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Leslie R. Wolfson was born in March 1911. Between 1928 and 1932 he attended the Liverpool Dental School of Liverpool University, and in 1933 he bought a small dental practice at Priory Road, Anfield, Liverpool, where he worked until August 1934. He then became employed by the Co-operative Dental Association, being placed in charge of a surgery at Enfield Wash, Middlesex.
In 1935 he married Dr. Estelle Roekin and they moved to 1 The Grangeway, Grange Park, Winchmore Hill N21 where Dr. Roekin set up in medical practice. However, due to illness she had to close the practice in 1944. Mr. Wolfson opened his own dental practice in the vacant rooms at Grange Park. He was asked to help Mr. Grimshaw, a registered dentist, who had fallen ill, and worked partly at 340 Baker Street, Enfield. By 1949 Mr. Grimshaw became to ill to work and Mr. Wolfson eventually bought the practice from him, thus transferring his whole practice from Grange Park to Baker Street. He remained there doing only National Health work until his retirement in 1978.