reports, 1986-1993 and newsletters, 1986-1993. The archive also contains a great deal of information relating to other cancer organisations, both in this country and abroad.

Although Barlow is best known for his original researches on infantile scurvy, there is very little material relating to that subject in the collection. There are manuscript drafts of his address to the Royal Medical Society of Edinburgh and his Bradshaw Lecture on infantile scurvy (BAR/E1-2), but the bulk of the clinical and scientific component of the papers relates to other matters, particularly Raynaud's disease and erythromelalgia, diseases to which Barlow turned his attention later in his career.

Among Barlow's clinical papers is a notebook recording minutes of a 'Clinical Club', 1875-77 (BAR/D.2), whose members included, apart from Barlow himself, Sidney Coupland, Rickman Godlee, William Smith Greenfield, Robert Parker, and William Allen Sturge.

Most of Barlow's private patients' records have not survived, though there is an index to his private patients' books, covering the years 1876-1918 (BAR/F.1).

Scientific and clinical matters are also discussed in Barlow's correspondence, but again this is relatively thin for the period when he was active in research. Barlow's non-family correspondence has clearly been heavily weeded: there are few letters from patients, with the exception of some prominent individuals, such as Mary Curzon, wife of Lord Curzon, Randall Davidson, archbishop of Canterbury, Lord Salisbury and Lord Selborne, and in general it seems that while letters from important or well-known figures have survived those from individuals deemed less important have been discarded. Significant numbers of letters remain however from several of Barlow's regular correspondents, such as the poet, Robert Bridges, Lord Bryce, and William Page Roberts, dean of Salisbury, as well as medical figures like Sir William Jenner and Sir James Reid.

Barlow's personal papers and family correspondence have survived in bulk and form a rich source of material for both his private and family life, and his public career. There are travel journals and sketchbooks from his earlier years, mainly documenting visits to the Continent, 1869-83; correspondence with his parents, brother, wife and children, 1852-1940, including letters written by Barlow from Balmoral, where he served as royal physician intermittently between 1897 and 1899, an eye-witness account of the death of Queen Victoria in 1901 (BAR/B.2/4), and letters and telegrams from court in 1902 during the crisis of Edward VII's appendectomy; and commonplace and scrapbooks compiled in retirement, 1920-37. Also from this period are various temperance notes and addresses.

The archive also comprises letters and papers of Barlow's parents, 1842-87; of Barlow's wife, Ada, including letters from her brother and sisters in India, 1858-80, and to her daughter Helen studying in Darmstadt, Germany, 1905-6; of Barlow's sons, Alan, Thomas and Basil, including letters from the last-named while serving on the Western Front, 1916-17; and notably of his daughter Helen, including correspondence with Archbishop and Mrs (later Lady) Davidson, 1910-35, and letters from Sir John Rose Bradford and his wife while serving in the Royal Army Medical Corps in France, 1914-19. Helen Barlow's papers also include records of three charities with which she was associated: the University College Hospital Ladies Association, 1900-50, the Southwark Boys Aid Association, 1914-36, and the Quinn Square [Southwark] Social Centre Society, c. 1935-1951. Finally there is a handful of letters to Andrew Barlow, Sir Thomas's grandson, mainly relating to articles he wrote about his grandfather, 1955-81.

The collection covers Lord Moran's life and career. It includes papers (committee minutes, correspondence, notes, printed material, ephemera, articles, parliamentary papers, etc.) re his position as Dean of St Mary's Hospital Medical School, 1920-1945; as President at the Royal College of Physicians, 1941-1950; his role in negotiations over the establishment and structure of the NHS, 1942-1960; as Chairman of the Awards Committee, 1948-1962. His other professional activities are covered in general correspondence files; a series of medical records, including material on Winston Churchill, 1944-1965; subject files relating to his role on various government, educational and medical bodies, including the commission to determine whether Rudolph Hess was mentally fit to stand trial in 1945. The collection includes drafts and papers re Anatomy of Courage (including photocopies of his World War I army notebooks), and Winston Churchill: Struggle for Survival. There is also a section of unpublished writings and speeches, 1921-1970. Papers consulted by Professor Lovell in Australia while writing his biography of Lord Moran, were returned in two batches, the first in April 1990, when he helped with the initial sorting and listing of the papers, and the second in April 1991. Some of these papers have been returned to the main body of the collection, however most have been kept in a separate section in the list (section L). The collection also contains personal and family material, photographs, press cuttings and ephemera, and a section comprising personal and professional papers of Lord Moran's wife Dorothy, Lady Moran (d.1983).

Records of the Cancer Research Campaign formerly the British Empire Cancer Campaign, covering all aspects of the Campaign's organization and activities. Sections A-C comprise committee minutes, agenda and papers, 1923-1976. The minutes of central headquarters committees are extensive, but there are serious gaps in the top level committees: Grand Council, the Executive Committee and the Scientific Advisory Committee. Efforts to locate the missing records have so far been unsuccessful. In addition, many minutes of sub-committees are either incomplete or unsigned copies. The collection contains very few records of regional branches; and information regarding either their existence or whereabouts is scant. The main body of the archive, Sections D-R, consists largely of files generated by Campaign headquarters, mainly the General Secretary's office. Files contain correspondence, reports, pamphlets, legal documents, press cuttings, articles, off-prints, posters, ephemera, etc. They cover the Campaign's history and organisation; senior members; relations with regional councils, branches, affiliatated bodies and other cancer organisations, both in the UK and overseas; cancer research and government provision; fund raising; research materials and equipment; cancer cures and causes; views and enquiries from the general public; cancer education and publications. There is also a series of press cuttings volumes, and three publicity films made in the 1950s.

Minute books, 1926-1927, and Annual reports, 1926-1938, of the Pioneer Health Centre Peckham, and volumes of press-cuttings about the Centre 1929-1961; files, publications and ephemera relating to the activities of the Centre, 1925-1952; files of the Pioneer Health Centre Ltd following the closure of the Centre, 1950-1999; books about the Centre; photographs, films and videos; papers of George Scott Williamson, 1910-1991, including personalia, correspondence, lectures, drafts of articles and books, notes; papers of Innes Hope Pearse, including personalia, correspondence, notes, manuscripts, drafts of The Quality of Life, reprints; materials relating to Scott Williamson and Pearse's research on pathology and the thyroid, including notes, lectures, manuscripts, correspondence, and reprints.

MSS.3259-3285 comprise chiefly scientific material; they include student notebooks on zoology, botany and geology (MSS.3259-3280); scientific logs from the British Antarctic Expedition (MSS.3281-3283), specifically a biological log (MSS.3281-3282) and a log of whales sighted (MS.3283), both spanning 1910-1913; an address delivered in 1913 to the New Zealand branch of the British Medical Association on Mendel's principle of heredity (MS.3284); and some notes on fish and fishing (MS.3285). MSS.5252-5254 comprise more personal and more miscellaneous material. MS.5252 is a scrapbook kept by Lillie, containing news cuttings, photographs and miscellaneous papers, spanning the period c.1845-1910 and including cuttings (with portrait prints) on science and scientists, 1845-1901; caricatures by Lillie of lecturers and staff at Birmingham University, 1904-1905; geological photographs, 1907-1909; family photographs (including a group class portrait at United Services' College, Westward Ho!, c.1892); and ephemera from Cambridge, 1909-1910. MS.5253 comprises cuttings from newspapers and illustrated magazines, spanning 1910-1914 and mainly relating to Robert Falcon Scott's British Antarctic Expedition. Finally MS.5254 comprises correspondence and very miscellaneous papers from the period 1824-1938 (plus some undated material) among them letters to his grandfather John Lillie D.D. (1806-1866), and to his maternal relatives the Macaire family, and letters to Lillie from E.A.N. Arber, Caroline Oates and others.

The bulk of the collection consists of correspondence: the Singers were clearly vigorous letter writers and both Charles and Dorothea had an enormous number of family, friends and acquaintances. Unfortunately many of their letters were hand written and very few carbon copies survive. Very occasionally an attempt at methodical selection and arrangement is evident: on the whole correspondence had been kept in alphabetical order, and this has been retained in the arrangement of the collection. Dorothea and Charles' correspondence was fairly mixed (reflecting their working life together) with the exception of two distinct groups: correspondence about Dorothea's research on alchemical manuscripts, and later correspondence about her hearing aids.

The main part of the collection centres on the correspondence; this has been grouped together in a self-evident sequence: writings and biographical personal papers follow. Certain of Dorothea's papers remained clearly distinct and these have been kept together. Section E contains a variety of material relating to Jewish refugees, which had been placed on one side by Dorothea after the war for permanent preservation. It has not been listed in detail but sorted into three broad categories. The last section, comprising additional correspondence of the Singers with Sir Zachary Cope, Sir Arthur Salusbury MacNalty and Dr F N L Poynter, is not strictly part of the collection, but these groups of correspondence were given to the Institute to be placed alongside the Singer papers.

The initial deposit, sections A-K, consists mainly of correspondence and associated papers (leaflets, memoranda, extracts from minutes, etc.). There are two main series of correspondence: 'People' and 'General' and some other distinct smaller series such as 'Branches and other Societies'. The internal arrangement of these files is normally chronological, with a few exceptions (usually an alphabetical arrangement). There are also lecturers' report sheets, publications, slides, posters, charts, and photographs, mainly but not exclusively in Section G: Propaganda and Publicity. There is a set of Annual Reports and related material 1908-1979 (Section A). Under the will of Dr. Marie Stopes the Eugenics Society was left her birth control clinic, books from her library and certain emoluments. Three boxes of her correspondence and some miscellanea, were assigned to section K. In 1988 minute books and the Society's extensive collection of press cuttings plus some financial records were added as GB0120 SA/EUG/L-N.

The papers consist almost entirely of biographical and personal material, memorabilia etc. covering the whole of Evans's career. Very little remains relating to his scientific research. Many of the documents were worked over by Evans during his retirement and bear his annotations, comments and reflections. Items B.1 and B.2 consist of photographs of Lovatt Evans and his collaborators, many of them identified and dated by Lovatt Evans. His book of press-cuttings (A.21) indexed and annotated, also contains material of interest relating to his colleagues and fields of study. There is material in section D. relating to Starling's Principles of human physiology, of which Evans edited the 2nd to 13th editions.

Records of the Family Planning Association from its inception as National Birth Control Committee in 1930, until the major organisational changes following the 1974 NHS Act; records of predecessor bodies subsequently assimilated; records of affiliated clinics, including substantial collection of records of the North Kensington Women's Welfare Clinic; papers of Margery Spring-Rice and of Caspar Brook; photographs, pamphlets, ephemera, posters

Papers cover Witkowski's writings on medical history (and other areas of history) rather than his medical activities. MSS.5036-5038 comprise press cuttings, publishers' notices, reviews, etc., relating to Witkowski's writings, plus original poems, some photographs, and some letters to him about his work; they span the bulk of his career (1865-1920). MSS.5039-5085 consist of material related closely to various published works on medical history and art history by Witkowski: typescript and holograph drafts, annotated published material, etc. Within this block of material, MSS.5057-5062 consist of a detailed critique of Folie de l'Empereur by Augustin Cabanès (1862-1928), consisting of heavily annotated copies of the published work. Also worth noting are MSS.5063-5064, copies of Witkowski's Comment j'ai appris l'Histoire Sainte, a Rabelaisian and satirical anti-clerical history. Finally, MSS.5086-5088, written under the pseudonym "Docteur Clam", comprise travel writings, recording travels in Italy, Turkey, Romania and Hungary, in 1901 (MS.5086); Egypt, in 1901-1902 (MS.5087); and Italy, in 1905 (MS.5088).