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Lecture notes, case notes and abstracts of printed works compiled by Lyon Falkener in various professional positions, 1861-1948: most importantly as locum tenens at Claybury Asylum and the Western Fever Hospital, Fulham, and as Assistant House Surgeon at the Metropolitan Hospital, London. A few personal items, largely testimonials and photographs supplement these, together with medical papers by Falkener. Falkener's later career as a general practitioner at Icart, Guernsey, is represented by a collection of his prescriptions.

The papers are very extensive though there are some lacunae, probably attributable to Chain's many changes of workplace. The early biographical period is sparsely documented, there are sporadic gaps in the correspondence files, and there is no original documentation of the penicillin research at Oxford (although there are many historical accounts and much correspondence about the history of penicillin). The surviving biographical material provides documentation of the arrangements for Chain to live and work in Britain, later honours and awards and his musical interests, and family correspondence, photographs and press-cuttings. There are very substantial records of his later career at the Istituto Superiore di Sanità and Imperial College, London, including his continuing contributions to biochemical problems such as carbohydrate metabolism, ergot alkaloids, edible proteins and aeration studies. The Imperial College material also contains records of the creation, administration, finance and architectural design of the Biochemistry Department, and developments in the Department after Chain's statutory retirement in 1973. Additional information about Chain's research is available in the documentation of his very extensive consultancy agreements and collaborative work with industrial firms such as Astra, Beechams and Rank Hovis McDougall, and records relating to government, grant-giving and charitable bodies such as the British Heart Foundation, Cancer Research Campaign and Medical Research Council which contributed to the funding of his research. There is much material on Chain's lectures, addresses and broadcasts, and on his extensive travel on visits and conferences, which includes a substantial number of unpublished talks.

An exceptional feature of the Chain papers is the documentation of the large number of Israel and Jewish organisations with which he was associated, especially the Weizmann Institute of Science, where he was a governor for many years and had at one time considered taking up an appointment.

Sargant was an outspoken supporter and practitioner of what he termed the 'practical rather than philosophical approaches' to the treatment of mental illness, pioneering and publicising various physical treatments and vociferously opposing the use of psychoanalytic techniques. The majority of the collection consists of his writings, both published and unpublished, supplemented by a small quantity of correspondence and other material. In addition, the collection contains clinical records for about 500 cases from Sutton Emergency Hospital in the 1940s. As well as covering clinical subjects (in Sections D, E, and F) and Sargant's views on the practice of psychiatry in general (Section B), the collection also contains material relating to his interest in the related issues of religious conversion and brainwashing (Section G).

Papers of the British Medical Association compring files [1915-1960], from the following subject series: Medico-Political, Science, Groups, Ethics, Public Health, Hospitals, Organisation. Also incomplete set of copy minutes of Council, Committees and of the Annual Representatives' Meetings and Special Representatives' Meetings, [1907-1982].

Notes of Charles Barbeyrac's practice taken chiefly by his students. Some case histories are included in MS.7126.

Papers of Jean Nicholas Marjolin and his son René Marjolin, 1849-1894, including notes of Jean Nicolas Marjolin's lectures, by a medical student; letters from René Marjolin to his friend Edmond Dascols relating mainly to personal affairs, and the health of the Dascols family (with advice on cholera and other maladies) and letters from Paris at the time of the siege and the Commune, 1870-1871, when René Marjolin was active in treating the wounded prior to his arrest as a Bonapartist agent.

Book of prescriptions by various hands. The date 1914 is found on p. 10, and 1937 on p. 59. Prices are added to some of the entries. Produced in London.

Albums containing medical prescriptions written for members of Lord Kenyon's family. The prescriptions were written mainly by Sir Charles Herbert (d. 1855), and Arthur Noverre (1816-1878), FRCS.

Lecture notes and other papers of Sir Hermann Gollancz including notes from lectures on the philosophy of mind, given by George Croom Robertson (1842-1892) at University College, London; notes from lectures at University College, London, comprising lectures on applied mathematics by William Kingdom Clifford (1845-1879), and on physics by George Carey Foster. Also included are notes on the history of the Jews in Sicily; notes on aspects of Jewish religion and theology. Signature inside the front cover, 'H Gollancz, Jews' College' and medical prescriptions written for Sir Hermann Gollancz, and miscellaneous medical ephemera.

Papers of Professor Leslie Harold Collier including laboratory notebook re heat-stable smallpox vaccine, 1949, and 8 files of correspondence and papers re trachoma research, 1944-1971.

'Report of Special Operational Store Tyburn, Jan-Nov 1945', by Marinus van den Ende (1912-1957), bacteriologist; and notes and photographs by Dr Helène E. Bargmann, PhD, FRZS, ATS (1897-1987), biologist.

Records of Fulham Road Pharmacy, Chelsea, including prescription books, 1887-1989, controlled drugs and poisons books, 1939-1978 and loose prescriptions 1953-1980.

Papers of William Gelder including letters from Gelder to his parents in Wakefield, while a dispensing and visiting assistant to [R Lucie] Reed, surgeon, at Whitechapel Road, London, Mar-Nov 1832, and while in Edinburgh in the employ of Mr Cope, a wholesale, retail and manufacturing chemist and druggist, Mar-Aug 1834. Notebook begun by Gelder in Edinburgh in 1834, and continued on a tour through Lancashire, the Isle of Man, Ireland and Wales in 1835, and in trade in Yorkshire, 1836-1837. Containing verses, commonplaces, orders for medicines and other goods, and miscellaneous notes. Signature inside front cover, 'William Gelder, Apothecaries' Hall, Edinbro, 1834.' On the rear end-papers is a coloured engraving of Apothecaries Hall.

Prescription and invoice books of James Brocklehurst, chemist, 1835-1873.

Accounts for medicines supplied by Hallifax as Royal Apothecary to George, Prince of Wales (afterwards King George IV) and to the Prince of Wales' household. Both sets of accounts bear the signatures (on examination and approval) of Sir Richard Jebb, physician to the Prince, and Charles Fitzroy, 1st Baron Southampton, groom of the stole to the Prince. With signatures (on receipt of payment) of Robert Hallifax.

Prescription books of T Burden & Co.

Letters and papers of James Ormiston McWilliam, 1839-1862. The letters to McWilliam show the interest generated by his investigations into contagious diseases such as yellow fever, and his subsequent official reports. Other contemporary naval issues form a major part of the subject-matter, especially the working conditions and status of assistant surgeons, on whose behalf McWilliam campaigned.

Papers of Charles, Joseph and Jean Sédillot, medics, 1790-1875.

Minute books of the Society of Apothecaries, 1629-1675.

Papers of Ann Gwendolen Dally and Peter John Dally, 1953-1991 including patient and other records of their joint private practice, plus Dr Ann Dally's correspondence with General Medical Council and writings relating to drug addiction.

Papers connected with James Randal Hutchinson and William Henry Bradley's work in the Ministry of Health, 1890-1959 with some retrospective material, and small groups of papers of Sir Weldon Dalrymple-Champneys (on Brucellosis) and Dr J Allison Glover.

Notes and photographs of experiment by John Edward French and Arthur Gordon Sanders at the Sir William Dunn School of Pathology, Oxford, concerning effect of cholesterol feeding on the liver, 1956.

Croadsell collection comprising pharmacy prescription books and ledgers, 1923-1951.

Papers of Jesse Robert Garrood, 1930-1951, including 3 day books of his general practice, 1930-1933, 1931-1937 and 1948-1951, and Vaccinator's Register, Jan 1947-Mar 1948.

Material relating to the use of nitrus oxide, chloroform and ether, mostly notes, including some on an operation carried out on Napolean III, and notes for lectures given by Clover. There is some personal material relating to Clover's education, including some family correspondence.

Ledgers recording accounts for medical treatment and drugs dispensed, 1744-1799. Patients included, as well as private individuals, the Oxfordshire and Herefordshire militias, the poor of various parishes, and the local bridewell. On the front covers are annotations by Dr B E A Batt and his father Dr C D Batt, including the names of Edward Batt (1741-1797), surgeon and apothecary, and Augustine William Batt (1774-1847), MRCS Eng. Both practised in Witney.

Notebooks kept by three generations of the Carr family, William Carr (b 1715), of Settle, Yorks.; William Carr (1745-1821), apothecary to the Leeds Infirmary, 1774-1781, surgeon apothecary at Elland, Yorks., 1784, and later at Gomersal; and William Carr (1785-1861), general practitioner, of Gomersal.

Papers of Frederick Gardiner comprising short papers on dermatological subjects, and material for the third edition of Gardiner's Handbook of Skin Diseases.

Personal papers and correspondence of John Coakley Lettsom, 1766-1812, including medical papers and pamphlets by Lettsom, newspaper cuttings relating to him, or subjects that interested him. Letters from various correspondents, mainly from the medical profession. The papers reflect his primary interests in 'Quacks and Quackery', clinical medicine, pathology, materia medica, variolation and vaccination. Many relate to the business of the Medical Society of London, of which Lettsom was President. There is also a fragment of an autobiography of his life as a as a student, MS.3245.

Holograph manuscripts of publications by Joseph von Schneller, notes, and some material by other persons collected by von Schneller, 1837-1885.

The bulk of the papers are reports and talks reflecting Sir Weldon Dalrymple-Champneys' interests as a physician and wide range of duties as Deputy Chief Medical Officer of Health at the Ministry of Health. The subject files (section H) contain details, including some manuscript diaries, of work in which he was particularly closely involved, such as snake venom and brucellosis. Texts of talks and broadcasts, some extracted from those subject files, are brought together in section F. Section D includes personal letters from distinguished colleagues. Sections A-C include mementos of Sir Weldon's father, Sir Francis Henry Champneys (1848-1930), a pioneer of modern midwifery who was Physician-Accoucheur at St. Bartholomew's Hospital in London (1891-1913).

Carbon copies of Martha Marquardt's transcripts of Paul Ehrlich's copybooks, 1898-1915, made by her during the early 1950s. There are 6 series, representing both copies of letters sent by him, and notebooks. There are not complete sets of transcripts for all of these: in some cases the originals themselves appear to no longer exist. Users should be aware that, according to a letter from Dr E A Underwood, Director of the Wellcome Historical Medical Museum, to Gunther Schwerin, 25 Mar 1963 (WA/HMM/CO/Eau/13), there are some misreadings by Marquardt of scientific terms in the originals, as, although she was capable of deciphering Ehrlich's writing, she was not herself a scientist. The originals are now in Boxes 4-22, 27-27A, 28-28A, 29-36 in the Paul Ehrlich Collection at the Rockefeller Archives Centre, and another set of transcripts in Boxes 80-86 there.

Papers of William Edward Van Heyningen, 1947-1978, including laboratory notebooks (bacterial toxins, dysentery, tetanus), 1947-1961; correspondence on cholera, 1967-1978, and tetanus, 1956-1974; miscellaneous reports and publications (mainly cholera).

Papers of the Lister Institute of Preventive Medicine (LIPM), 1886-1986, comprising minutes, 1886-1982; annual reports, 1895-1986; records relating to the origins and establishment of LIPM, 1889-1898; records of LIPMs links and amalgamations with other bodies, 1886-1898; records relating to vivisection, 1889-1899; Lord Lister's correspondence, 1893-1912; J L Pattison's correspondence, 1898-1903 and 1914; records relating to LIPMs organisation and administration, 1896-1949; production and distribution records for serum and vaccine lymph, 1894-1950; records relating to research projects, 1891-c1940s; records relating to LIPMs relations with outside bodies and individuals, 1889-1975; records relating to properties of LIPM; historical material; biographical material; miscellaneous papers; pamphlets relating to LIPM and associated bodies; pamphlets relating to other institutions; photographs; photocopies of letters from Lord Lister to Dr G Dean; and an index of correspondents.

Papers of Thomas Newborn Robert Morson, (1800-1874), and Thomas Morson and Son Ltd, comprising T N R Morsons's Parisian journal, 1818; personal and professional papers, 1834-1871; personal, family and other correspondence, 1826-1957, including correspondence with Jacob Bell (1810-1859) founder of the Pharmaceutical Society, and Charles Dickens, novelist; legal papers and agreements, 1879-1963; business correspondence and papers, 1866-1970; accounts and other financial records, 1868-1979; recipes, production and sampling records, c 1848-1957; advertising records, 1821-c 1970; sales records, 1887-1955, including an order book containing a record of orders placed by the Secretary of State for India, 1887-1947; company scrapbooks and press cuttings, c 1906-1950; records of premises, c 1870-1965, including a series of photographs by Henri Claudet, of the works at Hornsey Rise; staff records, 1878-1971; historical publications and company history, 1916-1988; portrait photographs, c1850-1938 including T N R Morson and members of his family, and contemporary scientists, authors and others including Thomas Bell FRS, William Thomas Brande, Thomas Graham, Michael Faraday, and Heinrich Rose; other publications, 1751-1957; and the historical research papers of Anthony Morson.

The archive spans Browne's career from school onwards, but the core series of records focus on his work as a medical missionary at the BMS hospital in Yakusu, Belgian Congo (now the Democratic Republic of Congo). Section B comprises records for the period 1938-1958, including registers of leprosy sufferers, case records and photograph albums documenting various symptoms. Section K contains further photographs (mainly clinical) for the period 1938-1977, the most important series of which dates from Browne's time at the Baptist Mission Hospital and comprises over 900 negatives and prints together with supporting documentation, 1954-1958.

Section C contains a small number of files compiled by Browne during his research into leprosy, yaws, onchocerciasis and ainhum, 1946-1983. Particularly notable are the files on the anti-leprosy drug B663 (now known as clofazimine), into the use of which Browne conducted pioneering studies whilst director of the Leprosy Research Unit, Uzuakoli, Eastern Nigeria, 1959-1966.The remaining records comprise personal and biographical material, 1923-1985 (section A); general subject files containing correspondence, reprints etc. on a wide variety of topics, 1948-1986 (section D); writings by Browne, 1935-1985 (section E); records of Browne's involvement with the International Leprosy Association, 1909-1985 (section F) and various other organisations, 1959-1986 (section G); records on foreign visits, 1965-1985 (section H); and a few files on religious matters, 1959-1984 (section J).

Recipe and account book with ownership inscription of Thomas Brigstocke Humphreys, Portmadoc, 1859. The book has later been used to accommodate newspaper cuttings (including several relating to members of the Humphreys and Brigstocke families, among them H. Humphreys of Aberystwyth, also a chemist, and various Humphreys in Llanelli) and ephemera. The latter relate to a wide variety of chemists' firms, chiefly in London; these include Corbyn and Co. (see MSS. 5435-5460).

Papers of Sir William Drummond Macdonald Paton, 1930-1993, chiefly comprising papers relating to his main research interests, namely underwater physiology, histamine, synaptic transmission, drug dependence, anaesthetic mechanisms, allergy electron microscopy and the history of science, particularly medical science. The collection also includes correspondence, research papers and laboratory notebooks, and papers relating to the committee work that occupied his energies. Papers from Paton's time as both a Rhodes Trustee and a Wellcome Trustee provide further evidence of the extent of his commitments in committee.

Papers relating to Paton's Chairmanship of the Research Defence Committee (1972-77) are particularly extensive and reveal the social and political pressures of the period, the passionate challenges of the anti-vivisection lobby, as well as Paton's personal commitment to a socially responsible use of animals in scientific experimentation. Papers relating to Man and Mouse: Animals in Medical Research (1984), in which Paton set out his fundamental position on animal experimentation, provide further material on this topic.

Another field of interest in which Paton expended considerable energy was that of drug dependence, particularly the pharmacological action of cannabis. Through work in laboratory and committees, and through the media and many speaking engagements, he campaigned strenuously to warn of what he judged to be the deleterious effects of cannabis, and forged campaign alliances with American colleagues who shared his concerns.

Throughout his career, Paton maintained strong links with the Royal Navy, acting as scientific adviser and consultant on deep diving and underwater physiology. This strand of his work was of enduring interest: Paton's work on the physiological properties of gases at high pressure led directly to the development of the deep-diving breathing mixture known as 'Tri-Mix', in which nitrogen is added to helium and oxygen. Paton took great pleasure in the Royal Navy achieving, in 1980, the world's deepest dive (see D/2/14).

Harrods Pharmacy Department registers of prescriptions dispensed daily, Jul 1935-Jan 1977. There are gaps in the sequence between July 1936 and September 1938 and between December 1943 and April 1946, where the relevant registers were found to be missing on transfer to the Wellcome Archive.

Papers on a development by Henri Spahlinger of a controversial vaccine treatment for tuberculosis, 1909-1929, and press-cuttings relating to public reaction to his claims 1932-1939.

Reports and correspondence relating to the development of the drug Balsalazide, for treatment of people suffering from ulcerative colitis, 1979-1991.

Prescription books, ledgers, cash books, etc, of Nicholson and predecessor firms, 1893-1963.

This small but important collection is concerned with the research and development of penicillin. Heatley's laboratory notebooks (A.1-3), October 1939-June 1941, and sketches and diagrams of apparatus, 1941 (C. 1-5) form the core of the collection. The famous experiment of 25 May 1941 on the 'Curative Effect of Penicillin' on mice is recorded in notebook A.2. There are also diary entries, narratives and explanatory notes, some prepared by Heatley expressly for the collection. The correspondence and reports exchanged between Heatley and Florey (section D.) is a set of photocopies, included to provide a complete account of the collaboration between the two on the penicillin project.

Prescription books from 16 Jun 1745-25 Dec 1747 and 12 Nov1768-30 Nov 1769. The second volume contains entries for medicines prescribed for the Duke of Wellington, who was born at Mornington House, 24 Upper Merrion Street, Dublin on April 29, 1769. On the outside of the upper cover is a slip dated 17/8/1899, which states that the original earliest entry in the volume for 30 April 1769 has been cut out and framed for display in the shop at 49 Dawson Street, Dublin: another dated July 2 has also been cut out and 'given to Fielding Ould [?] Esqre' (i.e. Sir Fielding Ould, Dublin obstetrician, 1710-89). This manuscript still contains entries for the Countess of Mornington 2 May; 'Lord Mornington's young child', 4 May; 'The Countess of Mornington, the young child' 16 May; 'Lady Mornington, Master Frank Wesley, Young son', 25 May; 'The Hon. Master Arthur Wesley', 17 June. This last entry is also found for 2 July, 3 July, 6 July. According to the notice in the Oxford Dictionary of National Biography, Wellington used the form 'Wesley' for his name until 1798. Produced in Dublin.

These papers comprise the manuscript collection of F[rederick] Bacon Frank (1827-1911). They include a medieval medical miscellany (MS.550), material by or relating to the 17th century Yorkshire physician Nathaniel Johnston (MSS.3083-3086 and 6080), and some Bacon family administrative documents (MS.6079). One item relating to Nathaniel Johnston that did not form part of the Bacon Frank collection has been catalogued with it for convenience (MS.3086).

Records and collection of manuscripts of the Hunterian Society, 1676-1989. The manuscript collection includes extensive letters and papers relating to the Hunter and Baillie families.

Prescription books, account books, ledgers, and note book of chemists R Woollatt and J Boyd, 1880-1944.

Personalia and memorabilia of Walter Ernest Dixon and G Norman Myers, 1865-1949; files relating to their pharmacological research (digitalis, morphine substitutes, coramine, etc) and teaching and glass lantern slides, some of Dixon and colleagues, mostly relating to research.

Papers of Herbert Davies Chalke, 1924-[1980] including lecture notes, papers and publications, including re alcoholism, TB, care of the elderly, and food safety. Also papers re service with RAMC in North Africa.