Identity area
Reference code
Title
Date(s)
- 1938-1984 (Creation)
Level of description
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4 boxes
Context area
Name of creator
Biographical history
Born 1908. The core of the collection are reprints on biological catalysts, cellular respiration and enzymes, published during the period 1925-1960 by David Keilin, ScD,FRS (1887-1963) and his associates at the Molteno Institute of Biology and Parasitology. Professor Mann worked with him from 1935-1942 on collaborated research into enzymology and cellular metabolism. 'Together we succeeded in discovering the first enzyme-substrate reaction by demonstrating that peroxidase, the methaemoglobin-like plant enzyme, forms two distinct reaction products with hydrogen peroxide. We identified copper in the enzymes of polyphenol oxidase from mushrooms and laccase from the lacquer tree. We succeeded in isolating and crystallizing haemocuprein, the first copper-protein from mammalian blood-corpuscles, and we were the first to discover zinc in an enzyme, namely that of carbonic anhydrase from mallian blood.' Some of his subsequent research was carried out at the Molteno Institute: 1942-1944, metabolism of mould fungi; after 1944, metabolism of mammalian semen, discovery of fructose in semen and many other studies on the biochemistry of spermatozoa, male accessory secretions and male reproductive organs; died 1993.
Repository
Archival history
GB 0120 GC/64 1938-1984 Collection 4 boxes Mann , Thaddeus Robert Rudolph , 1908-1993 , doctor
Born 1908. The core of the collection are reprints on biological catalysts, cellular respiration and enzymes, published during the period 1925-1960 by David Keilin, ScD,FRS (1887-1963) and his associates at the Molteno Institute of Biology and Parasitology. Professor Mann worked with him from 1935-1942 on collaborated research into enzymology and cellular metabolism. 'Together we succeeded in discovering the first enzyme-substrate reaction by demonstrating that peroxidase, the methaemoglobin-like plant enzyme, forms two distinct reaction products with hydrogen peroxide. We identified copper in the enzymes of polyphenol oxidase from mushrooms and laccase from the lacquer tree. We succeeded in isolating and crystallizing haemocuprein, the first copper-protein from mammalian blood-corpuscles, and we were the first to discover zinc in an enzyme, namely that of carbonic anhydrase from mallian blood.' Some of his subsequent research was carried out at the Molteno Institute: 1942-1944, metabolism of mould fungi; after 1944, metabolism of mammalian semen, discovery of fructose in semen and many other studies on the biochemistry of spermatozoa, male accessory secretions and male reproductive organs; died 1993.
Professor Mann gave his reprints and additional papers to the Contemporary Medical Archives Centre in July 1984.
Papers of Thaddeus Robert Rudolph Mann, 1938-1984; comprising biographical and bibliographical material, notebooks and reprints on enzyme research, 1938-1954; photographs of the Molteno Institute of Biology and Parasitology, Cambridge, 1925-1960.
4 series: notebooks, bibliography, reprints and publications.
Open. The papers are available subject to the usual conditions of access to Archives and Manuscripts material, after the completion of a Reader's Undertaking.
Photocopies/photographs/microfilm are supplied for private research only at the Archivist's discretion. Please note that material may be unsuitable for copying on conservation grounds, and that photographs cannot be photocopied in any circumstances. Readers are restricted to 100 photocopies in twelve months. Researchers who wish to publish material must seek copyright permission from the copyright owner.
English
Wellcome Library online catalogue.
In 1991 additional biographical material and twelve laboratory notebooks recording research in physiology and biochemistry of reproduction, 1947-1976, were given to Cambridge University Library via the National Cataloguing Unit for the Archives of Contemporary Scientists (NCUACS catalogue no 30/6/91 6 pp).
Entry compiled from Wellcome Library online catalogue by Barbara Ball.
Compiled in compliance with General International Standard Archival Description, ISAD(G), second edition, 2000; National Council on Archives Rules for the Construction of Personal Place and Corporate Names 1997.
September 2008 Mann , Thaddeus Robert Rudolph , 1908-1993 , doctor Medical research Science Physiology Biochemistry Enzymes Biochemicals
Immediate source of acquisition or transfer
Professor Mann gave his reprints and additional papers to the Contemporary Medical Archives Centre in July 1984.
Content and structure area
Scope and content
Papers of Thaddeus Robert Rudolph Mann, 1938-1984; comprising biographical and bibliographical material, notebooks and reprints on enzyme research, 1938-1954; photographs of the Molteno Institute of Biology and Parasitology, Cambridge, 1925-1960.
Appraisal, destruction and scheduling
Accruals
System of arrangement
4 series: notebooks, bibliography, reprints and publications.
Conditions of access and use area
Conditions governing access
Open. The papers are available subject to the usual conditions of access to Archives and Manuscripts material, after the completion of a Reader's Undertaking.
Conditions governing reproduction
Photocopies/photographs/microfilm are supplied for private research only at the Archivist's discretion. Please note that material may be unsuitable for copying on conservation grounds, and that photographs cannot be photocopied in any circumstances. Readers are restricted to 100 photocopies in twelve months. Researchers who wish to publish material must seek copyright permission from the copyright owner.
Language of material
- English
Script of material
- Latin
Language and script notes
English
Physical characteristics and technical requirements
Finding aids
Wellcome Library online catalogue.
Allied materials area
Existence and location of originals
Existence and location of copies
Related units of description
In 1991 additional biographical material and twelve laboratory notebooks recording research in physiology and biochemistry of reproduction, 1947-1976, were given to Cambridge University Library via the National Cataloguing Unit for the Archives of Contemporary Scientists (NCUACS catalogue no 30/6/91 6 pp).
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Compiled in compliance with General International Standard Archival Description, ISAD(G), second edition, 2000; National Council on Archives Rules for the Construction of Personal Place and Corporate Names 1997.
Status
Level of detail
Dates of creation revision deletion
Language(s)
- English