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The archive spans Browne's career from school onwards, but the core series of records focus on his work as a medical missionary at the BMS hospital in Yakusu, Belgian Congo (now the Democratic Republic of Congo). Section B comprises records for the period 1938-1958, including registers of leprosy sufferers, case records and photograph albums documenting various symptoms. Section K contains further photographs (mainly clinical) for the period 1938-1977, the most important series of which dates from Browne's time at the Baptist Mission Hospital and comprises over 900 negatives and prints together with supporting documentation, 1954-1958.

Section C contains a small number of files compiled by Browne during his research into leprosy, yaws, onchocerciasis and ainhum, 1946-1983. Particularly notable are the files on the anti-leprosy drug B663 (now known as clofazimine), into the use of which Browne conducted pioneering studies whilst director of the Leprosy Research Unit, Uzuakoli, Eastern Nigeria, 1959-1966.The remaining records comprise personal and biographical material, 1923-1985 (section A); general subject files containing correspondence, reprints etc. on a wide variety of topics, 1948-1986 (section D); writings by Browne, 1935-1985 (section E); records of Browne's involvement with the International Leprosy Association, 1909-1985 (section F) and various other organisations, 1959-1986 (section G); records on foreign visits, 1965-1985 (section H); and a few files on religious matters, 1959-1984 (section J).

Morrison and Hobson family papers, 1807-1963. The papers are the product of a period of considerable spiritual, cultural and political change in China. They are a significant source for study of the development of Protestant missions in China (in particular the role of the medical mission and the introduction of Western medicine), and also provide evidence of the involvement of the missionaries with issues of British trade and diplomacy.

MSS. 5827-5852: correspondence and papers, especially of the Revd Robert Morrison (1782-1834), missionary in China, 1807-1834; John Robert Morrison (1814-1843), Chinese interpreter, Colonial Secretary of the Hong Kong government; and Dr Benjamin Hobson (1816-1873), medical missionary in China, 1839-1859. The majority comprise personal and domestic correspondence of the Morrison and Hobson families and their friends, with less emphasis on official papers, although the collection includes letters on the Peacock expedition to Siam and Cochin China led by Edmund Roberts (1784-1836), United States merchant and diplomat, 1832 (MS.5830), and letters to Benjamin Hobson from leading missionaries. 1843-1862 (MS.5839). Insight into missionary work in China can be gained in particular from the letters of the Revd. Robert Morrison. MS. 7127: 'Domestic Memoir of Mrs Morrison', by the Revd. Robert Morrison, addressed to his children Mary Rebecca and John Robert Morrison (1814-1843), 5-7 January 1824. Mary Morrison, Robert's first wife, died of cholera at Macao on 10 June 1821. This memoir was compiled by Robert Morrison during the voyage home from China aboard H.E.I.C.S. Waterloo.

Papers of Henry Solomon Wellcome, 1800-1985, comprising articles, publications, financial records, legal records, administrative documents, property details, probate records, marriage and divorce records, diaries, microfiche of letter books, details of events, subscription lists, field and geological reports, press cuttings, photographs, ephemera, objects, and family papers dating back to 1800.