The vast majority of the material relates to Dent's research and clinical interests and falls into four main categories: correspondence files; files created around the publication of papers; lecture notes and symposium papers; and case/research notes. There are also smaller quantities dealing with other aspects of his career, such as the administration of UCH Metabolic Ward. The papers thus reflect most of Dent's scientific and clinical interests. This research is mainly represented by the abstracted documentation which he kept with drafts of his published papers (see section E.1) and also by correspondence about cases and clinical case notes (see section C.5). To a lesser degree they also illustrate the work at the laboratory bench which underpinned much of this research. For example, a file of unidentified paper chromatograms has been preserved (C.2/10) to illustrate one of Dent's methods of working, as described by his colleague, Heathcote, and quoted in the Biographical Memoirs of Fellows of the Royal Society, 1978: 'Paper chromatograms were not to be thrown away. They were filed and, since the colours faded, the outline of each spot was drawn in and the intensity of the colour was indicated by a number.' The way in which Dent compiled a large series of files around drafts of scientific papers also illustrates the importance of the published paper to him as a stage in the research process. An incomplete collection of reprints of Dent's published papers may be found in section E.2 of the collection.

Papers of Dame Harriette Chick: this collection represents a relatively limited record of Chick's long and active career. It is particularly strong on the period around her important work in Vienna, 1919-1921, and includes some material relating to other research on nutritional questions.

The papers are very extensive though there are some lacunae, probably attributable to Chain's many changes of workplace. The early biographical period is sparsely documented, there are sporadic gaps in the correspondence files, and there is no original documentation of the penicillin research at Oxford (although there are many historical accounts and much correspondence about the history of penicillin). The surviving biographical material provides documentation of the arrangements for Chain to live and work in Britain, later honours and awards and his musical interests, and family correspondence, photographs and press-cuttings. There are very substantial records of his later career at the Istituto Superiore di Sanità and Imperial College, London, including his continuing contributions to biochemical problems such as carbohydrate metabolism, ergot alkaloids, edible proteins and aeration studies. The Imperial College material also contains records of the creation, administration, finance and architectural design of the Biochemistry Department, and developments in the Department after Chain's statutory retirement in 1973. Additional information about Chain's research is available in the documentation of his very extensive consultancy agreements and collaborative work with industrial firms such as Astra, Beechams and Rank Hovis McDougall, and records relating to government, grant-giving and charitable bodies such as the British Heart Foundation, Cancer Research Campaign and Medical Research Council which contributed to the funding of his research. There is much material on Chain's lectures, addresses and broadcasts, and on his extensive travel on visits and conferences, which includes a substantial number of unpublished talks.

An exceptional feature of the Chain papers is the documentation of the large number of Israel and Jewish organisations with which he was associated, especially the Weizmann Institute of Science, where he was a governor for many years and had at one time considered taking up an appointment.

The collection provides good documentation of many aspects of McIlwain's career and his contribution to the development of neurochemistry in the UK and internationally.

Section A, Biographical, brings together obituaries, curricula vitae and bibliographies, and material relating to the various stages of McIlwain's scientific career, especially in the 1930s and 1940s, his appointment to the Biochemistry Chair at the Institute of Psychiatry in 1954 and the symposium held in his honour on his retirement in 1980. The section also presents a significant body of material relating to McIlwain's undergraduate studies at King's College, University of Durham, including essays and notebooks.

Section B, Institute of Psychiatry, is principally papers relating to the activities of McIlwain's own Department of Biochemistry and especially its teaching programme in neurochemistry. There is also material relating to various government and University of London enquiries into medical education.

Section C, Research, includes copies of McIlwain's M.Sc. and Ph.D. theses, notes, drafts and reports for early work in the 1930s and correspondence 'from the Lab' for the 1930s and 1940s.

Section D, Publications, lectures and broadcast, is the largest in the collection. It presents significant documentation, especially correspondence, relating to his textbook Biochemistry and the central nervous system which went through five editions, 1955-1985, and important editorial correspondence for the Biochemical Journal (member of the Editorial Board, 1946-1950), Biochemical Pharmacology and Journal of Neurochemistry. There are also drafts for lectures and seminars for scientific audiences in the UK and abroad, principally from the 1960s onwards.

Section E, Societies and organisations, documents McIlwain's involvement with a number of UK and international bodies including the Biochemical Society, the International Brain Research Organisation and the International Society for Neurochemistry (ISN) of which he was a founder member and from 1984 'Historian' of the Society with responsibility for its archives.

Section F, Visits and conferences, covers the period 1947-1993 and is of particular interest for its documentation of the historical sessions which McIlwain organised at ISN meetings.

Section G, Correspondence, presents an alphabetical sequence of McIlwain's correspondence including significant exchanges with a number of distinguished mentors and contemporaries such as G.R. Clemo, F. Dickens, K.A.C. Elliott, P.G. Fildes, S.S. Kety, H.A. Krebs, Derek Richter and F.L. Rose, and a chronological sequence of shorter scientific correspondence covering the period 1938-1992.

There is also an index of correspondents.

Papers of Professor Thomas Richard Parsons, 1922-1959, including correspondence, lecture notes and memoranda, mainly 1920s-1930s.

Tape recordings of interviews with the Biochemistry Society, on Albert Chibnall's life and work and the development of biochemistry in Britain, with transcripts, 1983-1984.

Correspondence on the enzyme phosphotase, 1932; correspondence, notes, lists, pamphlets etc re talks to forces (general and on first aid) during Second World War; anatomical and physiological information supplied to RAF; personal correspondence, 1940-1945.

Papers of Patricia Hannah Clarke, 1963-2003, comprising biographical material including autobiographical material compiled for Clarke's personal record as a Fellow of the Royal Society; curriculum vitae; video of an interview for the Biochemical Society; papers relating to Deer Park School, Cirencester of which Clarke was a Governor, 1988-1999 and correspondence with local and national politicians on education, tobacco advertising and asylum seekers.

Papers relating to Clarke's interest in the historical contribution of women scientists and her concern in encouraging women scientists. Includes, correspondence, notes, printed reports and photocopied material used for a number of activities including her lecture 'Women in Science at University College, 1878-1978', 1992; Royal Society meeting on 'Women in Science and Technology: opportunities for change?', 28 May 1993; papers relating to Clarke's service on the Committee on Women in Science, Engineering and Technology and a meeting on Women in Science at the Royal Society, 27 Mar 2001.

Publications including an incomplete set of offprints of Clarke's works; papers relating to her biographical memoirs of Roger Yate Stanier and Michael Douglas Lilly and her entry for Muriel Robertson for the New Dictionary of National Biography; lecture material including for Clarke's Royal Society Leeuwenhoek Lecture 'Experiments in microbial evolution: new enzymes, new metabolic activities', 1979, and the 19th J D Bernal Lecture, 'New directions in biology: basic science and biotechnology', delivered at Birkbeck College London, 1988.

Papers relating to eight UK and overseas societies and organisations, 1975-2001, including the British National Bibliographical Research Fund, the Royal Society, the Palm Oil Research Institute of Malaysia and the Research Grants Council, Hong Kong.

Papers relating to Clarke's visits and conferences, 1971-1998, including visits to the Far East including Singapore, Malaysia, China and Hong Kong and meetings marking the centenary of the birth of J B S Haldane, 1992.

Correspondence, including with researchers at University College London, colleagues in the UK and scientists in the USA and Europe. Correspondents include R E Drew, B W Holloway, S Brenner; H L Kornberg, R D Sager and R Y Stanier.

Records of Imperial College relating to the University of London, 1901-1989, including correspondence concerning syllabuses and examinations, 1901-1905; Principal's correspondence, 1910-1914; centenary celebrations, 1935; 150th anniversary, 1986; student accommodation, 1943-1944; Commissioners, 1927-1928; University of London Act and Statutes, 1926-1956; reports and proposed Act, 1975-1981; establishment of Imperial College as a University School, 1907-1908; correspondence with the Court concerning grants, 1930-1946; visitations and inspections, 1923-1985, including reports; papers relating to Quinquennial estimates, visits, developments and policy, 1946-1980, including Rector's papers, 1957-1969; academic plan, 1965-1970; governance of the university, notably Rector's correspondence, 1970-1983; reports, 1972-1982; Senate minutes, 1987-1989 (UL4-ULB);

Military Education Committee and Officers' Training Corps correspondence and papers, 1908-1958, including D Company roll book, 1927-1936; University Air Squadron correspondence, 1935-1939 (ULC); Conference and Committee papers on Engineering, and award of degrees, 1909-1926; correspondence concerning the recognition of Imperial College courses, 1945-1969; entrance and pass requirements for BSc degrees, 1954-1963; papers relating to postgraduate courses, 1961-1987 (ULG); correspondence relating to examinations and curricula, 1908-1934; student registration, 1952; confidential theses, 1940-1945 (ULH); Boathouse Committee papers, 1934-1947; University of London Students' Union ephemera, 1989 (ULM);
papers relating to the Nuclear Reactor Centre, Silwood Park, 1958-1980, notably opening, 1964-1965; purchase of the reactor, 1958-1965; Reactor Safety Committee, 1964-1974 (ULN);
papers concerning University Chairs and Readerships, 1908-1968, including regulations, 1922; correspondence concerning proposed Chairs and appointments, 1943-1968; Chairs tenable at Imperial College, 1943-1957; conferment of title of Professor and Readerships, 1931-1965; endowment of a Chair and Readership in Electrical Engineering, 1953-1958; applications for Assistant Professorships in Mining and Botany, 1908-1910 (ULO); papers concerning appointments to Chairs, with some papers concerning funding and administration for the Departments of Aeronautics, 1943-1975; Biochemistry, 1955-1979; Biology, 1952-1953; Botany including Biochemistry and Plant Physiology, 1936-1979; Chemical Engineering and Chemical Technology, 1935-1977; Analytical Chemistry, 1964-1975; Organic Chemistry, 1937-1978; Physical Chemistry, 1937-1977; Civil Engineering, 1945-1973; Computing and Control, 1974-1977; Electrical Engineering, 1944-1978; Geology, 1929-1975; Industrial Sociology, 1967-1978; Mathematics, 1946-1978; Mechanical Engineering, 1931-1978; Metallurgy, 1939-1976; Meteorology, 1933-1974; Mining, 1912-1980; Physics, 1937-1977; Zoology, 1930-1977 (ULP); appointments of readers in the Departments of Aeronautics and Aerodynamics, 1949-1972; Botany, 1942-1970; Chemical Engineering and Chemical Technology, 1932-1970; Inorganic and Physical Chemistry, 1937-1965; Organic Chemistry, 1944-1971; Civil Engineering, 1946-1977; Computing and Control, 1967-1968; Electrical Engineering, 1947-1965; Geology, 1936-1976; Mathematics, 1932-1977; Mechanical Engineering, 1936-1967; Metallurgy, 1937-1970; Meteorology, 1938-1970; Mining, 1950-1975; Physics, 1938-1970; Zoology, 1937-1970 (ULR);
correspondence concerning the recognition of college staff as teachers of the University, 1908-1949; establishment of the London Graduate School of Business Studies, 1963-1966; collaboration with Queen Elizabeth College, 1968-1981; with the Royal Postgraduate Medical School, 1968-1974; correspondence with Royal Holloway College, 1918-1974; with University College concerning a course on air navigation, 1936-1953 (UM).

Collections of reprints, 1891-1945, on topics including basal metabolism, temperature, radiation, hygiene, thermal adjustment and barometric pressure. These reprints were collected by Sir Charles Martin, although very little of the reprints were written by him. Many of the files contain manuscript notes by Martin, usually on other articles. Some of the reprints have been annotated.

Papers of Sir Robert McCarrison including 149 posters illustrating nutrition observations and experiments, 1913-c.1947; memorabilia including notes for speeches and letters received, 1931-1960; correspondence with Nutrition Society and Oxford University Press, 1950s; photograph album of Coonoor including the Pasteur Institute, 1920s-1930s. Letters to McCarrison from his former assistants in Nilgiri District, Mula Singh and Krishnan, on the publication of the Festschrift, can be found in B.5. His interest in deficiency diseases was aroused by his observations of the distribution of goitre and cretinism in Gilgit, where he served from 1904, and the posters in Section A illustrate his observations and experiments on the effects of diet on metabolism. A list in B.1 includes some of the titles of the posters in section A, but also mentions others not found.

Personal papers, letters, diary notes of First World War service, photographs, etc of Sir William Maddock Bayliss, 1877-1923. Also papers on EH Starling (1866-1927), physiologist, 1892-1927, which include letters of EA Sharpey-Shafer (1850-1935), physiologist, and AV Hill (1886-1977), physiologist; and letters of F Gowland Hopkins (1861-1947), biochemist, 1924-1936.

Papers of Thaddeus Robert Rudolph Mann, 1938-1984; comprising biographical and bibliographical material, notebooks and reprints on enzyme research, 1938-1954; photographs of the Molteno Institute of Biology and Parasitology, Cambridge, 1925-1960.

Papers of Archibald Gilpin including notebooks, 1923; case notes; writings, 1930s-1940s; and papers on clinical trials of cortisone.

Papers of Sir Edward Dodds, relating in part to his professional life and in part to his historical and other outside interests. They include notes and correspondence about the illnesses of King George V and his daughter Princess Mary as well as biographical material about Dodds himself.

Papers of John M Wrigglesworth, 1963-1985, comprise records reflecting his role at Chelsea College, as Chair of the Association of University Teachers (AUT) and reflect his commitment to the College and biochemistry. The collection notably includes material regarding the threat of College closure (it eventually merged with King's College in 1985), including a copy of the petition by members of Chelsea College acting through the AUT, regarding six resolutions affecting the future structure and activities of the College, [1982]; the answer of the College to the petition of some of its members concerning the discontinuance of certain academic departments, [1982]; typewritten results of a College assembly regarding the proposed closure of the Liberal Education Department, 1982; correspondence between Laurie Sapper of the AUT and Norman M Waldron of the Chemistry Department of Chelsea College, regarding a petition concerning redundancy.

The collection also includes minutes of the Senate, October 1981-February 1982; Chelsea College of Science and Technology, 1963, a history of the College and its departments and a typewritten list of research degrees awarded in Biochemistry at Chelsea College, arranged by year of award. Also including two black and white photographs of groups of people, one inscribed 'Some aspects of modern biochemistry!!', the reverse of the photograph reads 'Swinburne, Stevens, Prenton, Howalt and David Peg', the second 'Stevenson, Martin, Jean, Spencer, Mrs Beard, Miss Young from Lyn Fitschen'.

The papers of Hugh Davson comprise correspondence, working papers and printed reports, 1950-1988; including correspondence with the Medical Research Council, notably project applications and progress reports, 1951-1978; concerning Davson's publications, with reviews, 1962-1978; with the Wellcome Trust, 1974-1980; descriptions of recent research on the eye, 1970-1978; correspondence between Davson and colleagues in the United Kingdom, Europe and North America, mainly on administrative and publishing matters, including grant applications, conference organisation and reviews of new articles and books, 1958-1980.

The collection comprises minutes and supporting paperwork for meetings of the Committee of Management of the Audio-Visual Centre; teaching and training notes including lecture notes and questionnaires; production accounts and financial papers; shooting and activity logs and production notes; video tapes of events at the University of London; a photograph album; audio-visual reels (NOT YET CATALOGUED); annual reports and printed material including workshop handbooks, catalogues, newsletters and a review of the Audio-Visual Centre.

Papers of Sir Humphrey Davy Rolleston, c 1940, comprising 10 files of manuscript material containing notes for articles on subjects such as the thymus, pineal, pancreas, carotid body, diabetes, and tuberculosis; notes for the review of a volume on the Massachusetts General Hospital, 1939; biographical notes on individuals including Caspar Bartholinus, Edmund Dickinson, and Jonathan Goddard; and a list of the biographical notes sent to the Royal College of Physicians in 1945. The notes are written on recycled correspondence and papers dating from the late 1930s to the early 1940s.

Note-books of William Dobinson Halliburton chiefly of lecture notes taken while a student at University College, London. Author's holograph MSS. Produced in London, 1874-1902.

Papers of Marthe Vogt, relating almost entirely to Vogt's scientific career, 1895-1988. Personal material is found in section A and includes a rare set of publications by her distinguished scientist parents Oskar and Cécile Vogt (A/1/2-4), a bibliography of Oskar Vogt (A/1/1), plus biographical information on Marthe Vogt (A/2) and various certificates of awards presented to her (A/3). Section B chiefly comprises notebooks and other papers relating to her experimental research, from Vogt's Berlin days through to the early 1980s. This research, meticulously recorded by Vogt, formed the background to many of her important and seminal papers in the field of neurotransmitters. The bulk of the collection is formed by Section C; 20 boxes of Vogt's correspondence covering all aspects of her work and career, chiefly from her arrival in Britain in 1935 up until 1988. This has been listed in detail and is arranged alphabetically by name of correspondent. Section D is a rather miscellaneous grouping of material relating to various aspects of Vogt's work. It includes papers and lectures on her adrenal research (D/1), lists of those who were sent reprints of her published articles (D/2), some ephemera relating to the Institute of Animal Research at Babraham (D/3), Vogt's University of Berlin doctoral thesis 1929 (D/4/1) and some book reviews written by her between 1952 and 1983 (D/4/2). The photographs comprising Section E include portraits of Vogt's father, mother and sister taken in Germany (E/1), an excellent collection of portraits of Marthe Vogt (E/2) and series documenting her attendance at conferences all over the world (E/4) and her many colleagues-friends and contacts (E/3).

Reports, diaries, memoirs, photographs and memorabilia given to the Royal Army Medical Corps Museum and Library by former officers and men of the Corps. Some date back to Marlborough's campaigns of the late 17th century; there is also material relating to the continuing European and Imperial conflicts of the 18th and early 19th centuries, the Crimean War (1854-1856), the Boer War and the Balkan conflicts of the early 20th century, the two World Wars, the Korean War and other smaller conflicts thereafter.

Papers of John Lowndes comprising typescript papers titled `Departmental Story', An account of the history of Department of Chemistry and Biochemistry, St Thomas's Hospital Medical School, John Lowdes FRIC, 1957; manuscript list of lecturers in Chemistry, Professors of Chemistry and Biochemistry.
Also contains some related letters of Thomas McLachlan, Secretary of St Thomas Hospital, concerning the accuracy of some details, 1982-1984.

Papers and correspondence of Ernest Hubert Francis Baldwin, 1930-1970.

The main deposit includes biographical papers, largely documenting Baldwin's academic career from 1934 onwards, including his appointment to the Chair of Biochemistry at University College London, 1950; correspondence, 1951-1968, including personal correspondence and exchanges with scientific colleagues; documentation on Baldwin's research, especially in notebook form, comprising notebooks, 1930-1933, including material documenting Baldwin's work at Cambridge with Dorothy Mary Moyle Needham, Joseph Needham and John Yudkin, a continuous sequence of ten notebooks documenting his research, 1934-1948, and notebooks kept at Woods Hole, 1948, and at Scripps, 1956-1957; extensive material relating to publications, lectures and broadcasts, illustrating Baldwin's role as writer and lecturer on biochemical matters; drafts and correspondence relating to his principal biochemical texts such as Dynamic Aspects of Biochemistry and The Nature of Biochemistry; documentation relating to public and invitation lectures and extensive teaching material prepared for his biochemistry courses at Cambridge and University College London, showing signs of revision and rearrangement, and evidence that they were used in the preparation of some of Baldwin's books; material on visits and conferences, 1948-1965, much of it documenting Baldwin's visits to the USA to attend conferences, give lectures at academic institutions, undertake research and take up visiting professorships; a little printed material on the First International Congress of Biochemistry at Cambridge in 1949.A supplementary deposit comprises biographical material, including documentation on the award of the 1952 Cortina Ulisse Prize by Edizioni Scientifiche Einaudi for the Italian edition of Baldwin's Dynamic Aspects of Biochemistry; photographic materials, including two photograph albums recording the visit to Italy during which he received the Cortina Ulisse award and a group photograph of the participants at the Third International Congress for Experimental Cytology, held at Cambridge in 1933; a small amount of material relating to Baldwin's classic biochemical texts, especially royalty statements; material on visits and conferences, including Baldwin's notes of his visit to the USSR for the All-Union Congress of Physiologists and Biochemists held in Kiev, 1955; additional material relating to Baldwin's visiting professorships in the USA for 1956-1957 (Scripps Institution of Oceanography) and 1965 (University of Kansas).

Certificates: Bachelor of Science and Doctor of Science, University of London (1912 and 1918); appointment as Fullerian Professor of Physiology, Royal Institution (1941); the Lasker Group Award (1947); Honorary Doctorate, Université de Paris (1948).

Papers of Professor Eric Crook, 1934-1982, comprising papers relating to biochemical engineering at University College London, (UCL) including Crook's historical account of the development of biotechnology; papers relating to research at UCL, collaborating with the Department of Chemical Engineering, including on the production of coenzyme A and enzymes on solid supports; and papers relating to the establishment of the postgraduate diploma in biochemical engineering, 1959.

Lecture material including drafts for Cook's Procter Memorial Lecture; papers relating to publications including material for Crook's own publications; bound volume of Crook's offprints, 1934-1964; papers relating to the founding of the Journal of Biochemical and Microbiological Technology and Engineering, 1957-1962; papers relating to the Medical Research Council, the Science Research Council and the University of Manchester Institute of Science and Technology, 1971-1978; papers relating to meetings and visits, 1967-1982 and two photographs of Crook.

Records of the Department of Botany of Imperial College, 1894-1976, including press cuttings and reports, 1959-1972; correspondence relating to Agricultural Research Council grants, 1935-1940; correspondence of staff, including Professor Sir John Bretland Farmer, 1907-1932, Professor Vernon Herbert Blackman, 1912-1939, Professor Percy Groom, 1909-1924; correspondence concerning the Chair of Plant Physiology, 1910-1912; Plant Physiology building, 1911-1916; Biochemistry block, 1919-1923; Chair of Comparative Pathology, 1915; examination papers, 1894-1969; correspondence and papers of Sir John Bretland Farmer, 1916-1928, including rubber research, Departmental annual reports, 1921-1927, proposed field station; students' schedules for the Animal Biology Division, papers relating to mathematics for botany and biology students, 1933-1946; registers of students, 1900-1953, staff, 1945-1953; notes and logbooks relating to courses, lectures and laboratory work, 1896-1960; minutes of the Brownian Club, 1935-1939; minutes of the Imperial Botanical Conference Executive Committee, 1923-1926, 1934; papers relating to departmental appointments, including headship and chairs, 1966-1976; Rectors' correspondence with the department, 1955-1976 (KB);
papers relating to the Plant Physiology Research Institute, 1911-1964, including correspondence with the Board of Agriculture and Fisheries, 1911-1918, Rothamsted Laboratory, 1935-1960 (KBA);
papers relating to the Division of Life Sciences, 1952-1987, including brochures and reports, 1969-1987; Department of Pure and Applied Biology research reports, annual reports, and course prospectuses, 1981-1987; Division of Life Sciences newsletter, prospectus, 1973-1978; papers of the Biology Working Party, 1966-1975; Professor Arthur Rutter, 1973-1982; Rector's papers relating to proposed division, 1979-1980; Advisory Panel on Life Sciences, 1978; Life Sciences Steering Group, 1978-1979; proposed merger of Botany and Zoology departments, 1966-1980 (KBB);
papers relating to the Department of Biochemistry, including press cuttings, 1960; research and annual reports, 1992-1999; correspondence relating to finance, 1965-1967; Rector's correspondence relating to the Rank benefaction, 1967-1978, with Professor Chain, 1969-1979, Rank chair of Biochemistry, 1973-1975 (KBC);
correspondence relating to the Centre for Biotechnology, 1980-1990 (KBT).

The collection is particularly noteworthy for its full documentation of all aspects of Pirie's research, development and promotion of leaf protein for human comsumption. It is divided into the following sections:

Section A, Biographical. It includes obituaries, a copy of the Royal Society Biographical Memoir, a little documentation of undergraduate work, and historical material assembled by Pirie relating to J Brachel, J B S Haldane, F G Hopklins, and H H Mann. Miscellaneous material includes Pirie's philosophical notes on the nature of life the scientific method and other topics.

Section B, Research notebooks. These complete the sequence of numbered notebooks listed in the 'Catalogue of the Papers of Sir Frederick Charles Bawden including the papers of Alfred Alexander, Peter Kleczkowski and Norman Wingate Pirie' and also deposited in the Archives of the Royal Society. The sequence presented here runs from 1929-1996, with the missing notebooks to be found in the Bawden collection. The work documented includes Pirie's earliest research with A A Miles on 'Brucella abortus' and 'Brucella mellitensis', his research with F C Bawden on viruses, and the many facets of his work on leaf protein to the end of his life. There are also two numbered notebooks not included in the sequence which date from the 1940s.

Section C, Leaf Protein work. This is the largest section in the collection and documents the work for which Pirie became widely known. The material comers Pirie's own research work on leaf protein, his interest in leaf protein work worldwide, the promotion of leaf protein and the development of equipment, especially suitable for use in less developed countries, which could be used to extract it. There is documentation of Pirie's struggles within the Agricultural Research Council to find support for his work, his reports on progress and later fund raising for his reasearch. There is material relating to design and construction of leaf protein apparatus of various types. Pirie believed strongly that leaf protein could make a positive contribution to nutrition in poorer countries and trials were undertaken in India, Jamaica and other countries. Latterly he found backing for his work from the 'Find Your Feet' charity and this relationship is documented. Also of interest is Pirie's interest in promoting leaf protein, including sample recipes using the foodstuff.

Section D, Other Research interests. This focuses on Pirie's earlier research, including the work for which he was elected to the Royal Society and was awarded the Copley Medal. It is not extensive and should be consulted alongside the notebooks in Section B. It is presented by topic and includes research on tobacco mosaic and tomato bushy stunt viruses by Pirie and F C Bawden in the 1930's, work on 'Brucella abortus' in the 1930's and 1940's and bracken extraction in the 1950's. There is also material relating to various alternative sources of protein, including seafood, which relates to this interest in nutrition. Miscellaneous material includes documentation of Pirie's lobbying on behalf of 'biochemical engineering' research in the 1950's.

Section E, Drafts and Publications. This presents drafts and related material including publication on food resources and his 1987 book 'Leaf Protein and its by-products in human and animal nutrition', a small number of book reviews and a little editorial correspondence. The bulk of the section, however, comprises a sequence of Pirie's volumes of bound offprints, from 1929 to 1991 (with material for 1992-1996 unbound). This sequence is more than just a full record of Pirie's published work output, as intercalated or pasted to pages of the volumes are typescripts of unpublished work or work not published in full, reports on research, visits abroad etc, correspondence, and letters to the press on a wide variety of topics including nuclear weapons, the Communist Party, space exploration, scientific writing and world nutrition. The offprints themselves may bear later manuscript annotations and typescript notes by Pirtie, giving improved methods, corrections and later bibliographical references.

Section F, Visits and Conferences. These document a few of Pirie's visits 1946-1989. There is material relating to extended visits to the USA in 1946, to Czechoslovakia, the USSR and China in 1952, and later visits in connection with leaf protein work. The lack of coverage is partially compensated for by the quality of some of the documentation of the visits, including Pirie's manuscript and typescript notes and his official reports.

Section G, Correspondence. This is again partial in its coverage. The bulk relates to Pirie's work on leaf protein. There are also individual letters from significant correspondents, from the 1930's on, including A Szent-George, J B S Haldane, G C de Hervey, Sir Peter Medawar, T Svendberg, R L M Synge etc, which Piries appears to have kept for historical reasons. The correspondence is presented in alphabetical order by correspondent.

The majority of papers in this collection concern Trowell's work on fibre, carried out in close cooperation with Denis Burkitt, exploring its role in the prevention of obesity, diabetes and coronary heart disease. There are no primary sources from the period Trowell spent as Senior Physician at the Mulago Hospital, Uganda, 1930-1958, where he was one of the key researchers into the protein-calorie malnutrition disease kwashiorkor. However, publications can be found at C.1 and the work is discussed in transcripts of taped reminiscences (A.2), and in Trowell's biography (A.5).

Section D of this list consists of papers generated by Trowell's engagement in the debate on the interface of religion and medicine.

Papers relating to Robert Thompson's research and career, 1931-1996, including personal and biographical; articles, reprints, reports, minutes, correspondence and photographs re development of British Anti-Lewisite during World War II, effects of nerve gases in warfare and civil strife, 1960s-1990s, and multiple sclerosis research; notes of lectures on biochemistry, 1952-1975; minutes, reports, etc, of International Union of Biochemistry, 1955-1980; papers re role in Royal Society and Wellcome Trust; biographical writings on R T Grant, FRS (1892-1989), Sir R A Peters, FRS (1889-1982), and G P Wright, (1898-1964).

Papers of the Wellcome Bureau of Scientific Research (WBSR), 1913-1939, comprising reports, administrative records, correspondence and publications. Including papers relating to the Wellcome Chemical Research Laboratories (WCRL), Wellcome Physiological Research Laboratories (WPRL), Wellcome Museum of Tropical Medicine and Hygiene, Wellcome Entomological Field Laboratories (WEFL), and Burrough's Wellcome and Co. Also containing papers of Andrew Balfour and papers of Charles Morley Wenyon.

Papers of the Burroughs Wellcome and Co arm of the British Insulin Manufacturers (BIM) including correspondence, marketing, production and research of insulin. Most of the papers date from 1938-1953. Also including British Insulin Manufacturers committee minutes.

Papers of John Gaddum including correspondence [1954]-1964; Cambridge Biochemistry Laboratory journals 1923-1930; reprints and photographs. These extant papers by no means reflect the whole of Gaddum's career. They date mostly from [1957]-1964, when he was Director of the Agricultural Research Council Institute of Animal Physiology at Babraham, Cambridge.

This small but important collection is concerned with the research and development of penicillin. Heatley's laboratory notebooks (A.1-3), October 1939-June 1941, and sketches and diagrams of apparatus, 1941 (C. 1-5) form the core of the collection. The famous experiment of 25 May 1941 on the 'Curative Effect of Penicillin' on mice is recorded in notebook A.2. There are also diary entries, narratives and explanatory notes, some prepared by Heatley expressly for the collection. The correspondence and reports exchanged between Heatley and Florey (section D.) is a set of photocopies, included to provide a complete account of the collaboration between the two on the penicillin project.

Copy documents collected by Sir Henry Dale c 1959 relating to the controversy over the responsibility for the discovery of insulin in Toronto in 1922.

Papers of Malcolm Lilly, 1957-2003, comprising biographical papers including obituary; curriculum vitae; bibliography; list of theses supervised and an account of Lilly's efforts to secure membership of the Institution of Chemical Engineers.

Notebooks, 1962-1998 and research notes, 1965-1997, including on control systems, fermentation and progesterone conversion.

Papers relating to biochemical engineering at University College London (UCL), including on the history of development of biochemical engineering at UCL; the Advanced Centre for Biochemical Engineering; the Interdisciplinary Research Centre; research grants, teaching, training and personnel.

Publications by Lilly, 1962-2003; manuscript and typescript drafts for publications and unpublished drafts and correspondence relating to journals with which Lilly was associated with as author, reviewer or editor.

Transcripts of Lilly's public and invitation lectures, 1966-1996, including on 'Immobilised Enzyme Reactors', Developments in Biocatalysis', 'Two-liquid phase biocatalytic reactors', 'Industrial use of Biocatalysts for Asymmetric Synthesis' and 'Biochemical Engineering - It's Contribution to Society.' Also untitled and draft lecture notes and visual material.

Papers relating to twenty four British and international organisations and societies including the European Commission, the European Federation of Biotechnology; the International Organisation for Biotechnology and Bioengineering and the Institute for Biotechnology Studies.

Papers relating to Lilly's consultancy work with twenty one commercial organisations including Beckman Instruments; Beecham Group Ltd and Merck Sharp and Dohme Research Laboratories.

Papers relating to visits and conferences, 1964-1998, including programmes, lists of participants; abstracts and Lilly's notes on proceedings.

Correspondence, 1966-1998, including references and recommendations.