The collection is divided into four main groups: The first group contains papers relating to William Clift's work as conservator of the Hunterian Museum. This is the largest of the four groups and contains a number of sub divisions such as explanation and display of specimens, expanding the collections, administration of the museum, and correspondence. This group also contains the transcripts made by Clift and others of the Hunterian manuscripts. The second group contains work carried out by William Clift as an illustrator for publications. The third group contains a small amount of personal material that is in the collection. The fourth group contains transcripts and copies of manuscript material by William Clift that is held in other repositories such as the Natural History Museum.

Papers of Sir William Henry Flower, [1845-1883], comprising papers largely created and compiled as Curator of the Hunterian Museum of the Royal College of Surgeons of England, relating to a collection of birds' eggs, undated; rough list of contents of store bottles, undated; payments for expenses on specimens for the Museum during 1802-1861, 1861; list of additions purchased for the Museum during 1806-1862, [c1862]; summary of principal duties and occupations of museum officers and servants in the absence of the Conservator, undated; salaries and wages for the museum department, 1861; list of specimens presented by Dr Andrew Murray, 1865; list of specimens presented to the Museum by W L Crowther, [1868]; report on the Hunterian documents held by the Royal College of Surgeons of England, 1868; report on the state of the physiological series in the museum, 1869; description of pathological specimens from the bodies of soldiers who died insane, forwarded by Dr William Julius Mickle, 1876; list of preparations from the College Collection, 1876; list of total numbers of preparations in the Museum, 1877.

papers relating to preparations of specimens, duties of Royal College of Surgeons of England, museum staff; catalogues of physiological and pathological specimens; letter to Alban Doran; correspondence with Thomas Stone; correspondence with Edward Shuter, 1845-1883.

Papers of Sir Astley Paston Cooper, [1800-1825], comprising volume of notes on his lectures on surgery, delivered at St Thomas's Hospital, taken by an unidentified student, [1814-1825] (G/PP2/8), with loose manuscript notes ((G/PP2/9);

three volumes of notes on his lectures on surgery, taken by an unidentified student, [1813-1825] (G/PP2/10-12);
notes on his lectures on fungoid testis, taken by an unidentified student {G/PP2/13);
prescription for chilblains, attributed to Sir Astley Cooper, undated, with letter concerning authenticity, 1993 (G/PP2/13b).

Papers and photographs of Mary Frances Lucas Keene, 1911-1994, comprising:
Personal papers, including diplomas and certificates awarded to Lucas Keene, 1904-1973; personal correspondence including letters from the RFHSM and the University of London, mainly concerning her retirement, and appointment as Emeritus Professor, 1950-1975; letters from Lucas keen to Prof John W S Harris and his wife, Sonia, 1971-1978; notes for speeches, mainly given at London (RFH) School of Mediicine for Women ceremonies, 1933-1954; papers on anatomy teaching and research, including notes, diagrams and photographs, 1921-1951; notebooks containing case notes on dissections of human embryos and foetuses, 1921-1951; Emphemera including Royal Free Hospital Pharmacopoeia and Journal of tje Medical Women;s Federation, July 1951, containing an appreciation of her work; photographs of Lucas Keene, her family and fiends, 1924-1974; group photographs of Anatomical Society meeting, Edinburgh, 1947 and Staff and Students of RFHSM, 1950; album of photographs of the medical school, staff and students, presented to Lucas Keene on her retirement as Professor of Anatomy, 1951

Sir James Paget's index to references for medical biographies, intended for the Biographical Dictionary of the Society for the Diffusion of Useful Knowledge (1842-44), c.1844.