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No biographical information is currently known about Samuel Holland. He attended lectures in Edinburgh in 1740, from the evidence of these notes of lectures by Charles Alston, and also the notes of lectures by Alexander Munro, Primus, held at the Wellcome Library.
Charles Alston was born at Eddlewood, Lanarkshire in 1685. He was educated in Glasgow, and after his father's death, the Duchess of Hamilton became his patron. He studied in Leiden under the Dutch physician Hermann Boerhaave (1668-1738), in 1715. He also met Dr Alexander Monro, primus (1697-1767). On his return to Scotland, Alston was appointed lecturer in Botany and Materia Medica in the Faculty of Medicine at the University of Edinburgh. He also became the King's Botanist and Keeper of the Garden at Holyrood. He held both of these posts until his death in 1760.