The vast majority of the material relates to Dent's research and clinical interests and falls into four main categories: correspondence files; files created around the publication of papers; lecture notes and symposium papers; and case/research notes. There are also smaller quantities dealing with other aspects of his career, such as the administration of UCH Metabolic Ward. The papers thus reflect most of Dent's scientific and clinical interests. This research is mainly represented by the abstracted documentation which he kept with drafts of his published papers (see section E.1) and also by correspondence about cases and clinical case notes (see section C.5). To a lesser degree they also illustrate the work at the laboratory bench which underpinned much of this research. For example, a file of unidentified paper chromatograms has been preserved (C.2/10) to illustrate one of Dent's methods of working, as described by his colleague, Heathcote, and quoted in the Biographical Memoirs of Fellows of the Royal Society, 1978: 'Paper chromatograms were not to be thrown away. They were filed and, since the colours faded, the outline of each spot was drawn in and the intensity of the colour was indicated by a number.' The way in which Dent compiled a large series of files around drafts of scientific papers also illustrates the importance of the published paper to him as a stage in the research process. An incomplete collection of reprints of Dent's published papers may be found in section E.2 of the collection.

Papers of Dame Harriette Chick: this collection represents a relatively limited record of Chick's long and active career. It is particularly strong on the period around her important work in Vienna, 1919-1921, and includes some material relating to other research on nutritional questions.

Papers of Ernest Basil Verney, 1922-1966, including experimental notes and notebooks, 1921-1966; also lecture notes, correspondence, reports, reprints and press cuttings.

Papers of Henry Foy and Athena Kondi, [1934-1990], comprising:

(A) records of haematological research into B vitamin deficiencies including records of serum tests, biopsies and post mortems on baboons, plus correspondence, reports and photographs, 1963-1977;

(B) surveys of anaemia and sickle cell anaemia in Mozambique, Kenya, Sudan, India, Mauritius, 1951-1974; survey of tropical sprue, 1962-1969;

(C) publications by Foy and Kondi, particularly on blackwater fever and anaemias in the tropics, 1935-c 1990;

(D) reference files of articles and reprints, mid 20th century-late 20th century;

(E) photographic material relating to research, and of the countries where Foy and Kondi worked, c 1934-1988

Papers of Sir Edward Mellanby, 1896-1974, notably relating to his research interests in vitamins, nutrition and deficiency and material on his activities subsequent to his retirement as an advisor on questions of research and medical administration. May Tweedy married Edward Mellanby in 1914 and collaborated in his research throughout the rest of their lives together, as well as working independently. It can thus be seen that it is not altogether easy to differentiate between the papers of this couple; for example in Section C of Sir Edward's papers are included a number of files and volumes relating to his wife's work as his associate, while her diaries in Section E contain details of her husband's activities as well as her own. Although Lady Mellanby was Sir Edward's collaborator throughout the course of his career, her papers are on the whole distinct from his and concentrate on her work in research into dentition and dental problems. They are therefore listed separately, and the list annotated at relevant points where there is an overlap. It is clear that these papers are not a complete record of the Mellanbys' careers. It is likely that following Sir Edward Mellanby's death, when the material underwent various moves, some items were lost. However, as for 16 years he was Secretary of the Medical Research Council, the record of those years is to be found among the files of the MRC, although details of the relevant files at the MRC are not yet available.

Records of the Physiological Society, including all the minute books from the foundation of the Society in 1876, the proposal books for candidates from 1888, correspondence, histories and photographs. The bulk of the material dates from after 1939.

Reports of Thomas Lauder Brunton's lectures on therapeutics and notes from a lecture on chloroform with three fragments of lectures on eye affections, on the effects of alcohol, and the effect of drugs on the brain given at St. Bartholomew's Hospital, 1892-[1895].

Incomplete set of notes of proceedings in anti-vivisection cause célèbre, the Lind-af-Hageby Libel Case, 1913. 19 items. Notes for the first two days of the case are missing.

Papers of J Hugh Baron including miscellaneous personal files, covering 1933-1994, including material relating to the Cogwheel report of 1967 on hospital medical administration; the 'Brown Dog' of University College London, a memorial erected by the Anti-vivisection League; and the journal Theoretical Surgery.

Includes:

• Richmond Labour Party Young Socialists agenda 1st October 1979 and report on the first meeting held at Star House on 13th September

• Advertisement for Zimbabwe National Demonstration Sunday, November 11, London. Produced by the Zimbabwe Emergency Campaign Committee

• Leaflet entitled 'Animals in Laboratories' by Animal Aid

• Membership application card for Labour Party Young Socialists (LPYS)

• Moscow News, No. 23, Sunday June 4, 1989.

Sir Henry Head's papers, 1891-1909, consist of his casebooks of patients with Herpes Zoster, with sketches and photographs, chiefly from Head's work at the London Hospital, 1891-1909, and his casebooks of patients with various diseases, with sketches and charts, from his work at the City of London Hospital for Diseases of the Heart and Lungs, Victoria Park, 1894.

Papers of Edward Percy Argyle, 1920-1935, comprising lecture notes compiled at the Army Veterinary School, Aldershot, 1920; correspondence and notes relating to the Imperial Bureau of Animal Health, 1934-1935; correspondence and notes relating to writing abstracts for the Veterinary Bulletin, for the Imperial Bureau of Animal Health; notes and memoranda for the article 'Lesions in Cases of Roaring' published in the Royal Army Veterinary Corps Journal, Aug 1933; letters, drawings and notes, including letters relating to the Buckstone Browne Research Farm at Downe; press cuttings relating to animals; letters relating to abstracts for Biological Abstracts, 1934; observations on horses and flies, 1933; letters from B Williamson at the Military Veterinary Hospital, Delhi, 1932; research notes; notes from lectures by Professor Monro at the Imperial College of Science, South Kensington, 1931; notes from Professor Munro's 2nd lecture series; notes and diary entries relating to experiments, investigations and publications, 1934-1935; notes for an article, 1934; correspondence and notes concerning research into the condition of roaring, 1933-1935; letter from John Beattie of the Hunterian Museum relating to research reports and Buckstone Browne Research Farm, 1934-1935; notes on Facial Palsy in horses; and photographs.

Extensive papers of Howard Walter Florey, Baron Florey, relating to almost every aspect of his career in science and public life. The scientific materials include a complete run of laboratory notebooks, 1924-1968, files on the work for which Florey is best known, penicillin and antibiotics, 1940-1962, together with papers, research notes and photographs on mucus secretion, traumatic shock and electron microscopy. Florey's writings are preserved in the form of drafts and proofs of published items, together with relevant correspondence. His correspondence indicates the depth of his involvement in the affairs of particular organisations, notably the Oxford University School of Pathology and the Royal Society. The work of Ethel Florey (née Hayter) and Margaret Augusta Florey (née Fremantle) is also present.

Records of the Battersea General Hospital, including Board of Management minutes, 1905-1955; Court of Governors minutes, 1946-1949; House Committee minutes, 1924-1971; Finance Committee minutes, 1932-1944; Appeals Committee minutes, 1938-1947; Medical Committee minutes, 1935-1971; copy of the Amended Memorandum and Articles of Association of the hospital, 1935; annual reports, 1943 - 1948; registers of managers of the Hospital, 1930-1947; bundle of legal papers relating to the case The Public Trustee v. The South London Hospital for Women and others (regarding the will of Constance Edith Guerrier on which the hospital were making a claim), 1926-1928 and papers and agreements concerning tenancies of hospital properties and services to hospital, 1915-1937.

Personal papers, letters, diary notes of First World War service, photographs, etc of Sir William Maddock Bayliss, 1877-1923. Also papers on EH Starling (1866-1927), physiologist, 1892-1927, which include letters of EA Sharpey-Shafer (1850-1935), physiologist, and AV Hill (1886-1977), physiologist; and letters of F Gowland Hopkins (1861-1947), biochemist, 1924-1936.

Minute books of the Council and Executive Committee of the Association for the Advancement of Medicine by Research, with inserted loose papers, from its formation in 1882 until 1892; minutes of the sub-committee on the Promotion of Research, 1882-1883, and letters to Stephen Paget, 1891-1892.

Manuscript volume titled Experiments Physiology 1776, 1776-1777, comprising notes of experiments carried out on dogs, cats, and on eggs. Including the names of persons present during the experiments. The script of the volume's title is in the handwriting of William Clift, however the text inside does not belong to Clift. In his catalogue of manuscripts, Victor Plarr suggests that the text is by a Scot experimenting at John Hunter's house.

William Keen collection, including correspondence, biographical material, notes, unpublished writings and photographs, including material on his opposition to the anti-vivisection movement, and the effects of lightning, c 1885-1929.

The collection includes material on several research projects undertaken by McCance and Widdowson, 1929-1993, as well as a small amount of personalia. There are notebooks recording the first research on analysis of foodstuffs carried out in the UK, started by McCance when at the Diabetes Department of King's College Hospital, after R D Lawrence asked him to analyse cooked foods. Widdowson joined him in 1933 and together they devised the separate methods for estimating different carbohydrates (glucose, fructose, sucrose, starch and dextrose). In 1940 their findings were published as Chemical composition of foods, the first of now regularly produced Standard Food Composition publications. There are notebooks and photographs of self-experimentation undertaken within the department, on salt-deficiency, conducted by McCance on himself, colleagues and medical students, involving not only a salt-free diet, but exposure to a hot air bath to sweat the salt out of the body, and also on absorption and excretion of iron. There is also his diary of the experimental study of rationing undertaken in 1939. There are 220 complete questionnaires from their survey of female colleagues and acquaintances for a study of physical and emotional periodicity in women, undertaken 1929-1930. There are experimental notebooks and files relating to research into body composition and development from 1944 onwards. This collection represents only a part of the diversity of research undertaken during the course of their long careers.

The archive consists of Mary Beatrice Crowle's annotated scrapbook entitled 'women pioneers'. This contains correspondence, photographs, leaflets, press cuttings, etc. It relates mainly to her family; Lady Astor, and the Conservative and Unionist Women's Franchise Association; Women Police; Australians in First World War; vivisection; natural healing. Below are given selected detailed item descriptions for visual material, the references indicate the page numbers.

Correspondence and papers of Sir Victor Horsley, 1883-1915, including notebook as Secretary to the Local Government Board inquiry into Pasteur's anti-rabies therapy, Apr-May 1886; papers and addresses by Horsley; letters to Horsley and miscellaneous papers, comprising papers relating to evidence given by Horsley to the Royal Commission on Vivisection, 1906-1907; an antivivisectionist postcard opposing Horsley as a parliamentary candidate (showing a banner with the head of a bulldog and the words 'Who said vivisection?'), Dec 1910; papers relating to Horsley's support for Christopher Addison, afterwards 1st Viscount Addison, at the Hoxton parliamentary election, January 1910; and a circular signed by Horsley as President of the National Temperance Federation, opposing the Army rum ration, 27 October 1914.

Research notes and drafts relating to two major works by Fraser-Harris. MSS.8109-8112, 8114-8120 and 8122 relate to the history of antisepsis and the essay 'Antiseptics before Lister: a historico-medical survey', which was the Prize Essay in the History of Medicine, University of Glasgow, 1932/3. MSS.8236-8255 and 8968-8989 relate to The History and Lore of Cymric Medicine, a proposed Wellcome Historical Medical Museum study that was never published. Wellcome and Fraser-Harris died close to one another and the momentum of the project was lost.

Papers of Sir Thomas Lewis, 1907-1982. The papers contain little concerning Lewis' work before 1914, and no clinical research notes, except for a few odd items in section F, which is largely composed of abstracts and notes on journal articles. However, there is extensive correspondence with colleagues internationally about cardiac research 1910-1944 (sections A, B), and material relating to his wartime work at the military heart hospitals at Colchester and Hampstead and with the Ministry of Pensions (section C).

The papers contain much to do with the establishment of Lewis's department as the first MRC clinical research department, in 1919, and his subsequent support for the establishment of other such departments and for the expansion of clinical research in general, through the Medical Research Club, which he founded in 1930.

Reviews of, and correspondence concerning, Lewis's publications, including Heart and Clinical Science Incorporating Heart, can be found in section E.

Reprints of many of Lewis's publications can be found in the publication collections of the Wellcome Library.

Papers of Marthe Vogt, relating almost entirely to Vogt's scientific career, 1895-1988. Personal material is found in section A and includes a rare set of publications by her distinguished scientist parents Oskar and Cécile Vogt (A/1/2-4), a bibliography of Oskar Vogt (A/1/1), plus biographical information on Marthe Vogt (A/2) and various certificates of awards presented to her (A/3). Section B chiefly comprises notebooks and other papers relating to her experimental research, from Vogt's Berlin days through to the early 1980s. This research, meticulously recorded by Vogt, formed the background to many of her important and seminal papers in the field of neurotransmitters. The bulk of the collection is formed by Section C; 20 boxes of Vogt's correspondence covering all aspects of her work and career, chiefly from her arrival in Britain in 1935 up until 1988. This has been listed in detail and is arranged alphabetically by name of correspondent. Section D is a rather miscellaneous grouping of material relating to various aspects of Vogt's work. It includes papers and lectures on her adrenal research (D/1), lists of those who were sent reprints of her published articles (D/2), some ephemera relating to the Institute of Animal Research at Babraham (D/3), Vogt's University of Berlin doctoral thesis 1929 (D/4/1) and some book reviews written by her between 1952 and 1983 (D/4/2). The photographs comprising Section E include portraits of Vogt's father, mother and sister taken in Germany (E/1), an excellent collection of portraits of Marthe Vogt (E/2) and series documenting her attendance at conferences all over the world (E/4) and her many colleagues-friends and contacts (E/3).

Papers of Sir Peter Brian Medawar, 1937-1991, relating to career, scientific research, and his writings on the philosophy of science; also biographical material collected by the late Dr Robert Reid.

Papers of the Lister Institute of Preventive Medicine (LIPM), 1886-1986, comprising minutes, 1886-1982; annual reports, 1895-1986; records relating to the origins and establishment of LIPM, 1889-1898; records of LIPMs links and amalgamations with other bodies, 1886-1898; records relating to vivisection, 1889-1899; Lord Lister's correspondence, 1893-1912; J L Pattison's correspondence, 1898-1903 and 1914; records relating to LIPMs organisation and administration, 1896-1949; production and distribution records for serum and vaccine lymph, 1894-1950; records relating to research projects, 1891-c1940s; records relating to LIPMs relations with outside bodies and individuals, 1889-1975; records relating to properties of LIPM; historical material; biographical material; miscellaneous papers; pamphlets relating to LIPM and associated bodies; pamphlets relating to other institutions; photographs; photocopies of letters from Lord Lister to Dr G Dean; and an index of correspondents.

Papers of the Research Defence Society, 1811-1992, comprising papers; administrative records; correspondence; minutes; records of membership, meetings and rules; annual reports; treasurers reports; accounts; RDS publications including Conquest magazine (which was called The Fight Against Disease until 1950); copies of Acts of Parliament, Bills and Royal Commissions, 1786-1915; correspondence and papers relating to animal rights Bills, 1927-1937 and 1965-1980; literature and publications used by the RDS; anti-vivisection literature; newspaper cuttings; tape recordings and films; and photographs and slides.

Handbills, leaflets, posters and publications concerning anti-vivisection, factory farming, bloodsports and general animal rights campaigns produced by a variety of organisations, including the Animal Liberation Front, Hunt Saboteurs Association, Manchester Meat-Free Zone Campaign, Compassion in World Farming, the National Anti-Vivisection Society, Manchester Animal Protection Group, Chicken's Lib, Vale and Valleys Hunt Saboteurs, the Vegan Action Group, League Against Cruel Sports, Earth Rights, Sea Shepherd Conservation Society, CAMPRAS (Campaign to Promote Respect for Animals in Schools), Animal Aid and the Bradford Animal Rights Group (1982 - 1996).

The papers consist of notes and notebooks of William Bayliss' experiments. There is also correspondence, press cuttings and photographs, a great part referring to the 'Brown Dog Affair' of 1903 and to other disputes between anti-vivisectionists and University College London.

Papers of Peter Daniel, 1971-1990, including correspondence concerning the Jenner Trust and Appeal, Physiological Society, William Gibson, and the Sir Hugh Cairns memorial, plus some notes on medical cases and Daniel's research grant applications.

Papers of Sir William Drummond Macdonald Paton, 1930-1993, chiefly comprising papers relating to his main research interests, namely underwater physiology, histamine, synaptic transmission, drug dependence, anaesthetic mechanisms, allergy electron microscopy and the history of science, particularly medical science. The collection also includes correspondence, research papers and laboratory notebooks, and papers relating to the committee work that occupied his energies. Papers from Paton's time as both a Rhodes Trustee and a Wellcome Trustee provide further evidence of the extent of his commitments in committee.

Papers relating to Paton's Chairmanship of the Research Defence Committee (1972-77) are particularly extensive and reveal the social and political pressures of the period, the passionate challenges of the anti-vivisection lobby, as well as Paton's personal commitment to a socially responsible use of animals in scientific experimentation. Papers relating to Man and Mouse: Animals in Medical Research (1984), in which Paton set out his fundamental position on animal experimentation, provide further material on this topic.

Another field of interest in which Paton expended considerable energy was that of drug dependence, particularly the pharmacological action of cannabis. Through work in laboratory and committees, and through the media and many speaking engagements, he campaigned strenuously to warn of what he judged to be the deleterious effects of cannabis, and forged campaign alliances with American colleagues who shared his concerns.

Throughout his career, Paton maintained strong links with the Royal Navy, acting as scientific adviser and consultant on deep diving and underwater physiology. This strand of his work was of enduring interest: Paton's work on the physiological properties of gases at high pressure led directly to the development of the deep-diving breathing mixture known as 'Tri-Mix', in which nitrogen is added to helium and oxygen. Paton took great pleasure in the Royal Navy achieving, in 1980, the world's deepest dive (see D/2/14).

Minutes of the Executive Council of the Animal Defence and Anti-vivisection Society, 26 May 1911-17 Aug 1916.

Official papers of Sir Frederick Hobday as Principal of the Royal Veterinary College (RVC), [1914-1937], including RVC committee papers including the Finance Committee, 1914-1921; General purposes committee, 1914-1921; and the London University Subcommittee; papers of the RVC General Purposes Committee on reorganising and rebuilding the College 1928-1933; report and memorandum of the advisory committee on the Royal Veterinary College on the siting of a research institute in veterinary pathology; report of development commission advisory committee into research on diseases of animals, 1922; memorandum of report of Ministry on the advisability of removing the Royal Veterinary College to Cambridge; Senate minutes including on a consideration of revision of BSC Veterinary Medicine at Senate, 20 Dec 1933; papers of the Academic Board, 1927-1932; minutes of Governor's meetings, 1914-1932; papers of the annual meeting of the RVC, 1914-1921 and papers relating to the building of the new College buildings at Camden Town, 1934.

Papers relating to events including the RVC 1937 opening ceremony; visit of Mayor of St Pancras to the RVC; Lord Mayor's Procession, 1931; Lord Mayor's Show, 1934; Sir Frederick Hobday Complimentary Dinner, 1933; the great thoroughbred contest, 1934; the Animals' Hospital Ball, 1933 and Flag day, 1933.

Papers relating to fundraising including RVC appeal letters, 1931-1933; Herbert Buckingham fund raising correspondence, 1927-1936; Our Dogs appeal, 1931; Dog World Appeal, 1931; Suffolk women's appeal; donations to rebuilding and endowment fund, General expenses fund (for special purposes and general expenses) and the South Eastern Jersey club appeal.

Papers relating to conferences, 1928-1932, including the National Veterinary Medical Association Congress, Sep 1929; RVC timetables; RVC monthly examination papers, 1927-1934; RCVS Examinations and mark books; papers relating to students including on scholarships and female students; financial papers including private account invoices; clocking on lists; papers relating to canine hysteria, 1934; applications and testimonials for posts in the RVC, 1933-1934; press cuttings including cuttings relating to the RVC; papers relating to the Ministry of Agriculture and Fisheries: Amendments to handbook of diseases of animal acts. Returns of outbreaks of scheduled diseases, 1927-1929; papers relating to anti-vivisection including Anti-vivisection Research Defence Society papers; inventory of books and instruments bequeathed to the College by Hobday; anti-vivisection correspondence and propaganda and anti-vivisection journals, 1932-1935 and issues of journals including the University of London Gazette and the Veterinary Journal, 1933.

Correspondence including a run of general correspondence arranged alphabetically, 1933-1936 and correspondence on topics including lectures, 1932-1934; the humane treatment and killing of animals, 1933; export of horses, 1929-1932; the Mansion House meetings, 1936; notices, 1917-1927; and the Royal visit to open the new buildings at the RVC, 1937. Correspondents include Margaret Rees, 1933; London livery companies; the Royal College of Veterinary Surgeons; Toye Vise; overseas colleagues; the University of London, 1934-1935; the Ministry of Agriculture and Fisheries; James Basil Buxton, 1936 and Miss Hodge (Principal's secretary), 1936.

Papers relating to societies and organisations including: the Student Union Society; Students Veterinary Medical Association; Ministry of Agriculture and fisheries; Royal Society of Medicine, 1928-1934; University of London Animal Welfare Society, 1929-1934; Royal Army Veterinary Corps, 1932-1935; Model abattoir society; Silver Fox Breeders and Furriers Association; Society for the Protection of Animals in North Africa; National Greyhound Racing Society, 1933; Council of Justice to Animals, 1933; People's League of Health 1932-1933; Metropolitan Drinking Fountain Association; College of Pestology; Pharmaceutical Society of Great Britain; agricultural societies and poultry and bird societies.