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Born Great Yarmouth, 1814; educated at a private school, Yarmouth; apprenticed to Charles Costerton, surgeon, in Yarmouth, 1830; entered as a student at St Bartholomew's Hospital, 1834; identified the parasite Trichina spiralis whilst studying at the hospital, 1835; clinical clerk to Dr Latham, 1835-1836; member, Royal College of Surgeons, 1836; sub-editor of the Medical Gazette, 1837-1842; Curator of the museum, 1837 and Demonstrator in morbid anatomy, 1839-1943, St Bartholomew's Hospital; Fellow, Royal College of Surgeons of England, 1843; Lecturer on general anatomy and physiology, 1843 and Warden of the College for students, 1843-1851, St Bartholomew's Hospital; prepared a catalogue of the anatomical museum of St Bartholomew's Hospital, 1846; prepared a catalogue of the pathological specimens in the Hunterian Museum of the Royal College of Surgeons of England, 1846-1849; Arris and Gale Professor of Anatomy and Surgery, 1847-1852; Assistant Surgeon, 1847-1861, St Bartholomew's Hospital; Fellow, Royal Society, 1851; Surgeon-Extraordinary to Queen Victoria, 1858; member of the Senate, University of London, 1860; lectured in physiology, 1859-1861, Surgeon, 1861-1871 and Lecturer on Surgery, 1865-1869, St Bartholomew's Hospital; member, 1865-1889, Vice-President, 1873, 1874, President, 1875, of the Council, Royal College of Surgeons; Serjeant-Surgeon-Extraordinary to Queen Victoria, 1867-1877; Consulting Surgeon, St Bartholomew's Hospital, 1869; President, Clinical Society, 1869; created Baronet, 1871; President, Royal Medical and Chirurgical Society, 1875; representative of the Royal College of Surgeons at the General Medical Council, 1876-1881; Serjeant-Surgeon to Queen Victoria, 1877; Hunterian Orator, 1877; President, International Congress of Medicine, 1881; Bradshaw Lecturer, 1882; Vice-Chancellor, University of London, 1883-1895; Morton Lecturer, 1887; President, Pathological Society of London, 1887; died, London, 1899.