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The collection covers Lord Moran's life and career. It includes papers (committee minutes, correspondence, notes, printed material, ephemera, articles, parliamentary papers, etc.) re his position as Dean of St Mary's Hospital Medical School, 1920-1945; as President at the Royal College of Physicians, 1941-1950; his role in negotiations over the establishment and structure of the NHS, 1942-1960; as Chairman of the Awards Committee, 1948-1962. His other professional activities are covered in general correspondence files; a series of medical records, including material on Winston Churchill, 1944-1965; subject files relating to his role on various government, educational and medical bodies, including the commission to determine whether Rudolph Hess was mentally fit to stand trial in 1945. The collection includes drafts and papers re Anatomy of Courage (including photocopies of his World War I army notebooks), and Winston Churchill: Struggle for Survival. There is also a section of unpublished writings and speeches, 1921-1970. Papers consulted by Professor Lovell in Australia while writing his biography of Lord Moran, were returned in two batches, the first in April 1990, when he helped with the initial sorting and listing of the papers, and the second in April 1991. Some of these papers have been returned to the main body of the collection, however most have been kept in a separate section in the list (section L). The collection also contains personal and family material, photographs, press cuttings and ephemera, and a section comprising personal and professional papers of Lord Moran's wife Dorothy, Lady Moran (d.1983).

Papers of Dame Janet Vaughan, mainly 1939-1949, including material on her work with the Emergency Blood Transfusion Service, social and industrial medicine and post-War medical services, child guidance, Health Survey and Development Committee in India, and treating sufferers from starvation liberated from Belsen.