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Stratton was born in Manchester on 8 October 1913. He was educated at Central Manchester High School before winning scholarships to the University of Manchester in 1931. He graduated B.Sc. in 1934 and went on to study as a medical doctor, qualifying MB, ChB in 1937. He became MD in 1945. Stratton began work as a doctor in General Practice but in 1940, following the outbreak of war, he joined the Manchester Blood Depot. Initially he served as Medical Officer but was quickly appointed Deputy Regional Transfusion Officer. The post-war health service reforms saw the creation of twelve regional blood transfusion centres. Stratton was appointed Regional Blood Transfusion Officer and in 1949, when the Manchester Centre came under the Regional Hospital Board, Director of the North West Regional Blood Transfusion Centre (later the Manchester Blood Centre), a post he held to retirement in 1980.
He combined administrative, fund-raising and clinical responsibilities with active research in the area of blood group serology, making a particular contribution to the detection of blood group antibodies. In retirement he worked on antiglobulin reagents and haemagglutination, in association with D. Voak. In 1947 Stratton was appointed Special Lecturer in Human Serology at the University of Manchester. He was made Reader in 1967 and in 1977 was appointed to a Personal Chair. Stratton received a D.Sc. in 1957. Stratton was a Founder Fellow of the Royal College of Pathologists and a Fellow of the Royal College of Physicians. In the early 1980s he was a founder member and first President of the British Blood Transfusion Society. In recognition of his services in the field of blood transfusion Stratton was awarded the 1963 Oliver Memorial Award, the 1978 Karl Landsteiner Award of the American Association of Blood Banks and in 1987 received the British Blood Transfusion Society's highest honour, the James Blundell Award. Stratton died on 2 April 2001. He was survived by his wife Louisa and two sons.