Hydrocarbure

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      Hydrocarbure

      Terme générique Composé organique

      Hydrocarbure

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        Hydrocarbure

        • Employé pour Carbure d'hydrogène

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        Hydrocarbure

        1 Description archivistique résultats pour Hydrocarbure

        Doll, Sir Richard (1912-2005)
        GB 0120 PP/DOL · 1943-1998

        Papers of Sir Richard Doll arranged as follows: Section A. Correspondence and papers from Doll's period as Regius Professor of Medicine in the University of Oxford (1969-1979). Includes the administration papers of medical departments. During Doll's professorship, most of the planning and development of the John Radcliffe Hospital complex was undertaken, and many of the papers relate to this project, including building specifications and architect's plans as well as numerous reports prepared for committees on which Doll served, including those concerned with the re-organization of Oxford hospital services.

        Section B. Papers deriving from the conduct of trials and other epidemiological research. The collection contains material from a range of clinical trials in the field of gastroenterology, conducted initially under Francis Avery Jones at Central Middlesex Hospital. The trials investigated a variety of treatments of ulcers: from an investigation of the influence of smoking, to the role of blood group distribution and family history, from the efficacy of liquorice treatment to the efficacy of intragastric milk drips in uncomplicated gastric ulcer, and from comparative trials to determine rates of healing, to investigating cortisone in ulcerative colitis. Occupational epidemiology is well-represented, including material on both vinyl chloride and asbestos. The latter incremental research into the link between asbestos exposure and lung cancer (at the Turner and Newall factory in Rochdale) includes related correspondence, draft papers and original data, beginning with Doll's landmark paper of 1955. Other research-based material includes papers relating to a Medical Research Council trial of mild hypertension (completed in 1985), for which Doll acted as Chair of the Ethical Committee. Papers on smoking and lung cancer are less well-represented: spanning the period 1956-1972, they do not, unfortunately, include papers from formative research conducted with Bradford Hill. Correspondence relating to ISIS-3: Third International Study of Infarct Survival (for which, Doll acted as Chair of the Data Monitoring Committee) can be found at D/3/82, amongst the lecture papers where it was originally filed.

        Section C. Doll's international reputation prompted a number of requests for his professional assistance, from both private and public sectors. In addition to formal consultancy conducted in America and Europe, Doll's international lecturing itinerary sometimes incorporated local consultancy - see, for example, D/3/41 (Portsmouth Naval Shipyard Study), D/3/42 (correspondence with Shell Oil, Houston, concerning peer-review of a case-control study of fourteen leukaemia deaths at an oil-refinery), or D/3/54 (a new Centre for population health studies in Tasmania). More extensive consultancy is represented by papers concerning the Spanish Toxic Oil Syndrome: the WHO invited Doll to weigh evidence gathered to determine the cause of the epidemic and prepare an expert report.

        Section D. Lecture texts and papers, published and unpublished from 1968 to 1991. Many files contain germane correspondence, notes and background material. For instance, D/1/20 ("Osler's English School") contains brief correspondence with the Dept of Pathology, Radcliffe Infirmary, Oxford on Osler's post-mortem record; D/1/32 ("Pott and the path to prevention") contains photocopied medical notes of James Chard, chimney sweep (St Batholomew's Hospital, 1848); D/2/28 ("Avoidable cancer: attribution of risk") contains clinical correspondence on beta-carotene; and D/3/24 ("Medical effects of smoking: problems and perspectives") includes correspondence with Austin Bradford Hill on the origins of the prospective study of doctors and their smoking habits. Some additional papers, prior to 1968, can be found in Section B, where they are filed together with contemporaneous research materials.

        Section E. Audio and video tapes amongst Doll's papers. A small collection of materials drawn from 1981-1984, including an interview on Japanese television.

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