Identity area
Reference code
Title
Date(s)
- [1934-2000] (Creation)
Level of description
Extent and medium
130 records management boxes
Context area
Name of creator
Biographical history
In 1936 Eliot Slater obtained a Medical Recearch Council grant to set up a twin register. In 1948 that led to a system at the Maudsley Hospital by which every patient was asked if they were born a twin and if they were, their names went on a register. The resulting Maudsley Twin Register formed the basis of much high quality research. This included a key monograph on the genetics of schizophrenia by Irving Gottesman and James (Jerry) Shields as members of the Psychiatric Genetics Unit. They argued the probabilistic rather than deterministic role of gender and were the first to apply a genetic - environmental multifactorial threshold model in modern psychiatry. In 1969 Slater retired and the Psychiatric Genetics Unit closed but research continued under Shields. Following his death in 1978 a section on psychiatric genetics was established within the Department of Psychiatry at the Institute of Psychiatry, based at the Maudsley, under the leadership of Professor Robin Murray. Successive studies of adult and child twins, drawing on the Twins Register, have and continue to shed light on the epidemiology and genetic and environmental causes of or impact on schizophrenia and other personality disorders.
Repository
Archival history
GB 0100 KCLCA IOP/TWIN [1934-2000] Collection (fonds) 130 records management boxes Institute of Psychiatry
In 1936 Eliot Slater obtained a Medical Recearch Council grant to set up a twin register. In 1948 that led to a system at the Maudsley Hospital by which every patient was asked if they were born a twin and if they were, their names went on a register. The resulting Maudsley Twin Register formed the basis of much high quality research. This included a key monograph on the genetics of schizophrenia by Irving Gottesman and James (Jerry) Shields as members of the Psychiatric Genetics Unit. They argued the probabilistic rather than deterministic role of gender and were the first to apply a genetic - environmental multifactorial threshold model in modern psychiatry. In 1969 Slater retired and the Psychiatric Genetics Unit closed but research continued under Shields. Following his death in 1978 a section on psychiatric genetics was established within the Department of Psychiatry at the Institute of Psychiatry, based at the Maudsley, under the leadership of Professor Robin Murray. Successive studies of adult and child twins, drawing on the Twins Register, have and continue to shed light on the epidemiology and genetic and environmental causes of or impact on schizophrenia and other personality disorders.
Received from the Institute of Psychiatry in two accessions, Jan and Sep 2006.
Papers reflecting a series of studies of twins utilising the Maudsley Twin Register, 1932-1999, reflecting the respective impacts of genetics and environment on a range of psychotic disorders, notably schizophrenia. Records include patient files/notes, 1932-1998; patient study profiles arising from tests, questionnaires and comments, 1948-1998; administrative records relating to funding applications to the Medical Record Council, ethical approval, and recruitment of subjects, 1948-1998. Studies include Opposite Sex Twin Study, Kendall Depressives Twin Study, Multiple Psychotic Families Twin Study, Maudsley Adult Twins Study, Anxious Twins Series, Personality Disorder Twin Study, Separated Twin Study, Psychotic Twin Studies, and the Gottesman and Shields series of studies on schizophrenia. The work of Professor Robin M Murray, Dr Adrienne M Reveley, Dr Alison M MacDonald and R Fulrich are also particularly reflected in the files.
Awaiting arrangement.
The collection contains sensitive personal information and medical details, apply to the Director of Archives and Information Management, King's College London, for details on access.
The collection contains sensitive personal information and medical details, apply to the Director of Archives and Information Management, King's College London, for details on reproductions.
English
No additional finding aids.
Institute of Psychiatry, Familial and Environmental Factors in Functional Psychosis Study (ref: IOP/FAM)
Twins' Early Development Study (TEDS)(ref: IOP/TEDS).
Entry compiled by Sarah Drewery, 2008.
Compiled in compliance with General International Standard Archival Description, ISAD(G), second edition, 2000; National Council on Archives Rules for the Construction of Personal, Place and Corporate Names, 1997.
Jan 2008 Psychoses Psychiatry Psychopathology Mental diseases Personality disorders Pathology Diseases Schizophrenia Medical research Murray , Robin M , Professor of Psychiatry Institute of Psychiatry
Immediate source of acquisition or transfer
Received from the Institute of Psychiatry in two accessions, Jan and Sep 2006.
Content and structure area
Scope and content
Papers reflecting a series of studies of twins utilising the Maudsley Twin Register, 1932-1999, reflecting the respective impacts of genetics and environment on a range of psychotic disorders, notably schizophrenia. Records include patient files/notes, 1932-1998; patient study profiles arising from tests, questionnaires and comments, 1948-1998; administrative records relating to funding applications to the Medical Record Council, ethical approval, and recruitment of subjects, 1948-1998. Studies include Opposite Sex Twin Study, Kendall Depressives Twin Study, Multiple Psychotic Families Twin Study, Maudsley Adult Twins Study, Anxious Twins Series, Personality Disorder Twin Study, Separated Twin Study, Psychotic Twin Studies, and the Gottesman and Shields series of studies on schizophrenia. The work of Professor Robin M Murray, Dr Adrienne M Reveley, Dr Alison M MacDonald and R Fulrich are also particularly reflected in the files.
Appraisal, destruction and scheduling
Accruals
System of arrangement
Awaiting arrangement.
Conditions of access and use area
Conditions governing access
The collection contains sensitive personal information and medical details, apply to the Director of Archives and Information Management, King's College London, for details on access.
Conditions governing reproduction
The collection contains sensitive personal information and medical details, apply to the Director of Archives and Information Management, King's College London, for details on reproductions.
Language of material
- English
Script of material
- Latin
Language and script notes
English
Physical characteristics and technical requirements
Institute of Psychiatry, Familial and Environmental Factors in Functional Psychosis Study (ref: IOP/FAM)
Twins' Early Development Study (TEDS)(ref: IOP/TEDS).
Finding aids
No additional finding aids.
Allied materials area
Existence and location of originals
Existence and location of copies
Related units of description
Publication note
Notes area
Note
Alternative identifier(s)
Access points
Subject access points
Place access points
Name access points
Genre access points
Description control area
Description identifier
Institution identifier
Rules and/or conventions used
Compiled in compliance with General International Standard Archival Description, ISAD(G), second edition, 2000; National Council on Archives Rules for the Construction of Personal, Place and Corporate Names, 1997.
Status
Level of detail
Dates of creation revision deletion
Language(s)
- English