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These papers comprise the manuscript collection of F[rederick] Bacon Frank (1827-1911). They include a medieval medical miscellany (MS.550), material by or relating to the 17th century Yorkshire physician Nathaniel Johnston (MSS.3083-3086 and 6080), and some Bacon family administrative documents (MS.6079). One item relating to Nathaniel Johnston that did not form part of the Bacon Frank collection has been catalogued with it for convenience (MS.3086).

Two volumes of notes, on medical and chemical books, and on diseases and their treatment, c 1800-1823.

The collection chiefly comprises material generated whilst Sir Charles Blagden was a student at Edinburgh University: notes of lectures, clinical notes of cases observed at Edinburgh Infirmary, commonplace books, dissertation drafts, lists of materia medica, etc. Also included are two papers addressed to the Royal Society, 1767-1780.

The vast majority of the material relates to Dent's research and clinical interests and falls into four main categories: correspondence files; files created around the publication of papers; lecture notes and symposium papers; and case/research notes. There are also smaller quantities dealing with other aspects of his career, such as the administration of UCH Metabolic Ward. The papers thus reflect most of Dent's scientific and clinical interests. This research is mainly represented by the abstracted documentation which he kept with drafts of his published papers (see section E.1) and also by correspondence about cases and clinical case notes (see section C.5). To a lesser degree they also illustrate the work at the laboratory bench which underpinned much of this research. For example, a file of unidentified paper chromatograms has been preserved (C.2/10) to illustrate one of Dent's methods of working, as described by his colleague, Heathcote, and quoted in the Biographical Memoirs of Fellows of the Royal Society, 1978: 'Paper chromatograms were not to be thrown away. They were filed and, since the colours faded, the outline of each spot was drawn in and the intensity of the colour was indicated by a number.' The way in which Dent compiled a large series of files around drafts of scientific papers also illustrates the importance of the published paper to him as a stage in the research process. An incomplete collection of reprints of Dent's published papers may be found in section E.2 of the collection.

Essays by Peter Johnston Johnston-Saint, c 1927-1938, including 'The Herbal. The fore-runner of the pharmacopoeia in ancient and modern times', 'Healing Saints. A brief account of some of the Healing Saints to be found in Brittany' and 'Historical View of the Theory of Spontaneous Generation'.

Laufenberg's work on "Versehung des Leibs" followed by an anonymous "Practica" (assigned to Barthomolaeus Salernitanus). Original 15th century volume plus early 20th century transcript by its then owner, Theodor Engelmann.

Papers of Joshua Henry Porter including manuscript draft and published version of The Surgeon's Pocket-book, 2nd edition, 1880 and military scrapbook, 1850-1881.

Sharpey-Schafer's correspondence is extensive. In addition to his own correspondence it includes papers of William Sharpey, saved by Sharpey-Schafer after his death, 1836-70 and n.d. There are significant numbers of letters from William Sharpey himself, Sir Michael Foster, Sir John Burdon-Sanderson, Sir William Osler, George John Romanes, Sir Victor Horsley, Sir James Paget, Lord Lister, Sir Charles Sherrington, Sir William Gowers, Thomas Henry Huxley, John Newport Langley, Sir Edwin Ray Lankester, Ernest Henry Starling, Allen Thomson, Sanger Monroe Brown, Sutherland Simpson, Francis Gano Benedict, Harvey Cushing, Albrecht Kossel, Karl Hugo Kronecker, Carl Ludwig, Charles Robert Richet, and Masaharu Kohima.

Material relating to Sharpey-Schafer's career at UCL includes correspondence on his controversy in the Neurological Society with Sir David Ferrier, 1887-88, and papers relating to the rebuilding of University College Hospital in 1895.

Material relating to Sharpey-Schafer's career at Edinburgh University includes correspondence on the forced resignation of William Cramer from the department of Physiology on grounds of German nationality, 1914, and papers on the opening of the department of Animal Genetics in 1930.

Other papers reflect various aspects of Sharpey-Schafer's scientific interests, including the history of the Physiological Society (with several letters from Archibald Vivian Hill), artificial respiration and bird migration. There are also numerous letters in response to his controversial address to the British Association in Dundee in 1912, and correspondence on the position of scientists in post-Revolutionary Russia, 1918-21.

There is a substantial correspondence on the various textbooks Sharpey-Schafer wrote or to which he contributed, 1910-34.

Sharpey-Schafer's personal papers include correspondence with his wives and children, 1876-1935, scrapbooks of press cuttings, c. 1899-1930, and a large collection of photographs, mainly portraits.