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William Job Collins was born in London on 9 May 1859 and received his education from University College School, London and St. Bartholomew's Hospital. He became a Fellow, Scholar and gold medallist in Sanitary Science and in Obstetrics at London University and received Honours in Physiology, Forensic Medicine and Surgery. During his career Collins was also involved in many aspects of anatomy and ophthalmology, receiving the Doyne Medal for the latter from Oxford University in 1918. He was knighted in 1902.
William Job Collins was also Vice-Chancellor of the University of London, 1907-1909, 1911-12, and a member of the University Senate, 1893-1927. He was also a member of the Royal Commission on Vaccination, 1889-1896; Liberal Member of Parliament for West St. Pancreas, 1906-1910, and for Derby, 1917-18; London County Councillor for West St. Pancreas, 1892-1904; and Vice-Lieutenant of the County of London, 1925-1945.