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Although the collection is by no means comprehensive, there are interesting records of many aspects of Wilson's career.

Section A. Biographical: Brings together material relating to obituaries, tributes, honours and awards. Includes Wilson's account of his First World War experiences and his assessment of his scientific publications. Section B. Research: Although not extensive, provides documentation of a number of Wilson's principal interests including the Salmonella group of bacteria and milk hygiene. There are three laboratory notebooks with experimental data covering the period 1919-45. Section C. Public Health Laboratory Service (PHLS): Relates chiefly to the unpublished history written by Wilson after his retirement as Director of the PHLS. There is also a little material relating to laboratory design and equipment and PHLS personnel. Section D. Lectures and publications: The most substantial in the collection. There are records of Wilson's lectures for a period of forty years from 1944, extensive documentation of the later editions of Principles of bacteriology and immunity, and editorial correspondence and papers for the British Journal of Experimental Pathology and the Journal of Hygiene. Section E. Societies and organisations: Documentation of Wilson's association with ten British organisations including the Medical Research Club, Medical Research Council and Veterinary Club. The Medical Research Council material relates to the Working Party on Tristan da Cunha which was set up to supervise medical investigations when the inhabitants were evacuated to Britain after the island's volcano erupted in 1961. There is also material relating to the Research Foundation, Chicago, which specialised in tuberculosis research, on whose medical advisory committee Wilson served. Section F. Visits and conferences: Records of a number of overseas trips in an advisory capacity for the World Health Organisation, including to Ethiopia 1964, Iraq 1965, Iran, Sudan and Egypt 1971 and the Philippines 1972, and records of international microbiology congresses. Section G. Correspondence: Although not extensive, includes a chronological sequence of scientific correspondence, 1930-1987, Wilson's collection of autograph letters addressed to Topley and himself, and references and recommendations. Section H. Photographs: Photographic records of Wilson, colleagues, conferences and PHLS laboratories. Section J. 'Biographical History of Bacteriology': Manuscript of Wilson's history, with correspondence about publication.

The collection covers Lord Moran's life and career. It includes papers (committee minutes, correspondence, notes, printed material, ephemera, articles, parliamentary papers, etc.) re his position as Dean of St Mary's Hospital Medical School, 1920-1945; as President at the Royal College of Physicians, 1941-1950; his role in negotiations over the establishment and structure of the NHS, 1942-1960; as Chairman of the Awards Committee, 1948-1962. His other professional activities are covered in general correspondence files; a series of medical records, including material on Winston Churchill, 1944-1965; subject files relating to his role on various government, educational and medical bodies, including the commission to determine whether Rudolph Hess was mentally fit to stand trial in 1945. The collection includes drafts and papers re Anatomy of Courage (including photocopies of his World War I army notebooks), and Winston Churchill: Struggle for Survival. There is also a section of unpublished writings and speeches, 1921-1970. Papers consulted by Professor Lovell in Australia while writing his biography of Lord Moran, were returned in two batches, the first in April 1990, when he helped with the initial sorting and listing of the papers, and the second in April 1991. Some of these papers have been returned to the main body of the collection, however most have been kept in a separate section in the list (section L). The collection also contains personal and family material, photographs, press cuttings and ephemera, and a section comprising personal and professional papers of Lord Moran's wife Dorothy, Lady Moran (d.1983).

Records of Whiffen and Sons Ltd, founded by Thomas Whiffen (1819-1904), and of predecessor wholesale and manufacturing chemists, 1749-1971.

The collection centres on Wallich's work on biology, particularly marine biology, and his belief that other figures in the field were ignoring or plagiarising his discoveries. As well as his notes, it includes a collection of offprints by Wallich (MS.4969) and a collection of offprints by other scientists, with Wallich's comments (MS.4970).

Papers of Marthe Vogt, relating almost entirely to Vogt's scientific career, 1895-1988. Personal material is found in section A and includes a rare set of publications by her distinguished scientist parents Oskar and Cécile Vogt (A/1/2-4), a bibliography of Oskar Vogt (A/1/1), plus biographical information on Marthe Vogt (A/2) and various certificates of awards presented to her (A/3). Section B chiefly comprises notebooks and other papers relating to her experimental research, from Vogt's Berlin days through to the early 1980s. This research, meticulously recorded by Vogt, formed the background to many of her important and seminal papers in the field of neurotransmitters. The bulk of the collection is formed by Section C; 20 boxes of Vogt's correspondence covering all aspects of her work and career, chiefly from her arrival in Britain in 1935 up until 1988. This has been listed in detail and is arranged alphabetically by name of correspondent. Section D is a rather miscellaneous grouping of material relating to various aspects of Vogt's work. It includes papers and lectures on her adrenal research (D/1), lists of those who were sent reprints of her published articles (D/2), some ephemera relating to the Institute of Animal Research at Babraham (D/3), Vogt's University of Berlin doctoral thesis 1929 (D/4/1) and some book reviews written by her between 1952 and 1983 (D/4/2). The photographs comprising Section E include portraits of Vogt's father, mother and sister taken in Germany (E/1), an excellent collection of portraits of Marthe Vogt (E/2) and series documenting her attendance at conferences all over the world (E/4) and her many colleagues-friends and contacts (E/3).

Book of prescriptions by various hands. The date 1914 is found on p. 10, and 1937 on p. 59. Prices are added to some of the entries. Produced in London.

Collection of notes, extracts, translations, etc. from alchemical works: including also iatro-chemical receipts, alchemical, chemical, and technical processes, etc.: in French and Latin. Compiled by C. T., M.D. Illustrated with a few small and roughly executed pen-drawings of alchemical apparatus. There are also some grotesque heads and faces. Mainly written in a small and difficult current hand with many contractions. Pp. 260-343 in Vol. I are by another hand. Though mainly consisting of notes and anonymous extracts, processes, etc., the following may be separately mentioned: Vol. I. [Anon.] Traitté de la Grande Oeuvre (pp. 1-62). Basilius Valentinus. Enseignemans des Artifices concernant l'Ouvrage Universel ... et les Conclusions de tous ses escripts (86-113). Helmont (J. B. van). Imago firminti Liquor Alchaest (196-209). [Anon.] Stichiomantia. De li dadi: in Italian (210-213). Bernhardus Trevisanus. Responsio ad Thomam de Bononia: extract: in Latin (224-243) Glaser (C.). Annotations tirées de la Chimie de Glaser (306-322). Vol. II. Philaletha (E.). La confection du Grand Élixir métallique selon la pratique du Philalèthe conforme à celle du Cosmopolite et à la doctrine de Gebir (pp. 200-231). This seems to be a condensed version of the 'Enarratio methodica', 1678 by Eirenaeus Philaletha [cf. Ferguson: 'Bibliotheca Chemica', Vol. II, p. 191]. Copus (Martinus) [pseud. Cephalus (Arioponus)] Apotelesmata philosophica Mercurii triumphantis 1601: extract (358-371) [cf. Ferguson, op. cit., Vol. I, p. 150]. Albertus Magnus, St. Collectiones ex libro de animalibus, etc. (384-388). Densinger (A. B.). Geber ressuscité: an abbreviated version in French of the author's 'Geber redivivus' (394-406) [cf. Ferguson: op. cit., Vol. I, pp. 206, 207]. On p. 349 bis of Vol. II is a magical Hebrew 'Oratio angelica' written in Latin characters, there are other Latin charms, and one in French on p. 349. The compiler's initials are found on p. 178 of Vol. II in the form 'C.T.M.D.', and again on p. 279 of the same volume as 'C.T.d.m.'. There are several dates found in the second volume, the latest is 1683 on p. 26 and again on p. 27.

Prescription books of T Burden & Co.

Papers of the Strangeways Research Laboratory, c 1901-1988, comprising papers of T S P Strangeways; annual reports including 1929-1950; minutes and correspondence of the Trustees, 1929-1971; account books and ledgers, 1929-1970; papers relating to funding from various bodies, 1929-1975; papers relating to Medical Research Council funding, c.1962-1969; papers relating to grants, c.1963-1970 and c.1967-1980; administrative records, 1931-1971; general correspondence, 1942-1947, 1954-1956, and 1965-1970; assorted files, 1930s-1960s; miscellaneous historical material including research by George Eric Howard Foxon; minutes of the Radium Commission, 1932-1943; and papers relating to C F Robinow, E M Brieger and Michael Abercrombie.

Minute books of the Society of Apothecaries, 1629-1675.

Sharpey-Schafer's correspondence is extensive. In addition to his own correspondence it includes papers of William Sharpey, saved by Sharpey-Schafer after his death, 1836-70 and n.d. There are significant numbers of letters from William Sharpey himself, Sir Michael Foster, Sir John Burdon-Sanderson, Sir William Osler, George John Romanes, Sir Victor Horsley, Sir James Paget, Lord Lister, Sir Charles Sherrington, Sir William Gowers, Thomas Henry Huxley, John Newport Langley, Sir Edwin Ray Lankester, Ernest Henry Starling, Allen Thomson, Sanger Monroe Brown, Sutherland Simpson, Francis Gano Benedict, Harvey Cushing, Albrecht Kossel, Karl Hugo Kronecker, Carl Ludwig, Charles Robert Richet, and Masaharu Kohima.

Material relating to Sharpey-Schafer's career at UCL includes correspondence on his controversy in the Neurological Society with Sir David Ferrier, 1887-88, and papers relating to the rebuilding of University College Hospital in 1895.

Material relating to Sharpey-Schafer's career at Edinburgh University includes correspondence on the forced resignation of William Cramer from the department of Physiology on grounds of German nationality, 1914, and papers on the opening of the department of Animal Genetics in 1930.

Other papers reflect various aspects of Sharpey-Schafer's scientific interests, including the history of the Physiological Society (with several letters from Archibald Vivian Hill), artificial respiration and bird migration. There are also numerous letters in response to his controversial address to the British Association in Dundee in 1912, and correspondence on the position of scientists in post-Revolutionary Russia, 1918-21.

There is a substantial correspondence on the various textbooks Sharpey-Schafer wrote or to which he contributed, 1910-34.

Sharpey-Schafer's personal papers include correspondence with his wives and children, 1876-1935, scrapbooks of press cuttings, c. 1899-1930, and a large collection of photographs, mainly portraits.

Rogers' holograph manuscript. Volume 1 is entitled 'Obituaries of eminent persons'. Volume 2 (dated on the title 1847) is entitled 'Obituary of eminent persons and private friends', and is illustrated by 32 tinted photographs. Among the photographs are those of: Sir Charles Hastings (1774-1866); Sir William Jackson Hooker (1785-1865); and Sir Joseph Paxton (1804-1865). The volumes contain numerous biographies of doctors and scientists who died during the period of the record. The obituaries include various figures of Australasian interest such as Sir Stamford Raffles (1781-1826); Rev. Daniel Tyerman, missionary; George Bennet, missionary (fl.1812-1841); Rev. Thomas Slatyer, missionary, Samoa; and Colonel Robert Torrens (fl.1837).Each volume contains a stipple engraved portrait of the compiler, and his armorial book-plate.

Prescription books, account books, ledgers, and note book of chemists R Woollatt and J Boyd, 1880-1944.

The items in this collection relate to the work of the Real Expedición Botánica during the period 1790-1804 and particularly to issues of staffing and facilities. WMS/Amer.38 and 42 focus on the removal of the botanist Jayme Senseve for incompetence, his replacement by the physician José Mariano Mociño, his reinstatement and the issue of payment to Mociño for his work. WMS/Amer.44 relates to attempts by Martin de Sessé y Lacasta to gain space in the Hospital General de San Andrés to carry out tests upon indigenous drugs discovered by the expedition. WMS/Amer.43 summarises the achievements of the expedition with particular reference to their medical side.

Biographical material includes the draft of Mourant's autobiography, Blood and Stones published after his death in 1995, together with the correspondence and papers Mourant assembled while writing it. There is also documentation of Mourant's education at Victoria College Jersey and at Exeter College Oxford. The latter includes notes on lectures 1922 - ca 1926. Documentation of Mourant's career, honours and awards is patchy, although there is material relating to his search for employment in the early 1930s. There are pocket diaries spanning 1915-1982, with a fairly continuous sequence 1922-1961. Biographical material also includes extensive family and personal correspondence, much of which dates from or relates to the German occupation of Jersey or shortly thereafter. Mourant's other documented interests include his membership of the Methodist Church and his political affiliations, the League of Nations Union in particular.

There is a little material relating to Mourant's early career with the Geological Survey 1929-1931, miscellaneous material relating to Mourant's service with the MRC's Blood Group Reference Laboratory at the Lister Institute and the Nuffield (later Anthropological) Blood Group Centre at the Royal Anthropological Institute, London, and more extensive but uneven coverage of the Serological Population Genetics Laboratory. Although there is some documentation of the foundation of the Laboratory 1964-1965 and of its staff, the surviving material consists chiefly of correspondence and papers relating to Mourant's largely successful efforts to find continued funding for the Laboratory 1969-1977. Haematological research material, though not extensive, covers Mourant's work in a number of areas from research on blood serum in the mid-1940s to the mapping of blood groups in the 1960s and 1970s. There are early research notes, correspondence and papers relating to student and other expeditions undertaking blood group and physical anthropology research and some MRC material assembled by Mourant relating to projects in which he had an interest. The largest group of research papers, however, is maps and data produced during preparation of the second edition of The Distribution of the Human Blood Groups. There is a chronological sequence of drafts and correspondence relating to Mourant's publications, 1929-1991, with extensive material relating to editions of The Distribution of the Human Blood Groups and to The Genetics of the Jews (1978). There is also editorial correspondence relating to publishers and journals, chiefly invitations to review books or referee papers and an incomplete set of offprints. There is correspondence and papers relating to some of Mourant's lectures and broadcasts, most notably the lectures on blood groups given at the Collège de France, Toulouse, 1978-1979. Societies and organisations material is not extensive, and is confined to brief documentation of only a few of the societies and organisations with which Mourant was associated. It includes professional and geological bodies as well as haematological, biological and medical organisations. Visits and conferences material covers the period 1960-1987. It is not comprehensive, though there is also considerable documentation of Mourant's visits and conferences in the papers he assembled in the course of preparing his biography and with lectures material. Mourant's correspondence is extensive. Its complexity reflects Mourant's organisation of the material, the bulk of which was found in three main series: 'Foreign 1965-1977', 'Biological' and 'Geological', together with a fragment of a fourth series 'Home 1965-1977'. Principal correspondents include C.C. Blackwell, B. Bonné, O.J. Brendemoen, V.A. Clarke, L.L. Cavalli-Sforza, A. W. Eriksson, T.J. Greenwalt, J.K. Moor-Jankowski, T. Jenkins, W.S. Pollitzer, D.F. Roberts, J. Ruffié, D. Tills and J.S. Weiner.

Papers of the Medico-Botanical Society of London, 1815-1852, including correspondence letters and administrative papers of the Society, primarily relating to membership issues. In addition there are papers of John Frost (1803-1840), MS.7691 (4 items), relating either to botanical interests or the Medico-Botanical Society .

The records cover the period 1927-1993, although the majority date from the 1940s to the 1970s. Notable series include general correspondence with colleagues world-wide, 1935-1984; Dr Race's research papers on human genetic markers, late 1930s/early 1940s; files of correspondence, research notes, pedigrees etc. on blood grouping investigations, 1942-1993; and a comprehensive collection of photographs recording Medical Research Council Blood Group Unit staff at work and play, 1927-[1980s].

The collection provides good documentation of many aspects of McIlwain's career and his contribution to the development of neurochemistry in the UK and internationally.

Section A, Biographical, brings together obituaries, curricula vitae and bibliographies, and material relating to the various stages of McIlwain's scientific career, especially in the 1930s and 1940s, his appointment to the Biochemistry Chair at the Institute of Psychiatry in 1954 and the symposium held in his honour on his retirement in 1980. The section also presents a significant body of material relating to McIlwain's undergraduate studies at King's College, University of Durham, including essays and notebooks.

Section B, Institute of Psychiatry, is principally papers relating to the activities of McIlwain's own Department of Biochemistry and especially its teaching programme in neurochemistry. There is also material relating to various government and University of London enquiries into medical education.

Section C, Research, includes copies of McIlwain's M.Sc. and Ph.D. theses, notes, drafts and reports for early work in the 1930s and correspondence 'from the Lab' for the 1930s and 1940s.

Section D, Publications, lectures and broadcast, is the largest in the collection. It presents significant documentation, especially correspondence, relating to his textbook Biochemistry and the central nervous system which went through five editions, 1955-1985, and important editorial correspondence for the Biochemical Journal (member of the Editorial Board, 1946-1950), Biochemical Pharmacology and Journal of Neurochemistry. There are also drafts for lectures and seminars for scientific audiences in the UK and abroad, principally from the 1960s onwards.

Section E, Societies and organisations, documents McIlwain's involvement with a number of UK and international bodies including the Biochemical Society, the International Brain Research Organisation and the International Society for Neurochemistry (ISN) of which he was a founder member and from 1984 'Historian' of the Society with responsibility for its archives.

Section F, Visits and conferences, covers the period 1947-1993 and is of particular interest for its documentation of the historical sessions which McIlwain organised at ISN meetings.

Section G, Correspondence, presents an alphabetical sequence of McIlwain's correspondence including significant exchanges with a number of distinguished mentors and contemporaries such as G.R. Clemo, F. Dickens, K.A.C. Elliott, P.G. Fildes, S.S. Kety, H.A. Krebs, Derek Richter and F.L. Rose, and a chronological sequence of shorter scientific correspondence covering the period 1938-1992.

There is also an index of correspondents.

Papers of W J Manktelow, comprising notebooks compiled during the Chemist and Druggist Course at Brighton Technical College, Sept 1937-June 1938.

MSS.3259-3285 comprise chiefly scientific material; they include student notebooks on zoology, botany and geology (MSS.3259-3280); scientific logs from the British Antarctic Expedition (MSS.3281-3283), specifically a biological log (MSS.3281-3282) and a log of whales sighted (MS.3283), both spanning 1910-1913; an address delivered in 1913 to the New Zealand branch of the British Medical Association on Mendel's principle of heredity (MS.3284); and some notes on fish and fishing (MS.3285). MSS.5252-5254 comprise more personal and more miscellaneous material. MS.5252 is a scrapbook kept by Lillie, containing news cuttings, photographs and miscellaneous papers, spanning the period c.1845-1910 and including cuttings (with portrait prints) on science and scientists, 1845-1901; caricatures by Lillie of lecturers and staff at Birmingham University, 1904-1905; geological photographs, 1907-1909; family photographs (including a group class portrait at United Services' College, Westward Ho!, c.1892); and ephemera from Cambridge, 1909-1910. MS.5253 comprises cuttings from newspapers and illustrated magazines, spanning 1910-1914 and mainly relating to Robert Falcon Scott's British Antarctic Expedition. Finally MS.5254 comprises correspondence and very miscellaneous papers from the period 1824-1938 (plus some undated material) among them letters to his grandfather John Lillie D.D. (1806-1866), and to his maternal relatives the Macaire family, and letters to Lillie from E.A.N. Arber, Caroline Oates and others.

Personal papers and correspondence of John Coakley Lettsom, 1766-1812, including medical papers and pamphlets by Lettsom, newspaper cuttings relating to him, or subjects that interested him. Letters from various correspondents, mainly from the medical profession. The papers reflect his primary interests in 'Quacks and Quackery', clinical medicine, pathology, materia medica, variolation and vaccination. Many relate to the business of the Medical Society of London, of which Lettsom was President. There is also a fragment of an autobiography of his life as a as a student, MS.3245.

Letters received by Henry Lee, naturalist, 1866-1887.

Correspondence and miscellaneous papers of Dionysius Lardner including letters to Lardner from various correspondents and miscellaneous papers, mainly relating to his chair of natural philosophy at London University, and to the publication of the Cabinet cyclopaedia, 1827-29. Correspondents include John Brinkley, Bishop of Cloyne and astronomer, John Fleming, naturalist, Leonard Horner, Warden of the University, John Taylor, publisher, and contributors to the Cabinet cyclopaedia and an autobiographical memoir.

Records and collection of manuscripts of the Hunterian Society, 1676-1989. The manuscript collection includes extensive letters and papers relating to the Hunter and Baillie families.

Correspondence and papers of Sir Victor Horsley, 1883-1915, including notebook as Secretary to the Local Government Board inquiry into Pasteur's anti-rabies therapy, Apr-May 1886; papers and addresses by Horsley; letters to Horsley and miscellaneous papers, comprising papers relating to evidence given by Horsley to the Royal Commission on Vivisection, 1906-1907; an antivivisectionist postcard opposing Horsley as a parliamentary candidate (showing a banner with the head of a bulldog and the words 'Who said vivisection?'), Dec 1910; papers relating to Horsley's support for Christopher Addison, afterwards 1st Viscount Addison, at the Hoxton parliamentary election, January 1910; and a circular signed by Horsley as President of the National Temperance Federation, opposing the Army rum ration, 27 October 1914.

This small but important collection is concerned with the research and development of penicillin. Heatley's laboratory notebooks (A.1-3), October 1939-June 1941, and sketches and diagrams of apparatus, 1941 (C. 1-5) form the core of the collection. The famous experiment of 25 May 1941 on the 'Curative Effect of Penicillin' on mice is recorded in notebook A.2. There are also diary entries, narratives and explanatory notes, some prepared by Heatley expressly for the collection. The correspondence and reports exchanged between Heatley and Florey (section D.) is a set of photocopies, included to provide a complete account of the collaboration between the two on the penicillin project.

Harrods Pharmacy Department registers of prescriptions dispensed daily, Jul 1935-Jan 1977. There are gaps in the sequence between July 1936 and September 1938 and between December 1943 and April 1946, where the relevant registers were found to be missing on transfer to the Wellcome Archive.

Papers of Sir Ludwig Guttmann covering most of his career, although there is relatively little on the earlier years in Germany before he emigrated with his family to the UK in 1939. There is some personal and biographical material, and a typescript autobiography. There are a number of items relating to Stoke Mandeville Hospital and its work in the rehabilitation of paraplegics, which Sir Ludwig pioneered. There is also some material, mostly photographs, relating to the International Paralympics which developed from his initiatives at Stoke Mandeville.

Autograph letters and documents collected by George Grey Turner, 1647-1924. Details of the writers included can be found in the descriptions of the individual manuscripts.

Papers of William Gelder including letters from Gelder to his parents in Wakefield, while a dispensing and visiting assistant to [R Lucie] Reed, surgeon, at Whitechapel Road, London, Mar-Nov 1832, and while in Edinburgh in the employ of Mr Cope, a wholesale, retail and manufacturing chemist and druggist, Mar-Aug 1834. Notebook begun by Gelder in Edinburgh in 1834, and continued on a tour through Lancashire, the Isle of Man, Ireland and Wales in 1835, and in trade in Yorkshire, 1836-1837. Containing verses, commonplaces, orders for medicines and other goods, and miscellaneous notes. Signature inside front cover, 'William Gelder, Apothecaries' Hall, Edinbro, 1834.' On the rear end-papers is a coloured engraving of Apothecaries Hall.

Records of Fulham Road Pharmacy, Chelsea, including prescription books, 1887-1989, controlled drugs and poisons books, 1939-1978 and loose prescriptions 1953-1980.

Notes by Charles Friedel on chemistry and chemical substances, probably for lectures given as Professor of Organic Chemistry at the Sorbonne, Paris, after 1884 and miscellaneous papers, including a draft address, and letters and certificates concerning honours conferred on Friedel by the Chemical Society, by Oxford University, and by the Manchester Literary and Philosophical Society.

Correspondence between French naturalists and entomologists, 1816-1846.

Correspondence and papers of Sir Charles Fellows and Lady Fellows (1835-1871) and illustrations from Fellows' second expedition to Asia Minor. The papers primarily reflect Fellows' interest in research into Asia Minor - in particular the Lycian marbles.

The papers consist almost entirely of biographical and personal material, memorabilia etc. covering the whole of Evans's career. Very little remains relating to his scientific research. Many of the documents were worked over by Evans during his retirement and bear his annotations, comments and reflections. Items B.1 and B.2 consist of photographs of Lovatt Evans and his collaborators, many of them identified and dated by Lovatt Evans. His book of press-cuttings (A.21) indexed and annotated, also contains material of interest relating to his colleagues and fields of study. There is material in section D. relating to Starling's Principles of human physiology, of which Evans edited the 2nd to 13th editions.

Correspondence and papers of the statesman Henry Dundas both general and in his capacity as Commissioner (later President) of the Board of Control, 1783-1811.

The vast majority of the material relates to Dent's research and clinical interests and falls into four main categories: correspondence files; files created around the publication of papers; lecture notes and symposium papers; and case/research notes. There are also smaller quantities dealing with other aspects of his career, such as the administration of UCH Metabolic Ward. The papers thus reflect most of Dent's scientific and clinical interests. This research is mainly represented by the abstracted documentation which he kept with drafts of his published papers (see section E.1) and also by correspondence about cases and clinical case notes (see section C.5). To a lesser degree they also illustrate the work at the laboratory bench which underpinned much of this research. For example, a file of unidentified paper chromatograms has been preserved (C.2/10) to illustrate one of Dent's methods of working, as described by his colleague, Heathcote, and quoted in the Biographical Memoirs of Fellows of the Royal Society, 1978: 'Paper chromatograms were not to be thrown away. They were filed and, since the colours faded, the outline of each spot was drawn in and the intensity of the colour was indicated by a number.' The way in which Dent compiled a large series of files around drafts of scientific papers also illustrates the importance of the published paper to him as a stage in the research process. An incomplete collection of reprints of Dent's published papers may be found in section E.2 of the collection.

The papers consist primarily of Daly's meticulous records of experiments, covering the period 1919-1965, in a series of large notebooks, all indexed by him, some of which represent compilations of material gathered over many years from a variety of sources. There is also correspondence with, and biographical information regarding, several eminent physiologists including Sir Edward Sharpey-Schafer and Sir Charles Sherrington. William Sharpey is represented by five autograph letters to Sir Charles Lyell, 1858-1871.

Letters, reports and miscellaneous documents, mainly by Michel Chevreul, 1812-1881.

The papers are very extensive though there are some lacunae, probably attributable to Chain's many changes of workplace. The early biographical period is sparsely documented, there are sporadic gaps in the correspondence files, and there is no original documentation of the penicillin research at Oxford (although there are many historical accounts and much correspondence about the history of penicillin). The surviving biographical material provides documentation of the arrangements for Chain to live and work in Britain, later honours and awards and his musical interests, and family correspondence, photographs and press-cuttings. There are very substantial records of his later career at the Istituto Superiore di Sanità and Imperial College, London, including his continuing contributions to biochemical problems such as carbohydrate metabolism, ergot alkaloids, edible proteins and aeration studies. The Imperial College material also contains records of the creation, administration, finance and architectural design of the Biochemistry Department, and developments in the Department after Chain's statutory retirement in 1973. Additional information about Chain's research is available in the documentation of his very extensive consultancy agreements and collaborative work with industrial firms such as Astra, Beechams and Rank Hovis McDougall, and records relating to government, grant-giving and charitable bodies such as the British Heart Foundation, Cancer Research Campaign and Medical Research Council which contributed to the funding of his research. There is much material on Chain's lectures, addresses and broadcasts, and on his extensive travel on visits and conferences, which includes a substantial number of unpublished talks.

An exceptional feature of the Chain papers is the documentation of the large number of Israel and Jewish organisations with which he was associated, especially the Weizmann Institute of Science, where he was a governor for many years and had at one time considered taking up an appointment.

Reports of Thomas Lauder Brunton's lectures on therapeutics and notes from a lecture on chloroform with three fragments of lectures on eye affections, on the effects of alcohol, and the effect of drugs on the brain given at St. Bartholomew's Hospital, 1892-[1895].

Papers of Professor Leonard Jan Bruce-Chwatt, 1907-1989, comprising miscellaneous papers including World Health Organisation (WHO) reports, papers for his unpublished history of cinchona, and a translation of C Nicholle's Conquest of Infectious Diseases.

Correspondence of William Thomas Brande, 1825-1878, with some letters by his son, William T.C. Brande. Brande's advice on chemistry was sought by many of the correspondents in this small collection. They include Timothy Bramah on experiments relating to minting coin, Samuel Brown (1776-1852) on metal used in lighthouse construction; Frederick Richard Lees (1815-1897) on distillation of alcohol; Thomas William Clinton Murdoch (1809-1891) on fumigating 'coolie labour' aboard ship; and John Morillyon Wilson (1783-1868) on the danger of tobacco smoke to teeth. Other letters refer to publications and Royal Institution matters and Brande's own health.

Correspondence and papers of Alfred Bertheim, 1879-1914 including certificates, notes and letters to Bertheim from various correspondents, including Paul Ehrlich and Sahachiro Hata, Japanese bacteriologist, who also worked with Ehrlich. With drafts of out-letters.