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In 1925, the Mott Clinic, a special unit for malaria therapy, was established at Horton Hospital, Epsom, Surrey. Patients were treated by infection with one or other species of malaria parasite, and the centre was responsible for providing infective material for use in hospitals throughout Great Britain and Ireland. The Mott Clinic became known as the Ministry of Health Malaria Laboratory, until [1952] when it became the Malaria Reference Laboratory. It was under the umbrella of the newly established Public Health Laboratory Service. P G Shute was Assistant Director of the Laboratory, 1944-1973, with Sir Gordon Covell as its Director. The Laboratory later moved from Epsom to the London School of Hygiene and Tropical Medicine, becoming known as the Health Protection Agency Malaria Reference Laboratory.