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The Royal College of Chemistry was established in 1845 in Hanover Square, London, with the first Professor August von Hofmann, and 26 students, the result of a private enterprise to found a college to aid industry. The College transferred to Oxford Street in 1848. In 1853 the College was incorporated with the Government School of Mines and of Science Applied to the Arts, effectively becoming its department of chemistry. Chemistry was one of the departments to be transferred to South Kensington in 1872.
The Royal College of Science was formed in 1881 by merging some courses of the Royal School of Mines with the teaching of other science subjects at South Kensington. In 1907 the Royal School of Mines and the Royal College of Science were incorporated in the Royal Charter of Imperial College of Science and Technology.