Collection GB 0120 GC/64 - Mann, Thaddeus Robert Rudolph (1908-1993)

Identity area

Reference code

GB 0120 GC/64

Title

Mann, Thaddeus Robert Rudolph (1908-1993)

Date(s)

  • 1938-1984 (Creation)

Level of description

Collection

Extent and medium

4 boxes

Context area

Name of creator

Biographical history

Born 1908. The core of the collection are reprints on biological catalysts, cellular respiration and enzymes, published during the period 1925-1960 by David Keilin, ScD,FRS (1887-1963) and his associates at the Molteno Institute of Biology and Parasitology. Professor Mann worked with him from 1935-1942 on collaborated research into enzymology and cellular metabolism. 'Together we succeeded in discovering the first enzyme-substrate reaction by demonstrating that peroxidase, the methaemoglobin-like plant enzyme, forms two distinct reaction products with hydrogen peroxide. We identified copper in the enzymes of polyphenol oxidase from mushrooms and laccase from the lacquer tree. We succeeded in isolating and crystallizing haemocuprein, the first copper-protein from mammalian blood-corpuscles, and we were the first to discover zinc in an enzyme, namely that of carbonic anhydrase from mallian blood.' Some of his subsequent research was carried out at the Molteno Institute: 1942-1944, metabolism of mould fungi; after 1944, metabolism of mammalian semen, discovery of fructose in semen and many other studies on the biochemistry of spermatozoa, male accessory secretions and male reproductive organs; died 1993.

Archival history

GB 0120 GC/64 1938-1984 Collection 4 boxes Mann , Thaddeus Robert Rudolph , 1908-1993 , doctor

Born 1908. The core of the collection are reprints on biological catalysts, cellular respiration and enzymes, published during the period 1925-1960 by David Keilin, ScD,FRS (1887-1963) and his associates at the Molteno Institute of Biology and Parasitology. Professor Mann worked with him from 1935-1942 on collaborated research into enzymology and cellular metabolism. 'Together we succeeded in discovering the first enzyme-substrate reaction by demonstrating that peroxidase, the methaemoglobin-like plant enzyme, forms two distinct reaction products with hydrogen peroxide. We identified copper in the enzymes of polyphenol oxidase from mushrooms and laccase from the lacquer tree. We succeeded in isolating and crystallizing haemocuprein, the first copper-protein from mammalian blood-corpuscles, and we were the first to discover zinc in an enzyme, namely that of carbonic anhydrase from mallian blood.' Some of his subsequent research was carried out at the Molteno Institute: 1942-1944, metabolism of mould fungi; after 1944, metabolism of mammalian semen, discovery of fructose in semen and many other studies on the biochemistry of spermatozoa, male accessory secretions and male reproductive organs; died 1993.

Professor Mann gave his reprints and additional papers to the Contemporary Medical Archives Centre in July 1984.

Papers of Thaddeus Robert Rudolph Mann, 1938-1984; comprising biographical and bibliographical material, notebooks and reprints on enzyme research, 1938-1954; photographs of the Molteno Institute of Biology and Parasitology, Cambridge, 1925-1960.

4 series: notebooks, bibliography, reprints and publications.

Open. The papers are available subject to the usual conditions of access to Archives and Manuscripts material, after the completion of a Reader's Undertaking.

Photocopies/photographs/microfilm are supplied for private research only at the Archivist's discretion. Please note that material may be unsuitable for copying on conservation grounds, and that photographs cannot be photocopied in any circumstances. Readers are restricted to 100 photocopies in twelve months. Researchers who wish to publish material must seek copyright permission from the copyright owner.

English

Wellcome Library online catalogue.

In 1991 additional biographical material and twelve laboratory notebooks recording research in physiology and biochemistry of reproduction, 1947-1976, were given to Cambridge University Library via the National Cataloguing Unit for the Archives of Contemporary Scientists (NCUACS catalogue no 30/6/91 6 pp).

Entry compiled from Wellcome Library online catalogue by Barbara Ball.

Compiled in compliance with General International Standard Archival Description, ISAD(G), second edition, 2000; National Council on Archives Rules for the Construction of Personal Place and Corporate Names 1997.

September 2008 Mann , Thaddeus Robert Rudolph , 1908-1993 , doctor Medical research Science Physiology Biochemistry Enzymes Biochemicals

Immediate source of acquisition or transfer

Professor Mann gave his reprints and additional papers to the Contemporary Medical Archives Centre in July 1984.

Content and structure area

Scope and content

Papers of Thaddeus Robert Rudolph Mann, 1938-1984; comprising biographical and bibliographical material, notebooks and reprints on enzyme research, 1938-1954; photographs of the Molteno Institute of Biology and Parasitology, Cambridge, 1925-1960.

Appraisal, destruction and scheduling

Accruals

System of arrangement

4 series: notebooks, bibliography, reprints and publications.

Conditions of access and use area

Conditions governing access

Open. The papers are available subject to the usual conditions of access to Archives and Manuscripts material, after the completion of a Reader's Undertaking.

Conditions governing reproduction

Photocopies/photographs/microfilm are supplied for private research only at the Archivist's discretion. Please note that material may be unsuitable for copying on conservation grounds, and that photographs cannot be photocopied in any circumstances. Readers are restricted to 100 photocopies in twelve months. Researchers who wish to publish material must seek copyright permission from the copyright owner.

Language of material

  • English

Script of material

  • Latin

Language and script notes

English

Physical characteristics and technical requirements

Finding aids

Wellcome Library online catalogue.

Allied materials area

Existence and location of originals

Existence and location of copies

Related units of description

In 1991 additional biographical material and twelve laboratory notebooks recording research in physiology and biochemistry of reproduction, 1947-1976, were given to Cambridge University Library via the National Cataloguing Unit for the Archives of Contemporary Scientists (NCUACS catalogue no 30/6/91 6 pp).

Related descriptions

Notes area

Alternative identifier(s)

Access points

Place access points

Name access points

Genre access points

Description control area

Description identifier

Institution identifier

Wellcome Library

Rules and/or conventions used

Compiled in compliance with General International Standard Archival Description, ISAD(G), second edition, 2000; National Council on Archives Rules for the Construction of Personal Place and Corporate Names 1997.

Status

Level of detail

Dates of creation revision deletion

Language(s)

  • English

Script(s)

    Sources

    Accession area