Paton , Sir , William Drummond Macdonald , 1917-1993 , pharmacologist MacIntosh , F C

George Lindor Brown was born in Liverpool on 9 February 1903, son of George William Arthur Brown, schoolmaster in Warrington, and Helen Wharram. He attended Boteler Grammar School in Warrington, and entered the University of Manchester on a scholarship to study medicine, where A V Hill, the Nobel Prize winner, was his Professor of Physiology. He took an honours B.Sc. in physiology in 1924, then won the Platt Physiological Scholarship which enabled him to do research with B A McSwiney, earning an M.Sc. (1925). He qualified in Medicine in 1928 (MB, Ch.B Manch.), winning the Bradley Prize and medal for operative surgery. He joined McSwiney as lecturer in physiology at Leeds University in 1928, taking six months' leave to work in Sir C S Sherrington's laboratory at Oxford, and collaborating with J C Eccles. In 1934 Sir Henry Dale offered, and Brown accepted, a post at the National Institute for Medical Research in Hampstead, where he worked with (Sir) John Gaddum and W S Feldberg establishing the cholinergic theory of chemical transmission. In 1942 the Royal Naval Personnel Research Committee was established, and he became involved very successfully with diving and underwater operations, remaining Secretary to the RNPRC until 1949, and then its chairman until 1969. In 1949 he accepted the Jodrell Chair of Physiology at University College London, where he strenghthened the physiology and biophysics departments under (Sir) Bernard Katz and worked with J S Gillespie on adrenergic transmission. He served on various Royal Society committees, becoming Biological Secretary, 1955-1963. In 1960 he accepted the Waynflete chair of physiology in Oxford, becoming a Fellow of Magdalen. He also became a member of the Franks Commission of Inquiry into the working of Oxford University. In 1967 he resigned his chair to be elected Principal of Hertford College Oxford, although he continued with his research group in the pharmacology department. He was responsible for inaugurating the College's major apeal, negotiated two senior research fellowships, and dealt lightly with student restiveness. He married in 1930 Jane Rosamond, daughter of Charles Herbert Lees, FRS, Professor of Physics in the University of London and Vice-Principal of Queen Mary College, and had one daughter and three sons.