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Records of B Hooper and Company, manufacturing chemists, including ledger, order, invoices, prescription books, formula book and labels for products.

Records of Howards and Sons, manufacturers of pharmaceutical chemicals, 1798-1950, including records relating to the formation of the company; records of partnerships; memoranda and articles of association; notices of resolutions; papers relating to formation of company in 1903 and its reconstruction in 1920; records of shareholders; records of debenture stockholders; Company seal and Board memorandum books.

Papers relating to property owned by the Company, including leases and related papers; insurance records; records of building work and plans of the laboratories and factories at Plaistow, Stratford and Ilford. Financial accounts and bank statements; records relating to staff including wages books and pension papers.

Papers relating to manufacture and trade including papers relating to patents, licences and agreements; records of experiments; records of stock, production and trade, including accounts, correspondence, price lists, advertisements and newscuttings and papers relating to exhibitions. Papers relating to the manufacture of quinine, including patents and agreements; records of production and trade, including records of supply of bark, accounts, technical and business reports, correspondence, price lists and newscuttings.

Records relating to subsidiary companies including Hopkin & Williams Ltd.

Hopkin and Williams Ltd., Thorium Branch; Thorium Ltd.

Hopkin and Williams (Travancore) Ltd.

Hatton Contract Co. Ltd. and Golden Eagle Syndicate; James Anthony and Co. Ltd.

Agatash Estates Ltd.

Barking and Ilford Navigation Co. Ltd.

British Camphor Co. Ltd.

Demerara Development Co. Ltd.

Drogueria de la Estrella Ltda., Buenos Aires; Methylators Ltd. and O. Wallis and Co. Ltd.

Papers relating to the Howard family and associates, including John Williams, Joseph Jewell, R. J. Law. Also photographs and drawings; and a collection of printed technical and historical works relating to the work of the company, including a history of the Company, biographies and local history.

Records of Stephen Green Limited, patent medicine manufacturer, 1780-1930. The records relate to proprietorship of the recipe for "Doctor Johnson's Golden Ointment" including legal documents and legal case papers; and records relating to the manufacture and sale of the ointment including financial accounts, order books, correspondence, sales summaries, testimonials, advertising, legislation involving patent medicines and history of the ointment. Also various family and estate records.

Pharmacopoeia of Guy's and Saint Thomas Hospitals inscribed J Langford Moore, and pharmacopoeia of the North Middlesex Hospital, Middlesex County Council, inscribed Jas Coutts.

London Oil and Tallow Trades Association records comprise: minutes, 1910-22 (Ms 23230-3); scrapbook of notices and letters etc, 1910-16 (Ms 23234); ledgers, 1921-67 (Ms 23235); and cash books, 1935-60 (Ms 23236).

Records of Smith Kendon Limited, 1826-1987. The collection mainly comprises the papers of Donald Smith and his capacity as Managing Director and Chairman of Smith Kendon Limited, including papers relating to the formation of the business such as articles of partnership and certificates of registration; deeds and other legal documents relating to property owned by the company; insurance policies; inventories; correspondence; minutes of meetings; Donald Smith's business diaries; sales figures; financial accounts; papers relating to stock and stock control; papers relating to sales; papers relating to products including recipe books; advertising; reports; staff records and papers relating to the Second World War.

Prescription books from 16 Jun 1745-25 Dec 1747 and 12 Nov1768-30 Nov 1769. The second volume contains entries for medicines prescribed for the Duke of Wellington, who was born at Mornington House, 24 Upper Merrion Street, Dublin on April 29, 1769. On the outside of the upper cover is a slip dated 17/8/1899, which states that the original earliest entry in the volume for 30 April 1769 has been cut out and framed for display in the shop at 49 Dawson Street, Dublin: another dated July 2 has also been cut out and 'given to Fielding Ould [?] Esqre' (i.e. Sir Fielding Ould, Dublin obstetrician, 1710-89). This manuscript still contains entries for the Countess of Mornington 2 May; 'Lord Mornington's young child', 4 May; 'The Countess of Mornington, the young child' 16 May; 'Lady Mornington, Master Frank Wesley, Young son', 25 May; 'The Hon. Master Arthur Wesley', 17 June. This last entry is also found for 2 July, 3 July, 6 July. According to the notice in the Oxford Dictionary of National Biography, Wellington used the form 'Wesley' for his name until 1798. Produced in Dublin.

Papers of Frederick Gardiner comprising short papers on dermatological subjects, and material for the third edition of Gardiner's Handbook of Skin Diseases.

Personal papers and correspondence of John Coakley Lettsom, 1766-1812, including medical papers and pamphlets by Lettsom, newspaper cuttings relating to him, or subjects that interested him. Letters from various correspondents, mainly from the medical profession. The papers reflect his primary interests in 'Quacks and Quackery', clinical medicine, pathology, materia medica, variolation and vaccination. Many relate to the business of the Medical Society of London, of which Lettsom was President. There is also a fragment of an autobiography of his life as a as a student, MS.3245.

Papers of Jean Nicholas Marjolin and his son René Marjolin, 1849-1894, including notes of Jean Nicolas Marjolin's lectures, by a medical student; letters from René Marjolin to his friend Edmond Dascols relating mainly to personal affairs, and the health of the Dascols family (with advice on cholera and other maladies) and letters from Paris at the time of the siege and the Commune, 1870-1871, when René Marjolin was active in treating the wounded prior to his arrest as a Bonapartist agent.

Holograph manuscripts of publications by Joseph von Schneller, notes, and some material by other persons collected by von Schneller, 1837-1885.

Book of prescriptions by various hands. The date 1914 is found on p. 10, and 1937 on p. 59. Prices are added to some of the entries. Produced in London.

Ledgers recording accounts for medical treatment and drugs dispensed, 1744-1799. Patients included, as well as private individuals, the Oxfordshire and Herefordshire militias, the poor of various parishes, and the local bridewell. On the front covers are annotations by Dr B E A Batt and his father Dr C D Batt, including the names of Edward Batt (1741-1797), surgeon and apothecary, and Augustine William Batt (1774-1847), MRCS Eng. Both practised in Witney.

Notebooks kept by three generations of the Carr family, William Carr (b 1715), of Settle, Yorks.; William Carr (1745-1821), apothecary to the Leeds Infirmary, 1774-1781, surgeon apothecary at Elland, Yorks., 1784, and later at Gomersal; and William Carr (1785-1861), general practitioner, of Gomersal.

Albums containing medical prescriptions written for members of Lord Kenyon's family. The prescriptions were written mainly by Sir Charles Herbert (d. 1855), and Arthur Noverre (1816-1878), FRCS.

These papers comprise the manuscript collection of F[rederick] Bacon Frank (1827-1911). They include a medieval medical miscellany (MS.550), material by or relating to the 17th century Yorkshire physician Nathaniel Johnston (MSS.3083-3086 and 6080), and some Bacon family administrative documents (MS.6079). One item relating to Nathaniel Johnston that did not form part of the Bacon Frank collection has been catalogued with it for convenience (MS.3086).

Records and collection of manuscripts of the Hunterian Society, 1676-1989. The manuscript collection includes extensive letters and papers relating to the Hunter and Baillie families.

Prescription books, account books, ledgers, and note book of chemists R Woollatt and J Boyd, 1880-1944.

Lecture notes and other papers of Sir Hermann Gollancz including notes from lectures on the philosophy of mind, given by George Croom Robertson (1842-1892) at University College, London; notes from lectures at University College, London, comprising lectures on applied mathematics by William Kingdom Clifford (1845-1879), and on physics by George Carey Foster. Also included are notes on the history of the Jews in Sicily; notes on aspects of Jewish religion and theology. Signature inside the front cover, 'H Gollancz, Jews' College' and medical prescriptions written for Sir Hermann Gollancz, and miscellaneous medical ephemera.

Papers of William Gelder including letters from Gelder to his parents in Wakefield, while a dispensing and visiting assistant to [R Lucie] Reed, surgeon, at Whitechapel Road, London, Mar-Nov 1832, and while in Edinburgh in the employ of Mr Cope, a wholesale, retail and manufacturing chemist and druggist, Mar-Aug 1834. Notebook begun by Gelder in Edinburgh in 1834, and continued on a tour through Lancashire, the Isle of Man, Ireland and Wales in 1835, and in trade in Yorkshire, 1836-1837. Containing verses, commonplaces, orders for medicines and other goods, and miscellaneous notes. Signature inside front cover, 'William Gelder, Apothecaries' Hall, Edinbro, 1834.' On the rear end-papers is a coloured engraving of Apothecaries Hall.

Prescription and invoice books of James Brocklehurst, chemist, 1835-1873.

Accounts for medicines supplied by Hallifax as Royal Apothecary to George, Prince of Wales (afterwards King George IV) and to the Prince of Wales' household. Both sets of accounts bear the signatures (on examination and approval) of Sir Richard Jebb, physician to the Prince, and Charles Fitzroy, 1st Baron Southampton, groom of the stole to the Prince. With signatures (on receipt of payment) of Robert Hallifax.

Prescription books of T Burden & Co.

Lecture notes, case notes and abstracts of printed works compiled by Lyon Falkener in various professional positions, 1861-1948: most importantly as locum tenens at Claybury Asylum and the Western Fever Hospital, Fulham, and as Assistant House Surgeon at the Metropolitan Hospital, London. A few personal items, largely testimonials and photographs supplement these, together with medical papers by Falkener. Falkener's later career as a general practitioner at Icart, Guernsey, is represented by a collection of his prescriptions.

Letters and papers of James Ormiston McWilliam, 1839-1862. The letters to McWilliam show the interest generated by his investigations into contagious diseases such as yellow fever, and his subsequent official reports. Other contemporary naval issues form a major part of the subject-matter, especially the working conditions and status of assistant surgeons, on whose behalf McWilliam campaigned.

Papers of Charles, Joseph and Jean Sédillot, medics, 1790-1875.

Recipe and account book with ownership inscription of Thomas Brigstocke Humphreys, Portmadoc, 1859. The book has later been used to accommodate newspaper cuttings (including several relating to members of the Humphreys and Brigstocke families, among them H. Humphreys of Aberystwyth, also a chemist, and various Humphreys in Llanelli) and ephemera. The latter relate to a wide variety of chemists' firms, chiefly in London; these include Corbyn and Co. (see MSS. 5435-5460).

Minute books of the Society of Apothecaries, 1629-1675.

Papers of Ann Gwendolen Dally and Peter John Dally, 1953-1991 including patient and other records of their joint private practice, plus Dr Ann Dally's correspondence with General Medical Council and writings relating to drug addiction.

The papers are very extensive though there are some lacunae, probably attributable to Chain's many changes of workplace. The early biographical period is sparsely documented, there are sporadic gaps in the correspondence files, and there is no original documentation of the penicillin research at Oxford (although there are many historical accounts and much correspondence about the history of penicillin). The surviving biographical material provides documentation of the arrangements for Chain to live and work in Britain, later honours and awards and his musical interests, and family correspondence, photographs and press-cuttings. There are very substantial records of his later career at the Istituto Superiore di Sanità and Imperial College, London, including his continuing contributions to biochemical problems such as carbohydrate metabolism, ergot alkaloids, edible proteins and aeration studies. The Imperial College material also contains records of the creation, administration, finance and architectural design of the Biochemistry Department, and developments in the Department after Chain's statutory retirement in 1973. Additional information about Chain's research is available in the documentation of his very extensive consultancy agreements and collaborative work with industrial firms such as Astra, Beechams and Rank Hovis McDougall, and records relating to government, grant-giving and charitable bodies such as the British Heart Foundation, Cancer Research Campaign and Medical Research Council which contributed to the funding of his research. There is much material on Chain's lectures, addresses and broadcasts, and on his extensive travel on visits and conferences, which includes a substantial number of unpublished talks.

An exceptional feature of the Chain papers is the documentation of the large number of Israel and Jewish organisations with which he was associated, especially the Weizmann Institute of Science, where he was a governor for many years and had at one time considered taking up an appointment.

Carbon copies of Martha Marquardt's transcripts of Paul Ehrlich's copybooks, 1898-1915, made by her during the early 1950s. There are 6 series, representing both copies of letters sent by him, and notebooks. There are not complete sets of transcripts for all of these: in some cases the originals themselves appear to no longer exist. Users should be aware that, according to a letter from Dr E A Underwood, Director of the Wellcome Historical Medical Museum, to Gunther Schwerin, 25 Mar 1963 (WA/HMM/CO/Eau/13), there are some misreadings by Marquardt of scientific terms in the originals, as, although she was capable of deciphering Ehrlich's writing, she was not herself a scientist. The originals are now in Boxes 4-22, 27-27A, 28-28A, 29-36 in the Paul Ehrlich Collection at the Rockefeller Archives Centre, and another set of transcripts in Boxes 80-86 there.

Papers connected with James Randal Hutchinson and William Henry Bradley's work in the Ministry of Health, 1890-1959 with some retrospective material, and small groups of papers of Sir Weldon Dalrymple-Champneys (on Brucellosis) and Dr J Allison Glover.

Papers of William Edward Van Heyningen, 1947-1978, including laboratory notebooks (bacterial toxins, dysentery, tetanus), 1947-1961; correspondence on cholera, 1967-1978, and tetanus, 1956-1974; miscellaneous reports and publications (mainly cholera).

Papers of Sir William Drummond Macdonald Paton, 1930-1993, chiefly comprising papers relating to his main research interests, namely underwater physiology, histamine, synaptic transmission, drug dependence, anaesthetic mechanisms, allergy electron microscopy and the history of science, particularly medical science. The collection also includes correspondence, research papers and laboratory notebooks, and papers relating to the committee work that occupied his energies. Papers from Paton's time as both a Rhodes Trustee and a Wellcome Trustee provide further evidence of the extent of his commitments in committee.

Papers relating to Paton's Chairmanship of the Research Defence Committee (1972-77) are particularly extensive and reveal the social and political pressures of the period, the passionate challenges of the anti-vivisection lobby, as well as Paton's personal commitment to a socially responsible use of animals in scientific experimentation. Papers relating to Man and Mouse: Animals in Medical Research (1984), in which Paton set out his fundamental position on animal experimentation, provide further material on this topic.

Another field of interest in which Paton expended considerable energy was that of drug dependence, particularly the pharmacological action of cannabis. Through work in laboratory and committees, and through the media and many speaking engagements, he campaigned strenuously to warn of what he judged to be the deleterious effects of cannabis, and forged campaign alliances with American colleagues who shared his concerns.

Throughout his career, Paton maintained strong links with the Royal Navy, acting as scientific adviser and consultant on deep diving and underwater physiology. This strand of his work was of enduring interest: Paton's work on the physiological properties of gases at high pressure led directly to the development of the deep-diving breathing mixture known as 'Tri-Mix', in which nitrogen is added to helium and oxygen. Paton took great pleasure in the Royal Navy achieving, in 1980, the world's deepest dive (see D/2/14).

Sargant was an outspoken supporter and practitioner of what he termed the 'practical rather than philosophical approaches' to the treatment of mental illness, pioneering and publicising various physical treatments and vociferously opposing the use of psychoanalytic techniques. The majority of the collection consists of his writings, both published and unpublished, supplemented by a small quantity of correspondence and other material. In addition, the collection contains clinical records for about 500 cases from Sutton Emergency Hospital in the 1940s. As well as covering clinical subjects (in Sections D, E, and F) and Sargant's views on the practice of psychiatry in general (Section B), the collection also contains material relating to his interest in the related issues of religious conversion and brainwashing (Section G).

Papers of the British Medical Association compring files [1915-1960], from the following subject series: Medico-Political, Science, Groups, Ethics, Public Health, Hospitals, Organisation. Also incomplete set of copy minutes of Council, Committees and of the Annual Representatives' Meetings and Special Representatives' Meetings, [1907-1982].

Bad trip to Edgewood consists of, interview transcripts, research files and videos for a television documentary on US Army testing of chemical and biological warfare agents on human 'guinea pigs' between 1955 - 1975, and includes files of mainly photocopied documents, reports, scientific articles, letters and newspapers articles, with some printed brochures, as well as videotapes. There is also a video copy of Bad trip to Edgewood which was produced by Michael Bilton, Yorkshire Television, and broadcast as a First Tuesday film in March 1993.

The files focus on secret projects carried out by the US Army Chemical Corps at the Aberdeen Proving Ground, Edgewood, Maryland USA, between 1955-1975, in which US Army volunteers were used to test the effects of lysergic acid diethylamide (LSD), benzilates such as BZ (3-quinuclidinyl benzilate, also known a QNB) and glycolates.

The testing programs were suspended in 1975 when information about them became public. A number of volunteers claimed to have suffered long term mental health effects from the tests. They also claim they were not informed at the time of immediate or long term effects of the agents tested. In 1977 US Army notified 686 volunteers who has been tested with LSD and conducted a follow up study of their health. The LSD follow-up study report released in 1980 found 'the majority of subjects evaluated did not appear to have sustained any significant damage from their participation in the LSD experiments'.

There are notes and transcripts of interviews conducted with former US Army personnel who were volunteers in the research programmes, individuals involved in the running testing programs, medical experts and lawyers.

Several files relate to particular law suits including that of Sgt James B Stanley, US Army, volunteer at Edgewood during 1958. In 1977 he was informed by the army that he had been given LSD as part of the testing program. In 1987 a controversial judgement by the US Supreme Court found against Stanley, effectually granting immunity from liability for money damages for all federal officials who intentionally violate the constitutional rights of those serving in the military.

Other notable cases frequently mentioned in the files include that of Frank Olson and Harold Blauer. Dr Frank R Olson, US Army scientist at Fort Detrick, apparently suicided, on 28 November 1953. In 1975 the Commission on CIA Activities within the United States (the Rockefeller Commission) revealed Olson had been given LSD without his knowledge while attending a meeting of Central Intelligence Agency (CIA) personnel eight days before his death. A civilian, Harold R Blauer died on 8 Jan 1953 after being given a lethal injection of Experimental Agent 1298 supplied by the US Army Chemical Corps to the New York State Psychiatric Institute where he was a patient. A 1975 Senate investigation revealed the facts of his death. Files also contain material on bacteriological testing by the Army and the CIA carried out in Washington DC, Florida, San Francisco, and New York. Particular reference is made to the case of Edward Nevin, a civilian, who died on 1 Nov 1950 in San Francisco as a result of a rare bacterial infection Serratia Marcescens, which coincided with a significant and unexplained outbreak of this infection between Oct 1950 and Feb 1951. In 1976 it was revealed that the US Army had conducted bacteriological warfare experiments with Serratia Marcescens over San Francisco Bay during September 1950.

There is a small amount of material relating to the role of American Citizens for Honesty in Government, a Church of Scientology sponsored organisation who campaigned during 1979 for a full investigation of the testing and storage of BZ and compensation for volunteers suffering long term effects from testing of the substance, and to chemical testing carried out in the UK at Porton Down, Wiltshire, UK and production of chemical agents at Nancekuke Base, Cornwall, and Anglo American cooperation in this area.

Copies of papers relating to his life and career and other family members, 1911, 1915, 1932, comprising: letter from Lt Col Sir George Roos-Keppel, Chief Commissioner and Agent to the Governor General, North West Frontier Province, to the Secretary to the Government of India, Foreign Department, reporting the capture of a party of raiders at Tarnab and commending various army and police officers, including Michael Donlea, Inspector of Police, North West Frontier (brother of Patrick), for their services in the incident, 2 March 1911; photograph [of raiders referred to in the above letter, 1911]; press cuttings describing charge of 21Lancers at Shabkadr, Aug 1915; brief typescript account of opium production and the organisation of Opium Department, United Provinces of Agra and Oudh, 1932; copy of letter to Mrs Lucy Sophia
Le Marchand (aunt by marriage of Patrick's wife) from Maj Cecil Allanson, 1/6 Gurkha Rifles describing the death of her son, Lt John Wharton Jones Le Marchand, Gallipoli, 1915.

'Report of Special Operational Store Tyburn, Jan-Nov 1945', by Marinus van den Ende (1912-1957), bacteriologist; and notes and photographs by Dr Helène E. Bargmann, PhD, FRZS, ATS (1897-1987), biologist.

The bulk of the papers are reports and talks reflecting Sir Weldon Dalrymple-Champneys' interests as a physician and wide range of duties as Deputy Chief Medical Officer of Health at the Ministry of Health. The subject files (section H) contain details, including some manuscript diaries, of work in which he was particularly closely involved, such as snake venom and brucellosis. Texts of talks and broadcasts, some extracted from those subject files, are brought together in section F. Section D includes personal letters from distinguished colleagues. Sections A-C include mementos of Sir Weldon's father, Sir Francis Henry Champneys (1848-1930), a pioneer of modern midwifery who was Physician-Accoucheur at St. Bartholomew's Hospital in London (1891-1913).

Papers of Professor Leslie Harold Collier including laboratory notebook re heat-stable smallpox vaccine, 1949, and 8 files of correspondence and papers re trachoma research, 1944-1971.

Personalia and memorabilia of Walter Ernest Dixon and G Norman Myers, 1865-1949; files relating to their pharmacological research (digitalis, morphine substitutes, coramine, etc) and teaching and glass lantern slides, some of Dixon and colleagues, mostly relating to research.

Records of Fulham Road Pharmacy, Chelsea, including prescription books, 1887-1989, controlled drugs and poisons books, 1939-1978 and loose prescriptions 1953-1980.

Papers of Herbert Davies Chalke, 1924-[1980] including lecture notes, papers and publications, including re alcoholism, TB, care of the elderly, and food safety. Also papers re service with RAMC in North Africa.

Harrods Pharmacy Department registers of prescriptions dispensed daily, Jul 1935-Jan 1977. There are gaps in the sequence between July 1936 and September 1938 and between December 1943 and April 1946, where the relevant registers were found to be missing on transfer to the Wellcome Archive.

Papers on a development by Henri Spahlinger of a controversial vaccine treatment for tuberculosis, 1909-1929, and press-cuttings relating to public reaction to his claims 1932-1939.

Reports and correspondence relating to the development of the drug Balsalazide, for treatment of people suffering from ulcerative colitis, 1979-1991.

Prescription books, ledgers, cash books, etc, of Nicholson and predecessor firms, 1893-1963.

This small but important collection is concerned with the research and development of penicillin. Heatley's laboratory notebooks (A.1-3), October 1939-June 1941, and sketches and diagrams of apparatus, 1941 (C. 1-5) form the core of the collection. The famous experiment of 25 May 1941 on the 'Curative Effect of Penicillin' on mice is recorded in notebook A.2. There are also diary entries, narratives and explanatory notes, some prepared by Heatley expressly for the collection. The correspondence and reports exchanged between Heatley and Florey (section D.) is a set of photocopies, included to provide a complete account of the collaboration between the two on the penicillin project.

Notes and photographs of experiment by John Edward French and Arthur Gordon Sanders at the Sir William Dunn School of Pathology, Oxford, concerning effect of cholesterol feeding on the liver, 1956.