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Pasteur's research on fermentation and rabies led to his discovery that most infectious diseases are caused by germs, the 'germ theory of disease'. He invented pasteurisation and his work became a key influence on developments in bacteriology and microbiology as well as in gerenal medical practise; The Pasteur Institute was founded in 1887 by Louis Pasteur; Louis Pasteur's grandfather was Jean Henri Pasteur, and his aunt Jeannette Pasteur, were both of Vuillafans, near Besançon. A cousin, Maximien Buchon, was of Salins;
Magnan family correspondence includes letters Marie and Louise Pasteur, Jules Raulin, Eugène Magnan, and Mathilde Magnan (afterwards Fournery); Jules Raulin (1836-1896), was Pasteur's first assistant, afterwards Sous-Directeur of Pasteur's Laboratoire de Chimie Physiologique at the Ecole Normale and Professor of Chemistry at Lyons. 1862-1884 and n.d; Louis Pasteur's assistant Fernand Boutroux, was the brother of Jeanne Pasteur; Henry Debray (1827-1888) and Eugène Viala were also assistants to Pasteur; Jules Vercel was a school friend of Pasteur's from Arbois.