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The material focuses chiefly upon bibliography, comprising notes on writings about gymnastics and manipulative treatment, and Cyriax's collations of authors cited in various works on the subject. In addition to this there are some writings upon manipulative treatment itself and related issues (MSS.2001, 2006-2007), a syllabus of lectures to be delivered by Cyriax at the Central Institute for Swedish Gymnastics (MS.6054), writings on massage by authors other than Cyriax (MSS.6056-6059) and an acknowledgement by the Museum of Practical Geology for specimens presented by another member of the Cyriax family (MS.6060).

Papers of Sir Ludwig Guttmann covering most of his career, although there is relatively little on the earlier years in Germany before he emigrated with his family to the UK in 1939. There is some personal and biographical material, and a typescript autobiography. There are a number of items relating to Stoke Mandeville Hospital and its work in the rehabilitation of paraplegics, which Sir Ludwig pioneered. There is also some material, mostly photographs, relating to the International Paralympics which developed from his initiatives at Stoke Mandeville.

The collection comprises prescriptions issued by Kellgren at various institutes for Swedish medical gymnastics; namely, the Schwedisches Heilgymnastisches Institut in Gotha, Germany (MSS.5406-5407 and 7869), the Schwedisches Institut für Manuelle Behandlung der Krankheiten, Baden-Baden (MS.7872), the Swedish Institution for the Cure of Diseases by Manual Treatment, London (MSS.5408 and 7870), the Institutet för Manuel Sjukbehandling, Sanna, near Jönköping, Sweden (MS.5409), and the Institution Suèdoise pour le Traitement Manuel des Maladies, Paris (MS.7871). Patients include members of the nobility of the United Kingdom and of Germany, as well as members of the Kellgren and Cyriax families.

Two volumes of a manuscript diary, 1858-1859, recording the daily activities of James Patterson, a master at the Deaf and Dumb Institution, Manchester, run by his uncle. As well as the daily routine of teaching, Patterson describes his own studies at the School of Art, his interest in athletics and sports, communication with his family in Cornwall and a visit to London over Christmas 1858 (in which he walks about the city, visits the Colosseum, the Pantheon, the Crystal Palace at Sydenham and another establishment of that name at Great Portland Street, and witnesses some mesmeric experiments).

The material comprises notes, taken by Susan H. Cannon, of Wilson's lectures on pathology and the treatment of diseases by Swedish remedial gymnastics.