Zone d'identification
Cote
Titre
Date(s)
- 1938-1984 (Création/Production)
Niveau de description
Étendue matérielle et support
4 boxes
Zone du contexte
Nom du producteur
Notice biographique
Born 1908. The core of the collection are reprints on biological catalysts, cellular respiration and enzymes, published during the period 1925-1960 by David Keilin, ScD,FRS (1887-1963) and his associates at the Molteno Institute of Biology and Parasitology. Professor Mann worked with him from 1935-1942 on collaborated research into enzymology and cellular metabolism. 'Together we succeeded in discovering the first enzyme-substrate reaction by demonstrating that peroxidase, the methaemoglobin-like plant enzyme, forms two distinct reaction products with hydrogen peroxide. We identified copper in the enzymes of polyphenol oxidase from mushrooms and laccase from the lacquer tree. We succeeded in isolating and crystallizing haemocuprein, the first copper-protein from mammalian blood-corpuscles, and we were the first to discover zinc in an enzyme, namely that of carbonic anhydrase from mallian blood.' Some of his subsequent research was carried out at the Molteno Institute: 1942-1944, metabolism of mould fungi; after 1944, metabolism of mammalian semen, discovery of fructose in semen and many other studies on the biochemistry of spermatozoa, male accessory secretions and male reproductive organs; died 1993.
Dépôt
Histoire archivistique
GB 0120 GC/64 1938-1984 Collection 4 boxes Mann , Thaddeus Robert Rudolph , 1908-1993 , doctor
Born 1908. The core of the collection are reprints on biological catalysts, cellular respiration and enzymes, published during the period 1925-1960 by David Keilin, ScD,FRS (1887-1963) and his associates at the Molteno Institute of Biology and Parasitology. Professor Mann worked with him from 1935-1942 on collaborated research into enzymology and cellular metabolism. 'Together we succeeded in discovering the first enzyme-substrate reaction by demonstrating that peroxidase, the methaemoglobin-like plant enzyme, forms two distinct reaction products with hydrogen peroxide. We identified copper in the enzymes of polyphenol oxidase from mushrooms and laccase from the lacquer tree. We succeeded in isolating and crystallizing haemocuprein, the first copper-protein from mammalian blood-corpuscles, and we were the first to discover zinc in an enzyme, namely that of carbonic anhydrase from mallian blood.' Some of his subsequent research was carried out at the Molteno Institute: 1942-1944, metabolism of mould fungi; after 1944, metabolism of mammalian semen, discovery of fructose in semen and many other studies on the biochemistry of spermatozoa, male accessory secretions and male reproductive organs; died 1993.
Professor Mann gave his reprints and additional papers to the Contemporary Medical Archives Centre in July 1984.
Papers of Thaddeus Robert Rudolph Mann, 1938-1984; comprising biographical and bibliographical material, notebooks and reprints on enzyme research, 1938-1954; photographs of the Molteno Institute of Biology and Parasitology, Cambridge, 1925-1960.
4 series: notebooks, bibliography, reprints and publications.
Open. The papers are available subject to the usual conditions of access to Archives and Manuscripts material, after the completion of a Reader's Undertaking.
Photocopies/photographs/microfilm are supplied for private research only at the Archivist's discretion. Please note that material may be unsuitable for copying on conservation grounds, and that photographs cannot be photocopied in any circumstances. Readers are restricted to 100 photocopies in twelve months. Researchers who wish to publish material must seek copyright permission from the copyright owner.
English
Wellcome Library online catalogue.
In 1991 additional biographical material and twelve laboratory notebooks recording research in physiology and biochemistry of reproduction, 1947-1976, were given to Cambridge University Library via the National Cataloguing Unit for the Archives of Contemporary Scientists (NCUACS catalogue no 30/6/91 6 pp).
Entry compiled from Wellcome Library online catalogue by Barbara Ball.
Compiled in compliance with General International Standard Archival Description, ISAD(G), second edition, 2000; National Council on Archives Rules for the Construction of Personal Place and Corporate Names 1997.
September 2008 Mann , Thaddeus Robert Rudolph , 1908-1993 , doctor Medical research Science Physiology Biochemistry Enzymes Biochemicals
Source immédiate d'acquisition ou de transfert
Professor Mann gave his reprints and additional papers to the Contemporary Medical Archives Centre in July 1984.
Zone du contenu et de la structure
Portée et contenu
Papers of Thaddeus Robert Rudolph Mann, 1938-1984; comprising biographical and bibliographical material, notebooks and reprints on enzyme research, 1938-1954; photographs of the Molteno Institute of Biology and Parasitology, Cambridge, 1925-1960.
Évaluation, élimination et calendrier de conservation
Accroissements
Mode de classement
4 series: notebooks, bibliography, reprints and publications.
Zone des conditions d'accès et d'utilisation
Conditions d'accès
Open. The papers are available subject to the usual conditions of access to Archives and Manuscripts material, after the completion of a Reader's Undertaking.
Conditions de reproduction
Photocopies/photographs/microfilm are supplied for private research only at the Archivist's discretion. Please note that material may be unsuitable for copying on conservation grounds, and that photographs cannot be photocopied in any circumstances. Readers are restricted to 100 photocopies in twelve months. Researchers who wish to publish material must seek copyright permission from the copyright owner.
Langue des documents
- anglais
Écriture des documents
- latin
Notes de langue et graphie
English
Caractéristiques matérielle et contraintes techniques
Instruments de recherche
Wellcome Library online catalogue.
Zone des sources complémentaires
Existence et lieu de conservation des originaux
Existence et lieu de conservation des copies
Unités de description associées
In 1991 additional biographical material and twelve laboratory notebooks recording research in physiology and biochemistry of reproduction, 1947-1976, were given to Cambridge University Library via the National Cataloguing Unit for the Archives of Contemporary Scientists (NCUACS catalogue no 30/6/91 6 pp).
Zone des notes
Identifiant(s) alternatif(s)
Mots-clés
Mots-clés - Sujets
Mots-clés - Lieux
Mots-clés - Noms
Mots-clés - Genre
Zone du contrôle de la description
Identifiant de la description
Identifiant du service d'archives
Règles et/ou conventions utilisées
Compiled in compliance with General International Standard Archival Description, ISAD(G), second edition, 2000; National Council on Archives Rules for the Construction of Personal Place and Corporate Names 1997.
Statut
Niveau de détail
Dates de production, de révision, de suppression
Langue(s)
- anglais