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Thomas Keate was born in 1745. He studied as a pupil at St George's Hospital, London, and then became an assistant to John Gunning, surgeon to the Hospital. In 1792, the position of surgeon became available to succeed Charles Hawkins, which was sharply contested by Keate and Everard Home. Keate was elected as surgeon. In 1793 he succeeded John Hunter as surgeon-general to the Army, he was an examiner at the Royal College of Surgeons from 1800, and Master of the College in 1802, 1809, and 1818. As a surgeon he was the first to tie the subclavian artery for aneurysm. However, his reputation at St George's Hospital for not being punctual and being negligent in his duties, caused him to resign his post in 1813. Keate was surgeon to the Prince of Wales (later George IV), and also surgeon to the Chelsea Hospital, where he died in 1821. Keate published Cases of Hydrocele and Hernia (London, 1788), and several controversial papers such as Observations on the Fifth Report of the Commissioners of Medical Enquiry (London, 1808).