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The Children's Hospital Hampstead was founded in 1875 as a voluntary institution, situated in Maida Vale, and was originally called the Hospital and Home for Incurable Children. It took sick children up to the age of 16, whereafter they were returned to family and friends. It moved to College Crescent, Hampstead in 1904, and in 1919 changed its name to Northcourt Hospital and Home for sick children, in view of the fact that many diseases which a few years earlier would have rendered their sufferers incurable could be treated. In 1928 it was renamed the Hampstead Hospital for Children, and finally, in 1929, the name became the Children's Hospital Hampstead, to avoid confusion with Hampstead General Hospital.
At the outbreak of World War Two the hospital was requisitioned by the War Office. Throughout the war years various plans were proposed for its future use, including a merger with the Hampstead General, but these never materialised. The hospital joined the Royal Free Group when the NHS came into being in 1948, and the building was used firstly as the School of Nursing Preliminary Training School (PTS) and then as a nurses' home from then until its sale in 1990.