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Born 1841, Hafod, Wales, and brought up on the family farm in Pembrokeshire; apprenticed to a local apothecary; aged nineteen moved to London, worked at a chemist in Streatham and then as dispenser to the German Hospital; attended German lectures at University College London; moved to Aberdeen where he qualified in 1867; Army Medical School at Netley, Hampshire, 1868, where at the end of the four-month course passed out first on the list; posted to India in 1869, where he investigated cholera; while studying chyluria (the presence of lymphatic fluid in urine), he discovered minute worms in the urine of one particular patient - subsequently they were identified as Filariidae; in 1872 Lewis found similar worms in a blood sample and when this work was written up Lewis was amazed to discover the original patient setting up the type for its publication by the Government Printing Office in Calcutta. Later he found the mature worm but it had already been discovered independently of him by Joseph Bancroft in Australia. However he discovered and described the first trypanosome, which was named Trypanosoma lewisei after him, in the blood of a mammal; appointed, 1883, Assistant Professor of Pathology at Netley where he introduced practical bacteriology to the curriculum; died of pneumonia, 1886, allegedly as a consequence of a laboratory accident.